Search Results - "Madsen, Lars Siim"

Corticosteroid delivery using oral mucosa equivalents for the treatment of inflammatory mucosal diseases by Said, Zulfahmi, Murdoch, Craig, Hansen, Jens, Siim Madsen, Lars, Colley, Helen E.

“…Oral lichen planus (OLP) is an immune‐mediated disease of the oral mucosa with idiopathic aetiology. It is frequently treated with topical corticosteroids…”
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Oral lichen planus clinician reported outcome measure: Development, content validity, and further development by Brennan, Michael T., Riordain, Richeal Ni, Long‐Simpson, Leslie, Bissonnette, Caroline, Lizano, Marcela, Madsen, Lars Siim

“…Objective To establish and test a clinician‐reported outcome measure of oral lichen planus (OLP): OLP Investigator global assessment (IGA). Methods OLP IGA…”
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Novel Oral Lichen Planus Symptom Severity Measure for assessing patients’ daily symptom experience by Burke, Laurie B., Brennan, Michael T, Ni Riordain, Richeal, Madsen, Lars Siim

“…Objective A novel Oral Lichen Planus Symptom Severity Measure was developed as a clinical outcome assessment of the daily symptom experience of patients with…”
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Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial by Brennan, Michael T., Madsen, Lars Siim, Saunders, Deborah P., Napenas, Joel J., McCreary, Christine, Ni Riordain, Richeal, Pedersen, Anne Marie Lynge, Fedele, Stefano, Cook, Richard J., Abdelsayed, Rafik, Llopiz, Maria T., Sankar, Vidya, Ryan, Kevin, Culton, Donna A., Akhlef, Yousra, Castillo, Fausto, Fernandez, Inti, Jurge, Sabine, Kerr, Alexander R., McDuffie, Chad, McGaw, Tim, Mighell, Alan, Sollecito, Thomas P., Schlieve, Thomas, Carrozzo, Marco, Papas, Athena, Bengtsson, Thomas, Al‐Hashimi, Ibtisam, Burke, Laurie, Burkhart, Nancy W., Culshaw, Shauna, Desai, Bhavik, Hansen, Jens, Jensen, Pia, Menné, Torkil, Patel, Paras B., Thornhill, Martin, Treister, Nathaniel, Ruzicka, Thomas

“…Background Oral lichen planus (OLP) is a chronic inflammatory disorder of the oral mucosa. Currently there is no approved treatment for OLP. We report on the…”
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The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels by Bentzen, Bo Hjorth, Nardi, Antonio, Calloe, Kirstine, Madsen, Lars Siim, Olesen, Søren-Peter, Grunnet, Morten

“…Large-conductance Ca(2+)- and voltage-activated K(+) channels (Kca1.1/BK/MaxiK) are widely expressed ion channels. They provide a Ca(2+)-dependent feedback…”
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Blockade of Ca2+‐activated K+ channels in T cells: an option for the treatment of multiple sclerosis? by Madsen, Lars Siim, Christophersen, Palle, Olesen, Søren‐Peter

“…Voltage‐ and Ca2+‐dependent K+ channels in the membrane of both T and B lymphocytes are important for the cellular immune response. In the current issue of the…”
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Expanding Patient-Centered Outcome Measures in Oral Lichen Planus Management by BISSONNETTE, CAROLINE, LIZANO, MARCELA, RIORDAIN, RICHEAL NI, MADSEN, LARS SIIM, BRENNAN, MICHAEL T

“…Objectives: Oral lichen planus (OLP) is a common immune-mediated condition affecting the mucous membranes and skin with a prevalence of approximately 0.5% in…”
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New Investigator Global Assessment Scale in Lichen Planus: OLP IGA by BRENNAN, MICHAEL T, BISSONNETTE, CAROLINE, LIZANO, MARCELA, MADSEN, LARS SIIM, RIORDAIN, RICHELLE NI

“…Objectives: The Oral Lichen Planus Investigator Global Assessment (OLP IGA) outcome is a new disease specific measure assessing the severity of OLP. Based on…”
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Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease by Edmans, Jake G., Ollington, Bethany, Colley, Helen E., Santocildes-Romero, Martin E., Siim Madsen, Lars, Hatton, Paul V., Spain, Sebastian G., Murdoch, Craig

“…Chronic ulcerative oral mucosal inflammatory diseases, including oral lichen planus and recurrent aphthous stomatitis, are painful and highly prevalent, yet…”
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The Rivelin Patch—A New Treatment Strategy for Oral Lichen Planus by Ruzicka, Thomas, Seegräber, Marlene, Bieber, Thomas, Homey, Bernhard, Riordain, Richeal N.I., Madsen, Lars Siim, Hansen, Jens

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EFFICACY AND SAFETY OF A NOVEL MUCOADHESIVE CLOBETASOL PATCH FOR TREATMENT OF ORAL LICHEN PLANUS by Brennan, Michael T., Madsen, Lars Siim, Saunders, Deborah P., Napenas, Joel J., Riordain, Richeal Ni, Pedersen, Anne Marie Lynge, Fedele, Stefano, Cook, Richard J., Abdelsayed, Rafik, Sankar, Vidya, Ruzicka, Thomas

“…Oral lichen planus (OLP) is a chronic inflammatory disorder of the oral mucosa with no approved treatment. This was the first and largest global randomized,…”
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Novel Bilayer Mucoadhesive Patches for Delivery of Clobetasol-17-Propionate to the Oral Mucosa to Treat Oral Lichen Planus; an in Vitro and in Vivo Evaluation by Colley, Helen E., Said, Zulfahami, Santocildes-Romero, Martin E., Baker, Sarah R., D'Apice, Katie, Hansen, Jens, Madsen, Lars Siim, Thornhill, Martin H., Hatton, Paul V., Murdoch, Craig

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Blockade of Ca 2+ ‐activated K + channels in T cells: an option for the treatment of multiple sclerosis? by Madsen, Lars Siim, Christophersen, Palle, Olesen, Søren‐Peter

“…Abstract Voltage‐ and Ca 2+ ‐dependent K + channels in the membrane of both T and B lymphocytes are important for the cellular immune response. In the current…”
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Blockade of Ca super(2+)-activated K super(+) channels in T cells: an option for the treatment of multiple sclerosis? by Madsen, Lars Siim, Christophersen, Palle, Olesen, Soeren-Peter

“…Voltage-and Ca super(2+)-dependent K super(+) channels in the membrane of both T and B lymphocytes are important for the cellular immune response. In the…”
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Functional characterization of HLA-DRA1 0101/ DRB1 0401 molecules expressed in Drosophila melanogaster cells by Hansen, Bjarke Endel, Andersson, Ellen Christina, Madsen, Lars Siim, Engberg, Jan, Søndergaard, Leif, Svejgaard, Arne, Fugger, Lars

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Functional characterization of HLA‐DRA11 0101/ DRB1 0401 molecules expressed in Drosophila melanogaster cells by Hansen, Bjarke Endel, Andersson, Ellen Christina, Madsen, Lars Siim, Engberg, Jan, Søndergaard, Leif, Svejgaard, Arne, Fugger, Lars

“…: We have expressed the human MHC class II molecule, HLA‐DRA1*0101/‐DRB1*0401 (DRB1 *0401), in Drosophila melanogaster Schneider 2 cells under control of the…”
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