Search Results - "Madyastha, K.M"

C-Phycocyanin: A Potent Peroxyl Radical Scavenger in Vivo and in Vitro by Bhat, Vadiraja B., Madyastha, K.M.

“…C-Phycocyanin (from Spirulina platensis) effectively inhibited CCl4-induced lipid peroxidation in rat liver in vivo. Both native and reduced phycocyanin…”
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Scavenging of Peroxynitrite by Phycocyanin and Phycocyanobilin from Spirulina platensis: Protection against Oxidative Damage to DNA by Bhat, Vadiraja B., Madyastha, K.M.

“…Peroxynitrite (ONOO−) is known to inactivate important cellular targets and also mediate oxidative damage in DNA. The present study has demonstrated that…”
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Selective Inhibition of Cyclooxygenase-2 by C-Phycocyanin, a Biliprotein from Spirulina platensis by Reddy, C.Madhava, Bhat, Vadiraja B., Kiranmai, G., Reddy, M.Narsa, Reddanna, P., Madyastha, K.M.

“…We report data from two related assay systems (isolated enzyme assays and whole blood assays) that C-phycocyanin a biliprotein from Spirulina platensis is a…”
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Crystal Structure of a Light-Harvesting Protein C-Phycocyanin from Spirulina platensis by Padyana, Anil K., Bhat, Vadiraja B., Madyastha, K.M., Rajashankar, K.R., Ramakumar, S.

“…The crystal structure of C-phycocyanin, a light-harvesting phycobiliprotein from cyanobacteria (blue-green algae) Spirulina platensis has been solved by…”
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A Novel Pathway for the Metabolism of Caffeine by a Mixed Culture Consortium by Madyastha, K.M., Sridhar, G.R.

“…A new oxidative pathway for the degradation of caffeine(1,3,7-Trimethylxanthine, I) by a mixed culture consisting of strains belonging to the…”
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C-Phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophages by Reddy, Madhava C, Subhashini, J, Mahipal, S.V.K, Bhat, Vadiraja B, Srinivas Reddy, P, Kiranmai, G, Madyastha, K.M, Reddanna, P

“…C-Phycocyanin (C-PC) is one of the major biliproteins of Spirulina platensis, a blue green algae, with antioxidant and radical scavenging properties. It is…”
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Pulegone mediated hepatotoxicity: evidence for covalent binding of R(+)-[14C]pulegone to microsomal proteins in vitro by Madyastha, K M, Moorthy, B

“…Incubation of R(+)-[14C]pulegone with rat liver microsomes in the presence of NADPH resulted in covalent binding of radioactive material to macromolecules…”
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Purification and partial characterization of microsomal NADH-cytochrome b5 reductase from higher plant Catharanthus roseus by Madyastha, K M, Chary, N K, Holla, R, Karegowdar, T B

“…A simple three step procedure was used to purify microsomal NADH-cytochrome b5 (ferricyanide) reductase to homogeneity from the higher plant C. roseus. The…”
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Antioxidant and Radical Scavenging Properties of 8-Oxo Derivatives of Xanthine Drugs Pentoxifylline and Lisofylline by Bhat, Vadiraja B., Madyastha, K.M.

“…The antioxidant and radical scavenging properties of 8-oxo derivatives of pentoxifylline, lisofylline, enprofylline (3-propyl xanthine), and 1,7-dimethyl…”
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Detergent-solubilized NADPH-cytochrome c (P-450) reductase from the higher plant, Catharanthus roseus. Purification and characterization by Madyastha, K M, Coscia, C J

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Scavenging of Peroxynitrite by Phycocyanin and Phycocyanobilin from Spirulina platensis: Protection against Oxidative Damage to DNA: Volume 285, Number 2 (2001), pages 262–266 by Bhat, Vadiraja B., Madyastha, K.M.

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Biosynthesis of β-Substituted Furan Skeleton in the Lower Furanoterpenoids: A Model Study by Gaikwad, Nilesh W., Madyastha, K.M.

“…Furanoterpenes are widely distributed in the plant kingdom. In this study we have carried out enzymatic synthesis of simple furan compounds from the molecules…”
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Transformation of a monoterpene ketone, piperitenone, and related terpenoids using Mucor piriformis by Thulasiram, Hirekodathakallu V, Madyastha, K Madhava

“…Biotransformation of piperitenone (I), 5,5-dimethyl-2-(1-methylethylidene)-cyclohexanone (II), and 2-(1-ethyl-1-propylidene)-5-methylcyclohexanone (III) was…”
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Stereoselective hydroxylation of 4-methyl-2-cyclohexenone in rats: its relevance to R-(+)-pulegone-mediated hepatotoxicity by Madyastha, K.M, Paul Raj, C

“…R-(+)-Pulegone, a monoterpene ketone, is a potent hepatotoxin. One of the major metabolites of pulegone has been shown to be p-cresol, a glutathione depletor…”
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Hepatoprotective Effect of C-Phycocyanin: Protection for Carbon Tetrachloride andR-(+)-Pulegone-Mediated Hepatotoxicty in Rats by Vadiraja, Bhat.B., Gaikwad, Nilesh.W., Madyastha, K.M.

“…Effect of C-phycocyanin (fromSpirulina platensis) pretreatment on carbontetrachloride andR-(+)-pulegone-induced hepatotoxicity in rats was studied…”
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Regulation of secondary metabolism in higher plants. Effect of alkaloids on a cytochrome P-450 dependent monooxygenase by McFarlane, J, Madyastha, K M, Coscia, C J

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Scavenging of Peroxynitrite by Phycocyanin and Phycocyanobilin from Spirulina platensis: Protection against Oxidative Damage to DNA by Bhat, Vadiraja B., Madyastha, K.M.

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Purification and Partial Characterization of Caffeine Oxidase—A Novel Enzyme from a Mixed Culture Consortium by Madyastha, K.M., Sridhar, G.R., Vadiraja, Bhat.B., Madhavi, Y.Sudha

“…Cell-free extract prepared from a mixed culture consisting of strains belonging to the genera Klebsiella and Rhodococcus grown in the presence of caffeine…”
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Biocatalyst-mediated expansion of ring D in azadirachtin, a potent insect antifeedant from Azadirachta indica by Madyastha, K.M, Venkatakrishnan, K

“…A microorganism identified as Nocardia Sp.capable of converting azadirachtin 1 into three metabolites, viz. 3-deacetylazadirachtin 2,…”
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Efficient scavenging of hydroxyl radicals and inhibition of lipid peroxidation by novel analogues of 1,3,7-trimethyluric acid by Bhat, Vadiraja B., Sridhar, G.R., Madyastha, K.M.

“…New water-soluble analogues of 1,3,7-trimethyluric acid with N-1 methyl replaced by various groups were prepared and evaluated for their ability to scavenge…”
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