Search Results - "Madrigal, J."

B cell regulation in cancer and anti-tumor immunity by Sarvaria, Anushruti, Madrigal, J Alejandro, Saudemont, Aurore

“…The balance between immune effector cells and immunosuppressive cells and how this regulates the tumor microenvironment has been well described. A significant…”
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HLA-B leader and survivorship after HLA-mismatched unrelated donor transplantation by Petersdorf, Effie W., Stevenson, Philip, Bengtsson, Mats, De Santis, Dianne, Dubois, Valerie, Gooley, Ted, Horowitz, Mary, Hsu, Katharine, Madrigal, J. Alejandro, Malkki, Mari, McKallor, Caroline, Morishima, Yasuo, Oudshoorn, Machteld, Spellman, Stephen R., Villard, Jean, Carrington, Mary

“…Hematopoietic cell transplantation (HCT) from HLA-mismatched unrelated donors can cure life-threatening blood disorders, but its success is limited by…”
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Climate warming enhances snow avalanche risk in the Western Himalayas by Ballesteros-Cánovas, J. A., Trappmann, D., Madrigal-González, J., Eckert, N., Stoffel, M.

“…Ongoing climate warming has been demonstrated to impact the cryosphere in the Indian Himalayas, with substantial consequences for the risk of disasters, human…”
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Umbilical Cord Blood Natural Killer Cells, Their Characteristics, and Potential Clinical Applications by Sarvaria, Anushruti, Jawdat, Dunia, Madrigal, J Alejandro, Saudemont, Aurore

“…Natural killer (NK) cells are lymphocytes of the innate immune system able to kill different targets such as cancer cells and virally infected cells without…”
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Advanced Cell Therapy: Beyond the last Frontier in the Treatment of Cancer. A Historical Perspective Emphasizing the Work of Nobel Prize Laureates by Madrigal, J Alejandro, de Chavez, Manuel Ruiz, Mayani, Hector

“…During the last five decades different therapies have been developed for the treatment of cancer, and as a result, patients can now live longer and better…”
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Innate immune receptor Toll-like receptor 4 signalling in neuropsychiatric diseases by García Bueno, B, Caso, J R, Madrigal, J L M, Leza, J C

“…The innate immunity is a stereotyped first line of defense against pathogens and unspecified damage signals. One of main actors of innate immunity are the…”
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HLA Typing for the Next Generation by Mayor, Neema P, Robinson, James, McWhinnie, Alasdair J M, Ranade, Swati, Eng, Kevin, Midwinter, William, Bultitude, Will P, Chin, Chen-Shan, Bowman, Brett, Marks, Patrick, Braund, Henny, Madrigal, J Alejandro, Latham, Katy, Marsh, Steven G E

“…Allele-level resolution data at primary HLA typing is the ideal for most histocompatibility testing laboratories. Many high-throughput molecular HLA typing…”
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Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study by Fleischhauer, Katharina, MD, Shaw, Bronwen E, Dr, Gooley, Theodore, Prof, Malkki, Mari, PhD, Bardy, Peter, MD, Bignon, Jean-Denis, MD, Dubois, Valérie, BSc, Horowitz, Mary M, Prof, Madrigal, J Alejandro, Prof, Morishima, Yasuo, Prof, Oudshoorn, Machteld, PhD, Ringden, Olle, Prof, Spellman, Stephen, MBS, Velardi, Andrea, Prof, Zino, Elisabetta, BSc, Petersdorf, Effie W, Prof

“…Summary Background The risks after unrelated-donor haemopoietic-cell transplantation with matched HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1 alleles between donor…”
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Cryopreservation has no effect on function of natural killer cells differentiated in vitro from umbilical cord blood CD34+ cells by Domogala, Anna, Madrigal, J. Alejandro, Saudemont, Aurore

“…Abstract Background aims Natural killer (NK) cells offer the potential for a powerful cellular immunotherapy because they can target malignant cells without…”
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A Phase II Study of Pembrolizumab in EGFR-Mutant, PD-L1+, Tyrosine Kinase Inhibitor Naïve Patients With Advanced NSCLC by Lisberg, A, Cummings, A, Goldman, J W, Bornazyan, K, Reese, N, Wang, T, Coluzzi, P, Ledezma, B, Mendenhall, M, Hunt, J, Wolf, B, Jones, B, Madrigal, J, Horton, J, Spiegel, M, Carroll, J, Gukasyan, J, Williams, T, Sauer, L, Wells, C, Hardy, A, Linares, P, Lim, C, Ma, L, Adame, C, Garon, Edward B

“…Despite the significant antitumor activity of pembrolizumab in NSCLC, clinical benefit has been less frequently observed in patients whose tumors harbor EGFR…”
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Enumerating regulatory T cells in cryopreserved umbilical cord blood samples using FOXP3 methylation specific quantitative PCR by Duggleby, Richard C, Tsang, Hoi Pat, Strange, Kathryn, McWhinnie, Alasdair, Lamikanra, Abigail A, Roberts, David J, Hernandez, Diana, Madrigal, J Alejandro, Danby, Robert D

“…Allogeneic haematopoietic cell transplantation (HCT) is a curative therapy for severe haematological disorders. However, it carries significant risk of…”
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Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation by Petersdorf, Effie W, Bengtsson, Mats, De Santis, Dianne, Dubois, Valerie, Fleischhauer, Katharina, Gooley, Ted, Horowitz, Mary, Madrigal, J Alejandro, Malkki, Mari, McKallor, Caroline, Morishima, Yasuo, Oudshoorn, Machteld, Spellman, Stephen R, Villard, Jean, Stevenson, Phil, Carrington, Mary

“…The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell…”
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Clinical Grade Regulatory CD4 + T Cells (Tregs): Moving Toward Cellular-Based Immunomodulatory Therapies by Duggleby, Richard, Danby, Robert David, Madrigal, J Alejandro, Saudemont, Aurore

“…Regulatory T cells (Tregs) are CD4 T cells that are key players of immune tolerance. They are powerful suppressor cells, able to impact the function of…”
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A LEGO Mindstorms NXT approach for teaching at Data Acquisition, Control Systems Engineering and Real-Time Systems undergraduate courses by Cruz-Martín, A., Fernández-Madrigal, J.A., Galindo, C., González-Jiménez, J., Stockmans-Daou, C., Blanco-Claraco, J.L.

“…LEGO Mindstorms NXT robots are being increasingly used in undergraduate courses, mostly in robotics-related subjects. But other engineering topics, like the…”
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Fire enhances changes in phosphorus (P) dynamics determining potential post-fire soil recovery in Mediterranean woodlands by Souza-Alonso, P., Prats, S. A., Merino, A., Guiomar, N., Guijarro, M., Madrigal, J.

“…Soil phosphorus (P), which is essential for ecosystem functioning, undergoes notable changes after fire. However, the extent to which fire characteristics…”
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Donation of peripheral blood stem cells to unrelated strangers: A thematic analysis by Billen, Annelies, Madrigal, J Alejandro, Scior, Katrina, Shaw, Bronwen E, Strydom, Andre

“…Donation of haematopoietic stem cells, either through bone marrow (BM) or peripheral blood stem cell (PBSC) collection, is a generally safe procedure for…”
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High‐resolution HLA allele and haplotype frequencies in majority and minority populations of Costa Rica and Nicaragua: Differential admixture proportions in neighboring countries by Arrieta‐Bolaños, E., Madrigal‐Sánchez, J. J., Stein, J. E., Órlich‐Pérez, P., Moreira‐Espinoza, M. J., Paredes‐Carias, E., Vanegas‐Padilla, Y., Salazar‐Sánchez, L., Madrigal, J. A., Marsh, S. G. E., Shaw, B. E.

“…The HLA system shows the most extensive polymorphism in the human genome. Allelic and haplotypic frequencies of HLA genes vary dramatically across human…”
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Hurdles in therapy with regulatory T cells by Trzonkowski, Piotr, Bacchetta, Rosa, Battaglia, Manuela, Berglund, David, Bohnenkamp, Hermann Richard, ten Brinke, Anja, Bushell, Andrew, Cools, Nathalie, Geissler, Edward K, Gregori, Silvia, Marieke van Ham, S, Hilkens, Catharien, Hutchinson, James A, Lombardi, Giovanna, Madrigal, J Alejandro, Marek-Trzonkowska, Natalia, Martinez-Caceres, Eva M, Roncarolo, Maria Grazia, Sanchez-Ramon, Silvia, Saudemont, Aurore, Sawitzki, Birgit

“…Improper activation of the immune system contributes to a variety of clinical conditions, including autoimmune and allergic diseases as well as solid organ and…”
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Assessing optical remote sensing for grave detection by Silván-Cárdenas, J.L., Caccavari-Garza, A., Quinto-Sánchez, M.E., Madrigal-Gómez, J.M., Coronado-Juárez, E., Quiroz-Suarez, D.

“…The application of an effective and ready-to-use tool for discovering clandestine graves is crucial for solving a number of cases where disappearance of people…”
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Functional Characterisation and Analysis of the Soluble NKG2D Ligand Repertoire Detected in Umbilical Cord Blood Plasma by Cox, Steven T, Danby, Robert, Hernandez, Diana, Laza-Briviesca, Raquel, Pearson, Hayley, Madrigal, J Alejandro, Saudemont, Aurore

“…We previously reported that cord blood plasma (CBP) contains significantly more soluble NKG2D ligands (sNKG2DLs), such as sMICB and sULBP1, than healthy adult…”
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