Search Results - "Madl, James E"

Manganese-Induced Neurotoxicity: The Role of Astroglial-Derived Nitric Oxide in Striatal Interneuron Degeneration by Liu, Xuhong, Sullivan, Kelly A., Madl, James E., Legare, Marie, Tjalkens, Ronald B.

“…Chronic exposure to excessive manganese (Mn) is the cause of a neurodegenerative movement disorder, termed manganism, resulting from degeneration of neurons…”
Get full text

Domoic acid-induced seizures in California sea lions (Zalophus californianus) are associated with neuroinflammatory brain injury by Kirkley, Kelly S., Madl, James E., Duncan, Colleen, Gulland, Frances M., Tjalkens, Ronald B.

“…•Domoic acid causes seizures in California sea lions (CSLs) similar to human epilepsy.•Oxidative stress and neuroinflammation are important in domoic acid…”
Get full text

Insulin and IGF-I prevent brain atrophy and DNA loss in diabetes by Šerbedžija, Predrag, Madl, James E, Ishii, Douglas N

“…Abstract The aim of this study was to identify factors that regulate the bulk of adult brain mass, and test the hypothesis that concomitantly reduced insulin…”
Get full text

Oxidative stress increases in retinas of dogs in acute glaucoma but not in chronic glaucoma by Chen, Thomas, Gionfriddo, Juliet R., Tai, Pei-Yi, Novakowski, Anna N., Alyahya, Khaleel, Madl, James E.

“…OBJECTIVE: To test the hypothesis that oxidative stress occurs early in the pathogenesis of glaucoma in dogs. ANIMALS: Sections from eight control retinas and…”
Get full text

Retinal ganglion cell distribution and visual acuity in alpacas (Vicugna pacos) by Wang, Hsiao-Hui, Gallagher, Shannon K., Byers, Stacey R., Madl, James E., Gionfriddo, Juliet R.

“…Objective To investigate the distribution of retinal ganglion cells (RGCs) and visual acuity in alpacas (Vicugna pacos) through Brn‐3a immunofluorescent…”
Get full text

α-Luminol prevents decreases in glutamate, glutathione, and glutamine synthetase in the retinas of glaucomatous DBA/2J mice by Gionfriddo, Juliet R, Freeman, Kate S, Groth, Allyson, Scofield, Virginia L, Alyahya, Khaleel, Madl, James E

“…To test the hypothesis that in DBA/2J mice, oxidative stress decreases glutamine synthetase (GS) levels resulting in a loss of neuronal glutamate and that the…”
Get full text

Loss of glutamine synthetase immunoreactivity from the retina in canine primary glaucoma by Chen, Chu-Te, Alyahya, Khaleel, Gionfriddo, Juliet R, Dubielzig, Richard R, Madl, James E

“…Changes in retinal glutamate distribution occur in primary glaucoma (PG) in dogs. Although the redistribution resembles that induced by ischemia, decreases in…”
Get full text

Retinal pigment epithelial damage, breakdown of the blood-retinal barrier, and retinal inflammation in dogs with primary glaucoma by Mangan, Brendan G., Al-Yahya, Khaleel, Chen, Chu-Te, Gionfriddo, Juliet R., Powell, Cynthia C., Dubielzig, Richard R., Ehrhart, Eugene J., Madl, James E.

“…Objective  This paper aims to determine if abnormalities of the retinal pigment epithelium (RPE) and retinal inflammation occur in primary glaucoma. Procedure …”
Get full text

Microvessel loss, vascular damage and glutamate redistribution in the retinas of dogs with primary glaucoma by Alyahya, Khaleel, Chen, Chu-Te, Mangan, Brendan G., Gionfriddo, Juliet R., Legare, Marie E., Dubielzig, Richard R., Madl, James E.

“…Objective  Vascular damage and ischemia‐like changes in glutamate distribution occur in primary glaucoma (PG) in dogs. We measured the microvessel density in…”
Get full text

Depletion of taurine and glutamate from damaged photoreceptors in the retinas of dogs with primary glaucoma by Madl, J.E, McIlnay, T.R, Powell, C.C, Gionfriddo, J.R

“…To determine whether taurine and glutamate contents are reduced in damaged photoreceptors in dogs with primary glaucoma (PG) in a manner consistent with an…”
Get full text

Effects of Delphinium alkaloids on neuromuscular transmission by Dobelis, P, Madl, J E, Pfister, J A, Manners, G D, Walrond, J P

“…The Delphinium alkaloids methyllycaconitine (MLA), nudicauline, 14-deacetylnudicauline (14-DN), barbinine, and deltaline were investigated for their effects on…”
Get more information

POLYPLOIDS AND SEX DETERMINATION IN CAENORHABDITIS ELEGANS by Madl, James E, Herman, Robert K

“…Tetraploid stocks of Caenorhabditis elegans var. Bristol carrying autosomal and X-linked markers have been produced. Tetraploid hermaphrodites fall into two…”
Get full text

Assessment of glutamate loss from the ganglion cell layer of young DBA/2J mice with glaucoma by Low, H.C, Gionfriddo, J.R, Madl, J.E

“…To determine whether glutamate contents are decreased in the ganglion cell layer (GCL) of retinas of DBA/2J mice with glaucoma, compared with unaffected…”
Get full text

Evaluation of glutamate loss from damaged retinal cells of dogs with primary glaucoma by McIllnay, T.R, Gionfriddo, J.R, Dubielzig, R.R, Powell, C.C, Madl, J.E

“…To determine whether retinal damage in dogs with primary glaucoma (PG) is consistent with ischemia-induced glutamate toxicosis. Retinal tissue sections from 25…”
Get full text

DUPLICATIONS IN CAENORHABDITIS ELEGANS by Herman, Robert K, Madl, James E, Kari, Claire K

“…Thirteen chromosomal duplications, all unlinked to their linkage of origin, have been identified following X-irradiation. Ten are X-chromosome duplications, of…”
Get full text

Co-localization of fixative-modified glutamate and glutaminase in neurons of the spinal trigeminal nucleus of the rat: an immunohistochemical and immunoradiochemical analysis by Magnusson, K R, Larson, A A, Madl, J E, Altschuler, R A, Beitz, A J

“…The spinal trigeminal nucleus (STN) is involved in processing orofacial sensory information, including tactile, thermal and nociceptive input, and relaying…”
Get more information