Search Results - "Madsen, Christian M."

Novel Insights From Human Studies on the Role of High-Density Lipoprotein in Mortality and Noncardiovascular Disease by Madsen, Christian M., Varbo, Anette, Nordestgaard, Børge G.

“…The vast majority of research about HDL (high-density lipoprotein) has for decades revolved around the possible role of HDL in atherosclerosis and its…”
Get full text

U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies by Madsen, Christian M, Varbo, Anette, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, Nordestgaard, Børge G

“…Abstract Aims Preclinical evidence has indicated that HDL may play an important role in the immune system; however, very little is known about the role of HDL…”
Get full text

Low-Grade Inflammation in the Association between Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis: A Study of More Than 115000 Individuals from the General Population by Hansen, Signe E J, Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…How mild-to-moderate hypertriglyceridemia (2-10 mmol/L; 177-886 mg/dL) potentially causes acute pancreatitis is unknown; however, cellular studies indicate…”
Get full text

Low HDL Cholesterol and High Risk of Autoimmune Disease: Two Population-Based Cohort Studies Including 117341 Individuals by Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…HDL is quantitatively the most important lipoprotein in most species and mechanistic evidence points toward a role for HDL in normal immune function. We tested…”
Get full text

Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis by Trinder, Mark, Wang, Yanan, Madsen, Christian M., Ponomarev, Tatjana, Bohunek, Lubos, Daisely, Brendan A., Julia Kong, HyeJin, Blauw, Lisanne L., Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Wurfel, Mark M., Russell, James A., Walley, Keith R., Rensen, Patrick C.N., Boyd, John H., Brunham, Liam R.

“…The high-density lipoprotein hypothesis of atherosclerosis has been challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors,…”
Get full text

Temporal trends in hip fracture incidence, mortality, and morbidity in Denmark from 1999 to 2012 by Jantzen, Christopher, Madsen, Christian M, Lauritzen, Jes B, Jørgensen, Henrik L

“…Background and purpose - While development in hip fracture incidence and mortality is well examined, none has yet looked at the temporal trends regarding…”
Get full text

Centenarian hip fracture patients: a nationwide population-based cohort study of 507 patients by Mosfeldt, Mathias, Madsen, Christian M, Lauritzen, Jes B, Jørgensen, Henrik L

“…Background and purpose - Several studies suggest a global increase of centenarians during the 21st century. We describe temporal trends of hip fracture…”
Get full text

Worldwide Prevalence of Familial Hypercholesterolemia: Meta-Analyses of 11 Million Subjects by Beheshti, Sabina O, Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…Despite the greater prevalence of familial hypercholesterolemia (FH) in subjects with ischemic heart disease (IHD), premature IHD, and severe…”
Get full text

Lipoprotein(a)-Lowering by 50 mg/dL (105 nmol/L) May Be Needed to Reduce Cardiovascular Disease 20% in Secondary Prevention: A Population-Based Study by Madsen, Christian M., Kamstrup, Pia R., Langsted, Anne, Varbo, Anette, Nordestgaard, Børge G.

“…OBJECTIVE:High Lp(a) (lipoprotein[a]) cause cardiovascular disease (CVD) in a primary prevention setting; however, it is debated whether high Lp(a) lead to…”
Get full text

Low Levels of Hemoglobin at Admission Are Associated With Increased 30-Day Mortality in Patients With Hip Fracture by Praetorius, Katrine, Madsen, Christian M., Abrahamsen, Bo, Jørgensen, Henrik L., Lauritzen, Jes B., Laulund, Anne Sofie B.

“…Introduction: Previous smaller studies suggest that anemia is a risk factor for mortality in patients with hip fracture. The purpose of this investigation was…”
Get full text

Unmet need for primary prevention in individuals with hypertriglyceridaemia not eligible for statin therapy according to European Society of Cardiology/European Atherosclerosis Society guidelines: a contemporary population-based study by Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…Abstract Aims To identify individuals at high risk of atherosclerotic cardiovascular disease (ASCVD), who are not definite statin eligible according to the…”
Get full text

Relationship of Familial Hypercholesterolemia and High Low-Density Lipoprotein Cholesterol to Ischemic Stroke: Copenhagen General Population Study by Beheshti, Sabina, Madsen, Christian M, Varbo, Anette, Benn, Marianne, Nordestgaard, Børge G

“…BACKGROUND:Familial hypercholesterolemia (FH) is a condition with very high concentrations of low-density lipoprotein (LDL) cholesterol and high risk of…”
Get full text

Is It Time for New Thinking About High-Density Lipoprotein? by Madsen, Christian M, Nordestgaard, Børge G

Get full text

Genetic Variants Associated With Increased Plasma Levels of Triglycerides, via Effects on the Lipoprotein Lipase Pathway, Increase Risk of Acute Pancreatitis by Hansen, Signe E.J., Madsen, Christian M., Varbo, Anette, Tybjærg-Hansen, Anne, Nordestgaard, Børge G.

“…Almost one third of adults in the West have increased plasma levels of triglycerides. Even mild to moderate hypertriglyceridemia (2–10 mmol/L or 177–886 mg/dL)…”
Get full text

Body Mass Index, Triglycerides, and Risk of Acute Pancreatitis: A Population-Based Study of 118 000 Individuals by Hansen, Signe E J, Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…Abstract Objective The incidence of acute pancreatitis is rising worldwide and currently no curative treatment exists. Clarification of preventable risk…”
Get full text

Novel Speed Test for Evaluation of Badminton-Specific Movements by Madsen, Christian M, Karlsen, Anders, Nybo, Lars

“…ABSTRACTMadsen, CM, Karlsen, A, and Nybo, L. Novel speed test for evaluation of badminton-specific movements. J Strength Cond Res 29(5)1203–1210, 2015—In this…”
Get full text

Neutrophil to lymphocyte ratio predicts cardiovascular events in people with type 2 diabetes: Post hoc analysis of the SUSTAIN 6 and PIONEER 6 cardiovascular outcomes trials by Verma, Subodh, Husain, Mansoor, Madsen, Christian M., Leiter, Lawrence A., Kuhlman, Anja Birk, Vilsbøll, Tina, Rasmussen, Søren, Libby, Peter

Get full text

How To Identify Familial Premature Myocardial Infarction: Comparing Approaches To Identify Familial Hypercholesterolemia by Beheshti, Sabina, Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…Abstract Context How best to identify families with premature myocardial infarction is unclear. Objective We compared approaches to identify familial premature…”
Get full text

Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies by Madsen, Christian M, Varbo, Anette, Nordestgaard, Børge G

“…High-density lipoprotein (HDL) cholesterol concentrations are inversely associated with cardiovascular disease and mortality across a range of concentrations,…”
Get full text

Excess mortality following hip fracture in patients with diabetes according to age: a nationwide population-based cohort study of 154,047 hip fracture patients by Madsen, Christian M, Jantzen, Christopher, Norring-Agerskov, Debbie, Vojdeman, Fie J, Abrahamsen, Bo, Lauritzen, Jes B, Jørgensen, Henrik L

“…to test the hypothesis that excess mortality conferred by diabetes following hip fracture decreases with advancing age. a nationwide population-based cohort…”
Get full text