Search Results - "Madsen, Mark A."

Cell Surface Proteomics Identifies Molecules Functionally Linked to Tumor Cell Intravasation by Conn, Erin M., Madsen, Mark A., Cravatt, Benjamin F., Ruf, Wolfram, Deryugina, Elena I., Quigley, James P.

“…In order to better understand the molecular and cellular determinants of tumor cell intravasation, our laboratory has generated a pair of congenic human…”
Get full text

Activity-based Protein Profiling Implicates Urokinase Activation as a Key Step in Human Fibrosarcoma Intravasation by Madsen, Mark A., Deryugina, Elena I., Niessen, Sherry, Cravatt, Benjamin F., Quigley, James P.

“…Entry of malignant cells into the vasculature (i.e. intravasation) requires proteolytic remodeling of the extracellular matrix so that tumor cells may pass…”
Get full text

Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells by Zijlstra, Andries, Seandel, Marco, Kupriyanova, Tatyana A., Partridge, Juneth J., Madsen, Mark A., Hahn-Dantona, Elizabeth A., Quigley, James P., Deryugina, Elena I.

“…A quantitative in vivo angiogenesis model employing collagen onplants placed on the chick embryo chorioallantoic membrane (CAM) has been used in this study to…”
Get full text

Functional Analysis of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Differentially Expressed by Variants of Human HT-1080 Fibrosarcoma Exhibiting High and Low Levels of Intravasation and Metastasis by Partridge, Juneth J., Madsen, Mark A., Ardi, Veronica C., Papagiannakopoulos, Thales, Kupriyanova, Tatyana A., Quigley, James P., Deryugina, Elena I.

“…The role of tumor-derived matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) in cancer cell dissemination was analyzed by…”
Get full text

Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination by DERYUGINA, Elena I, ZIJISTRA, Andries, PARTRIDGE, Juneth J, KUPRIYANOVA, Tatyana A, MADSEN, Mark A, PAPAGIANNAKOPOULOS, Thales, QUIGLEY, James P

“…The human tumor/chick embryo model involving grafting of human HT-1080 fibrosarcoma cells on the chorioallantoic membrane was used in conjunction with…”
Get full text

Altered oxidative stress response of the long-lived Snell dwarf mouse by Madsen, Mark A, Hsieh, Ching-Chyuan, Boylston, William H, Flurkey, Kevin, Harrison, David, Papaconstantinou, John

“…Several single gene mutations in mice that increase the murine life span have been identified, including the Pit-1 mutation which results in the Snell dwarf (…”
Get full text

A Proteomics Analysis of the Effects of Chronic Hemiparetic Stroke on Troponin T Expression in Human Vastus Lateralis by Rabek, Jeffrey P., Hafer-Macko, Charlene E., Amaning, James K., DeFord, James H., Dimayuga, Vincent L., Madsen, Mark A., Macko, Richard F., Papaconstantinou, John

“…Stroke disability is attributed to upper motor neuron deficits resulting from ischemic brain injury. We have developed proteome maps of the Vastus lateralis to…”
Get full text

Cell Surface Proteomics Identifies Molecules Functionally Linked to Tumor Cell IntravasationS by Conn, Erin M., Madsen, Mark A., Cravatt, Benjamin F., Ruf, Wolfram, Deryugina, Elena I., Quigley, James P.

“…In order to better understand the molecular and cellular determinants of tumor cell intravasation, our laboratory has generated a pair of congenic human…”
Get full text

Altered oxidative stress response of the long lived Snell dwarf mouse-response to 3-NPA by Madsen, Mark A

“…Several single gene mutations in mice that increase the murine lifespan have been identified, including the Pit-1 mutation (Pit1dw/dw ) which results in the…”
Get full text