Search Results - "Madsen, Lone Bruhn"

Development of an Experimental Ex Vivo Wound Model to Evaluate Antimicrobial Efficacy of Topical Formulations by Andersson, Madelene Å, Madsen, Lone Bruhn, Schmidtchen, Artur, Puthia, Manoj

“…Wound infections are considered a major cause for wound-associated morbidity. There is a high demand for alternative, robust, and affordable methods that can…”
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Insights into the Evolution of Longevity from the Bowhead Whale Genome by Keane, Michael, Semeiks, Jeremy, Webb, Andrew E., Li, Yang I., Quesada, Víctor, Craig, Thomas, Madsen, Lone Bruhn, van Dam, Sipko, Brawand, David, Marques, Patrícia I., Michalak, Pawel, Kang, Lin, Bhak, Jong, Yim, Hyung-Soon, Grishin, Nick V., Nielsen, Nynne Hjort, Heide-Jørgensen, Mads Peter, Oziolor, Elias M., Matson, Cole W., Church, George M., Stuart, Gary W., Patton, John C., George, J. Craig, Suydam, Robert, Larsen, Knud, López-Otín, Carlos, O’Connell, Mary J., Bickham, John W., Thomsen, Bo, de Magalhães, João Pedro

“…The bowhead whale (Balaena mysticetus) is estimated to live over 200 years and is possibly the longest-living mammal. These animals should possess protective…”
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Comparison of efficacy between subcutaneous and intravenous application of moss-aGal in the mouse model of Fabry disease by Dabrowska-Schlepp, Paulina, Busch, Andreas, Shen, Jin-Song, Cheong, Rachel Y, Madsen, Lone Bruhn, Mascher, Daniel, Schiffmann, Raphael, Schaaf, Andreas

“…Fabry disease (FD, OMIM 301500) is a rare X-linked inherited lysosomal storage disorder associated with reduced activities of α-galactosidase A (aGal, EC…”
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Molecular cloning and characterization of porcine Na⁺/K⁺-ATPase isoforms α1, α2, α3 and the ATP1A3 promoter by Henriksen, Carina, Kjaer-Sorensen, Kasper, Einholm, Anja Pernille, Madsen, Lone Bruhn, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Vilsen, Bente, Larsen, Knud

“…Na⁺/K⁺-ATPase maintains electrochemical gradients of Na⁺ and K⁺ essential for a variety of cellular functions including neuronal activity. The α-subunit of the…”
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Probing Skin Barrier Recovery on Molecular Level Following Acute Wounds: An In Vivo/Ex Vivo Study on Pigs by Mojumdar, Enamul Haque, Madsen, Lone Bruhn, Hansson, Henri, Taavoniku, Ida, Kristensen, Klaus, Persson, Christina, Morén, Anna Karin, Mokso, Rajmund, Schmidtchen, Artur, Ruzgas, Tautgirdas, Engblom, Johan

“…Proper skin barrier function is paramount for our survival, and, suffering injury, there is an acute need to restore the lost barrier and prevent development…”
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Porcine synapsin 1: SYN1 gene analysis and functional characterization of the promoter by Hedegaard, Claus, Kjaer-Sorensen, Kasper, Madsen, Lone Bruhn, Henriksen, Carina, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Larsen, Knud

“…Synapsin 1 (SYN1) is a phosphoprotein involved in nerve signal transmission. The porcine SYN1 promoter orthologue was cloned and characterized to provide a…”
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Identification of the porcine homologous of human disease causing trinucleotide repeat sequences by MADSEN, Lone Bruhn, THOMSEN, Bo, SØLVSTEN, Christina Ane Elisabeth, BENDIXEN, Christian, FREDHOLM, Merete, JØRGENSEN, Arne Lund, NIELSEN, Anders Lade

“…Expansion in the repeat number of intragenic trinucleotide repeats (TNRs) is associated with a variety of inherited human neurodegenerative diseases. To study…”
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Stress-free blood sampling in minipigs: A novel method for assessing 24-h cortisol profiles and drug effects on diurnal and ultradian rhythms by Rode, Frederik, Bundgaard, Christoffer, Areberg, Johan, Madsen, Lone Bruhn, Taavoniku, Ida, Hansen, Lene, Weisser, Johan, Olsen, Line Rørbæk, Elgaard, Heidi Toft, Eneberg, Elin, Didriksen, Michael

“…We developed a novel, stress-free blood sampling method for minipigs, allowing continuous cortisol monitoring over 24 h. Baseline cortisol levels exhibited…”
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Porcine dorfin: molecular cloning of the RNF19 gene, sequence comparison, mapping and expression analysis by Larsen, Knud, Madsen, Lone Bruhn, Bendixen, Christian

“…Dorfin, encoded by the RNF19 gene, is a protein containing two RING finger motifs. Dorfin functions as an E3 ubiquitin ligase that interacts with UBE2L3/UBCH7…”
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Sequence conservation between porcine and human LRRK2 by Larsen, Knud, Madsen, Lone Bruhn

“…Leucine-rich repeat kinase 2 (LRRK2) is a member of the ROCO protein superfamily (Ras of complex proteins (Roc) with a C-terminal Roc domain). Mutations in the…”
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Porcine oocyte mtDNA copy number is high or low depending on the donor by Pedersen, Hanne Skovsgaard, Løvendahl, Peter, Larsen, Knud, Madsen, Lone Bruhn, Callesen, Henrik

“…Oocyte capacity is relevant in understanding decreasing female fertility and in the use of assisted reproductive technologies in human and farm animals…”
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Pairwise comparisons of ten porcine tissues identify differential transcriptional regulation at the gene, isoform, promoter and transcription start site level by Farajzadeh, Leila, Hornshøj, Henrik, Momeni, Jamal, Thomsen, Bo, Larsen, Knud, Hedegaard, Jakob, Bendixen, Christian, Madsen, Lone Bruhn

“…•Transcriptome sequencing yielded 223 mill porcine RNA-seq reads, and 59,000 transcribed locations.•Establishment of unique transcription profiles for ten…”
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Porcine UCHL1: genomic organization, chromosome localization and expression analysis by Larsen, Knud, Madsen, Lone Bruhn, Bendixen, Christian

“…The human UCHL1 gene encodes the ubiquitin C-terminal hydrolase UCHL1, which comprises more than 2% of total brain protein. UCHL1 is a component of the…”
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Molecular Cloning and Characterization of Porcine Na.sup.+/K.sup.+-ATPase Isoforms [alpha]1, [alpha]2, [alpha]3 and the ATP1A3 Promoter by Henriksen, Carina, Kjaer-Sorensen, Kasper, Einholm, Anja Pernille, Madsen, Lone Bruhn, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Vilsen, Bente, Larsen, Knud

“…Na.sup.+ /K.sup.+ -ATPase maintains electrochemical gradients of Na.sup.+ and K.sup.+ essential for a variety of cellular functions including neuronal…”
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Characterization of the porcine TOR1A gene: The first step towards generation of a pig model for dystonia by Henriksen, Carina, Madsen, Lone Bruhn, Bendixen, Christian, Larsen, Knud

“…The TOR1A (also named DYT1) gene encodes a protein, TorsinA, a member of the AAA+ superfamily of ATPases. The AAA+ proteins have diverse functions such as…”
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Porcine γ-synuclein: molecular cloning, expression analysis, chromosomal localization and functional expression by Frandsen, Pernille Munk, Madsen, Lone Bruhn, Bendixen, Christian, Larsen, Knud

“…The γ-synuclein protein is involved in breast carcinogenesis and has also been implicated in other forms of cancer and in ocular diseases. Furthermore,…”
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Porcine Parkin: Molecular cloning of PARK2 cDNA, expression analysis, and identification of a splicing variant by Bjerre, Ditte, Madsen, Lone Bruhn, Bendixen, Christian, Larsen, Knud

“…Parkin, encoded by the PARK2 gene, is an E3 ligase which functions as an integral component of the cytoplasmic ubiquitin/proteasomal protein degradation…”
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Molecular cloning, characterization and developmental expression of porcine β-synuclein by Larsen, Knud, Frandsen, Pernille Munk, Madsen, Lone Bruhn, Bendixen, Christian

“…The synuclein family includes three known proteins: α-synuclein, β-synuclein and γ-synuclein. β-Synuclein inhibits the aggregation of α-synuclein, a protein…”
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Molecular cloning, characterization and developmental expression of porcine [beta]-synuclein by Larsen, Knud, Frandsen, Pernille Munk, Madsen, Lone Bruhn, Bendixen, Christian

“…The synuclein family includes three known proteins: α-synuclein, β-synuclein and γ-synuclein. β-Synuclein inhibits the aggregation of α-synuclein, a protein…”
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Porcine g-synuclein: molecular cloning, expression analysis, chromosomal localization and functional expression by Frandsen, Pernille Munk, Madsen, Lone Bruhn, Bendixen, Christian, Larsen, Knud

“…The g-synuclein protein is involved in breast carcinogenesis and has also been implicated in other forms of cancer and in ocular diseases. Furthermore,…”
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