Search Results - "Madsen, Martin R."

A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity by Hagemann, Christoffer A, Legart, Christian, Møllerhøj, Mathias B, Madsen, Martin R, Hansen, Henrik H, Kønig, Merete J, Helgstrand, Frederik, Hjørne, Flemming P, Toxværd, Anders, Langhoff, Jill L, Kielgast, Urd L, Gluud, Lise L, Ægidius, Helene, Rigbolt, Kristoffer T. G, Vilsbøll, Tina, Jelsing, Jacob, Knop, Filip K

“…Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present…”
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Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment by Hagemann, Christoffer A, Zhang, Chen, Hansen, Henrik H, Jorsal, Tina, Rigbolt, Kristoffer T G, Madsen, Martin R, Bergmann, Natasha C, Heimbürger, Sebastian M N, Falkenhahn, Mechthilde, Theis, Stefan, Breitschopf, Kristin, Holm, Stephanie, Hedegaard, Morten A, Christensen, Mikkel B, Vilsbøll, Tina, Holst, Birgitte, Vrang, Niels, Jelsing, Jacob, Knop, Filip K

“…Abstract Context The mechanisms underlying Roux-en-Y gastric bypass (RYGB) surgery-induced weight loss and the immediate postoperative beneficial metabolic…”
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Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis by Rauch, Alexander, Haakonsson, Anders K., Madsen, Jesper G. S., Larsen, Mette, Forss, Isabel, Madsen, Martin R., Van Hauwaert, Elvira L., Wiwie, Christian, Jespersen, Naja Z., Tencerova, Michaela, Nielsen, Ronni, Larsen, Bjørk D., Röttger, Richard, Baumbach, Jan, Scheele, Camilla, Kassem, Moustapha, Mandrup, Susanne

“…Mesenchymal (stromal) stem cells (MSCs) constitute populations of mesodermal multipotent cells involved in tissue regeneration and homeostasis in many…”
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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans by Caballero-Camino, Francisco J, Rodrigues, Pedro M, Wångsell, Fredrik, Agirre-Lizaso, Aloña, Olaizola, Paula, Izquierdo-Sanchez, Laura, Perugorria, Maria J, Bujanda, Luis, Angelin, Bo, Straniero, Sara, Wallebäck, Anna, Starke, Ingemar, Gillberg, Per-Göran, Strängberg, Ellen, Bonn, Britta, Mattsson, Jan P, Madsen, Martin R, Hansen, Henrik H, Lindström, Erik, Åkerblad, Peter, Banales, Jesus M

“…Cholestasis is characterized by intrahepatic accumulation of bile constituents, including bile acids (BAs), which promote liver damage. The apical…”
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A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity by Christoffer A. Hagemann, Christian Legart, Mathias B. Møllerhøj, Martin R. Madsen, Henrik H. Hansen, Merete J. Kønig, Frederik Helgstrand, Flemming P. Hjørne, Anders Toxværd, Jill L. Langhoff, Urd L. Kielgast, Lise L. Gluud, Helene Ægidius, Kristoffer T. G. Rigbolt, Tina Vilsbøll, Jacob Jelsing, Filip K. Knop

“…Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present…”
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483-P: Key Biochemical and Histopathological Markers of Diabetic Nephropathy Correlate with Hypertension in the Renin-AAV Uninephrectomized db/db Mouse Model by ØSTERGAARD, METTE V., SØRENSEN, IDA R., PEDERSEN, ANNEMARIE A., SECHER, THOMAS, SEMBACH, FREDERIKKE E., MADSEN, MARTIN R., FOSGERAU, KELD, FINK, LISBETH N., VRANG, NIELS

“…Introduction: Diabetic nephropathy (DN) is a long-term complication that occurs in ∼40% of diabetes patients and is a leading cause of end-stage renal disease…”
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Author Correction: Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis by Rauch, Alexander, Haakonsson, Anders K., Madsen, Jesper G. S., Larsen, Mette, Forss, Isabel, Madsen, Martin R., Van Hauwaert, Elvira L., Wiwie, Christian, Jespersen, Naja Z., Tencerova, Michaela, Nielsen, Ronni, Larsen, Bjørk D., Röttger, Richard, Baumbach, Jan, Scheele, Camilla, Kassem, Moustapha, Mandrup, Susanne

“…In the version of this article initially published, in the graph keys in Fig. 1i, the colors indicating ‘Ob’ and ‘Ad’ were red and blue, respectively, but…”
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Glucocorticoid receptor promotes osteoblast and adipocyte differentiation by recruiting and being recruited to lineage selective enhancers by Madsen, Martin R., Kassem, Moustapha, Mandrup, Susanne, Rauch, Alexander

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1598-P: Transcriptional Profiling of the Intestinal Tract in Type 2 Diabetes-Unraveling Pathophysiological Pathways for Therapeutic Insights by Gilliam-Vigh, Hannah, Ellegaard, Anne-Marie, Madsen, Martin R, Jensen, Benjamin Ah, Rigbolt, Kristoffer, Knop, Filip K

“…Introduction and Objective: Investigating the intestinal gene expression in type 2 Diabetes (T2D) may reveal novel insights into its pathophysiology. We…”
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733 HEPATOPROTECTIVE EFFECTS OF SEMAGLUTIDE IN THE GAN DIET-INDUCED OBESE AND BIOPSY-CONFIRMED MOUSE MODEL OF NASH WITH ADVANCED FIBROSIS AND HEPATOCELLULAR CARCINOMA by Heimbürger, Sebastian M⊘ller Nguyen, Nielsen, Malte H., M⊘llerh⊘j, Mathias Bonde, Oró, Denise, Madsen, Martin R., Vyberg, Mogens, Hansen, Henrik H., Feigh, Michael

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Nephroprotective Effects of Semaglutide in a Mouse Model of Hypertension-Accelerated Diabetic Kidney Disease: SA-PO222 by Bak, Stine T., Dalbøge, Louise, Christensen, Michael, Secher, Thomas, Endlich, Nicole, Drenic, Vedran, Madsen, Martin R., Hansen, Henrik H., Rune, Ida, Fink, Lisbeth N., Østergaard, Mette V.

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Comparative Transcriptomics of Human and Mouse Diabetic Kidney Disease: TH-PO223 by Sembach, Frederikke E., Østergaard, Mette V., Nielsen, Jens Christian, Christensen-Dalsgaard, Mikkel, Madsen, Martin R., Feldt-Rasmussen, Bo, Porrini, Esteban, Hornum, Mads, Fink, Lisbeth N.

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Improvement of NASH and liver fibrosis through modulation of the gut-liver axis by a novel intestinal FXR agonist by Moon, An-Na, Briand, François, Breyner, Natalia, Song, Dong-Keun, Madsen, Martin Rønn, Kim, Hongbin, Choi, Keonwoo, Lee, Yoonsuk, Namkung, Wan

“…Farnesoid X receptor (FXR) plays a pivotal role in the regulation of bile acid homeostasis and is involved in the pathogenesis of nonalcoholic steatohepatitis…”
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