Search Results - "Madziva, Michael"

Metformin Prevents Low-dose Isoproterenol-induced Cardiac Dilatation and Systolic Dysfunction in Male Sprague Dawley Rats by Peterson, Vernice R., Norton, Gavin R., Madziva, Michael T., Makaula, Siyanda

“…Myocardial metabolic abnormalities are well-recognized alterations in chronic heart failure, effects that may contribute to progressive cardiac dysfunction…”
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Curdlan-Conjugated PLGA Nanoparticles Possess Macrophage Stimulant Activity and Drug Delivery Capabilities by Tukulula, Matshawandile, Hayeshi, Rose, Fonteh, Pascaline, Meyer, Debra, Ndamase, Abongile, Madziva, Michael T., Khumalo, Vincent, Lubuschagne, Philip, Naicker, Brendon, Swai, Hulda, Dube, Admire

“…Purpose There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune…”
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Measurement of body temperature in normothermic and febrile rats: Limitations of using rectal thermometry by Dangarembizi, Rachael, Erlwanger, Kennedy H, Mitchell, Duncan, Hetem, Robyn S, Madziva, Michael T, Harden, Lois M

“…Abstract Stress-induced hyperthermia following rectal thermometry is reported in normothermic rats, but appears to be muted or even absent in febrile rats. We…”
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Glu2.53(90) of the GnRH receptor is part of the conserved G protein-coupled receptor structure and does not form a salt-bridge with Lys3.32(121) by Manilall, Ashmeetha, Stander, B. Andre, Madziva, Michael T., Millar, Robert P., Flanagan, Colleen A.

“…GnRH receptor mutations, Glu2.53(90)Lys and Glu2.53(90)Asp, cause congenital hypogonadotropic hypogonadism. The Glu2.53(90) side-chain has been proposed to…”
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Constitutively active CCR5 chemokine receptors differ in mediating HIV envelope-dependent fusion by de Voux, Alex, Chan, Mei-Chi, Folefoc, Asongna T, Madziva, Michael T, Flanagan, Colleen A

“…The CCR5 chemokine receptor is a rhodopsin-like G protein-coupled receptor that mediates the effects of pro-inflammatory β-chemokines. CCR5 is also the major…”
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Erratum to: Curdlan-conjugated PLGA Nanoparticles possess macrophage stimulant activity and drug delivery capabilities by Tukulula, Matshawandile, Hayeshi, Rose, Fonteh, Pascaline, Meyer, Debra, Ndamase, Abongile, Madziva, Michael T., Khumalo, Vincent, Labuschagne, Philip, Naicker, Brendon, Swai, Hulda, Dube, Admire

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The potential developmental programming effect of oral curcumin on the bone health and plasma total osteocalcin of male and female rats fed a high-fructose diet during suckling and post weaning by Ibrahim, Kasimu G, Wright, Hayley L, Chivandi, Eliton, Madziva, Michael T, Erlwanger, Kennedy H

“…We investigated the effect of oral curcumin, on bone health of rats fed a high-fructose diet. Suckling pups (males = 65, females = 63) were gavage with 0.5%…”
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The carboxy-terminal tail or the intracellular loop 3 is required for β-arrestin-dependent internalization of a mammalian type II GnRH receptor by Madziva, Michael T., Mkhize, Nonhlanhla N., Flanagan, Colleen A., Katz, Arieh A.

“…•GnRH-R2 activation of ERK is dependent on β-arrestin 1.•Carboxy-terminally truncated GnRH-R2 retains β-arrestin dependent internalization.•C-terminus of…”
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The effects of high-fat diets composed of different animal and vegetable fat sources on the health status and tissue lipid profiles of male Japanese quail ( Coturnix coturnix japonica ) by Donaldson, Janine, Madziva, Michael Taurai, Erlwanger, Kennedy Honey

“…The current study aimed to investigate the impact of high-fat diets composed of different animal and vegetable fat sources on serum metabolic health markers in…”
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A Role for ADP-ribosylation Factor 6 in the Processing of G-protein-coupled Receptors by Madziva, Michael T., Birnbaumer, Mariel

“…After agonist-induced internalization, the vasopressin V2 receptor (V2R) does not recycle to the plasma membrane. The ADP-ribosylation factor (ARF) proteins…”
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Filamin a binds to CCR2B and regulates its internalization by Minsaas, Laura, Planagumà, Jesús, Madziva, Michael, Krakstad, Beate F, Masià-Balagué, Míriam, Katz, Arieh A, Aragay, Anna M

“…The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major…”
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Pyrogenic and neuroinflammatory properties of zymosan and its potential as an alternative to live yeast in antipyretic drug testing by Dangarembizi, Rachael, Rummel, Christoph D., Roth, Joachim, Erlwanger, Kennedy H., Madziva, Michael T., Harden, Lois M.

“…Zymosan, an immunogenic cell wall extract of Saccharomyces cerevisiae has potential for use as an experimental pyrogen. However, the short-lived sickness…”
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A role for K268 in V2R folding by Gouill, Christian Le, Darden, Thomas, Madziva, Michael T., Birnbaumer, Mariel

“…The V2 vasopressin receptor, a member of the rhodopsin subfamily of GPCRs, mediates arginine vasopressin control of water reabsorption in the kidney by…”
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Trafficking of green fluorescent protein-tagged muscarinic M4 receptors in NG108-15 cells by Madziva, M T, Edwardson, J M

“…The muscarinic M4 receptor for acetylcholine was tagged at its C terminus with green fluorescent protein (GFP) and expressed in NG108-15 cells, which normally…”
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The effects of high-fat diets composed of different animal and vegetable fat sources on the health status and tissue lipid profiles of male Japanese quail (Coturnix coturnix japonica) by Donaldson, Janine, Madziva, Michael Taurai, Erlwanger, Kennedy Honey

“…Objective: The current study aimed to investigate the impact of high-fat diets composed of different animal and vegetable fat sources on serum metabolic health…”
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Desensitization and Internalization of Human and XenopusGonadotropin-Releasing Hormone Receptors Expressed in αT4 Pituitary Cells Using Recombinant AdenovirusThe work was supported in part by the Wellcome Trust (054949), the Medical Research Council (G78/6046), the South African Research Council, and National Research Foundation by Hislop, James N, Madziva, Michael T, Everest, Helen M, Harding, Tom, Uney, James B, Willars, Gary B, Millar, Robert P, Troskie, Brigitte E, Davidson, James S, McArdle, Craig A

“…Nonmammalian vertebrates express at least two forms of GnRH and distinct forms of GnRH receptor (GnRH-R) have coevolved with their ligands. Mammalian and…”
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Metabolic Health of Guinea Fowl and Muscovy Ducks Fed a High-Fat Diet by Donaldson, Janine, Madziva, Michael Taurai, Erlwanger, Kennedy Honey

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Glu 2.53(90) of the GnRH receptor is part of the conserved G protein-coupled receptor structure and does not form a salt-bridge with Lys 3.32(121) by Manilall, Ashmeetha, Stander, B Andre, Madziva, Michael T, Millar, Robert P, Flanagan, Colleen A

“…GnRH receptor mutations, Glu Lys and Glu Asp, cause congenital hypogonadotropic hypogonadism. The Glu side-chain has been proposed to form an intramolecular…”
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Suppression of Caco-2 and HEK-293 cell proliferation by Kigelia africana, Mimusops zeyheri and Ximenia caffra seed oils by Chivandi, Eliton, Cave, Eleanor, Davidson, Bruce Clement, Erlwanger, Kennedy Honey, Moyo, Davison, Madziva, Michael Taurai

“…Animal-derived oils and purified fatty acids, but not indigenous fruit-tree-derived seed oils, have been used to study cell growth and differentiation. In this…”
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Desensitization and Internalization of Human and Xenopus Gonadotropin-Releasing Hormone Receptors Expressed in alpha T4 Pituitary Cells Using Recombinant Adenovirus by Hislop, J N, Madziva, M T, Everest, H M, Harding, T, Uney, J B, Willars, G B, Millar, R P, Troskie, B E, Davidson, J S, McArdle, CA

“…Nonmammalian vertebrates express at least two forms of GnRH and distinct forms of GnRH receptor (GnRH-R) have coevolved with their ligands. Mammalian and…”
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