Search Results - "Maduro, Morris F"

Evolutionary Dynamics of the SKN-1 → MED → END-1,3 Regulatory Gene Cascade in Caenorhabditis Endoderm Specification by Maduro, Morris F

“…Gene regulatory networks and their evolution are important in the study of animal development. In the nematode, , the endoderm (gut) is generated from a single…”
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Evolutionary Change in Gut Specification in Caenorhabditis Centers on the GATA Factor ELT-3 in an Example of Developmental System Drift by Broitman-Maduro, Gina, Maduro, Morris F

“…Cells in a developing animal embryo become specified by the activation of cell-type-specific gene regulatory networks. The network that specifies the gut in…”
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Evolution of Developmental GATA Factors in Nematodes by Eurmsirilerd, Ethan, Maduro, Morris F.

“…GATA transcription factors are found in animals, plants, and fungi. In animals, they have important developmental roles in controlling specification of cell…”
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Structure and evolution of the C. elegans embryonic endomesoderm network by Maduro, Morris F.

“…The specification of the Caenorhabditis elegans endomesoderm has been the subject of study for more than 15 years. Specification of the 4-cell stage…”
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The C. elegans intestine: organogenesis, digestion, and physiology by Dimov, Ivan, Maduro, Morris F.

“…The comparatively simple Caenorhabditis elegans intestine fulfills many of the complex functions of the mammalian digestive tract, liver, and fat tissues,…”
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Gut development in C. elegans by Maduro, Morris F.

“…[Display omitted] •The C. elegans gut is a simple 20-cell tube that carries out major digestive functions.•The gut arises from single cell through a…”
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Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm by Maduro, Morris F., Rothman, Joel H.

“…The nematode Caenorhabditis elegans is a triploblastic ecdysozoan, which, although it contains too few cells during embryogenesis to create discernible germ…”
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The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development by Broitman-Maduro, Gina, Owraghi, Melissa, Hung, Wendy W K, Kuntz, Steven, Sternberg, Paul W, Maduro, Morris F

“…The C. elegans MS blastomere, born at the 7-cell stage of embryogenesis, generates primarily mesodermal cell types, including pharynx cells, body muscles and…”
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Maternal deployment of the embryonic SKN-1 → MED-1,2 cell specification pathway in C. elegans by Maduro, Morris F., Broitman-Maduro, Gina, Mengarelli, Isabella, Rothman, Joel H.

“…We have previously shown that the MED-1,2 divergent GATA factors act apparently zygotically to specify the fates of the MS (mesoderm) and E (endoderm) sister…”
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Genetic interaction between DNA replication and the Notch signaling pathway by Maduro, Morris F.

“…The Notch pathway is a widely conserved cell signaling system found in most metazoans. In Caenorhabditis elegans, GLP‐1/Notch signaling is required for…”
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The GATA factor ELT-3 specifies endoderm in Caenorhabditis angaria in an ancestral gene network by Broitman-Maduro, Gina, Sun, Simo, Kikuchi, Taisei, Maduro, Morris F

“…Endoderm specification in Caenorhabditis elegans occurs through a network in which maternally provided SKN-1/Nrf, with additional input from POP-1/TCF,…”
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Developmental robustness in the Caenorhabditis elegans embryo by Maduro, Morris F.

“…SUMMARY Developmental robustness is the ability of an embryo to develop normally despite many sources of variation, from differences in the environment to…”
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Dynamics of a Developmental Switch: Recursive Intracellular and Intranuclear Redistribution of Caenorhabditis elegans POP-1 Parallels Wnt-Inhibited Transcriptional Repression by Maduro, Morris F., Lin, Rueyling, Rothman, Joel H.

“…POP-1, a Tcf/Lef factor, functions throughout Caenorhabditis elegans development as a Wnt-dependent reiterative switch to generate nonequivalent sister cells…”
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Specification of the C. elegans MS blastomere by the T-box factor TBX-35 by Broitman-Maduro, Gina, Lin, Katy Tan-Hui, Hung, Wendy W. K., Maduro, Morris F.

“…In C. elegans , many mesodermal cell types are made by descendants of the progenitor MS, born at the seven-cell stage of embryonic development. Descendants of…”
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Partially compromised specification causes stochastic effects on gut development in C. elegans by Choi, Hailey, Broitman-Maduro, Gina, Maduro, Morris F.

“…The C. elegans gut descends from the E progenitor cell through a series of stereotyped cell divisions and morphogenetic events. Effects of perturbations of…”
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The long isoform of the C. elegans ELT-3 GATA factor can specify endoderm when overexpressed by Broitman-Maduro, Gina, Maduro, Morris F

“…The gene encodes a GATA transcription factor that is expressed in the hypodermis and has roles in hypodermal specification and regulation of collagen and…”
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Feedforward regulatory logic controls the specification-to-differentiation transition and terminal cell fate during Caenorhabditis elegans endoderm development by Ewe, Chee Kiang, Sommermann, Erica M., Kenchel, Josh, Flowers, Sagen E., Maduro, Morris F., Joshi, Pradeep M., Rothman, Joel H.

“…The architecture of gene regulatory networks determines the specificity and fidelity of developmental outcomes. We report that the core regulatory circuitry…”
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Cell fate specification in the C. elegans embryo by Maduro, Morris F.

“…Cell specification requires that particular subsets of cells adopt unique expression patterns that ultimately define the fates of their descendants. In C…”
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MED GATA factors promote robust development of the C. elegans endoderm by Maduro, Morris F., Broitman-Maduro, Gina, Choi, Hailey, Carranza, Francisco, Wu, Allison Chia-Yi, Rifkin, Scott A.

“…The MED-1,2 GATA factors contribute to specification of E, the progenitor of the Caenorhabditis elegans endoderm, through the genes end-1 and end-3, and in…”
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Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network by Owraghi, Melissa, Broitman-Maduro, Gina, Luu, Thomas, Roberson, Heather, Maduro, Morris F.

“…In C. elegans the 4-cell stage blastomere EMS is an endomesodermal precursor. Its anterior daughter, MS, makes primarily mesodermal cells, while its posterior…”
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