Search Results - "Madiwale, Shreyas"
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The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG
Published in Nature communications (21-09-2023)“…The ERG (ETS-related gene) transcription factor is linked to various types of cancer, including leukemia. However, the specific ERG domains and co-factors…”
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Classifying Medulloblastoma Subgroups Based on Small, Clinically Achievable Gene Sets
Published in Frontiers in oncology (10-06-2021)“…As treatment protocols for medulloblastoma (MB) are becoming subgroup-specific, means for reliably distinguishing between its subgroups are a timely need…”
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Clampdown of inflammation in aging and anticancer therapies by limiting upregulation and activation of GPCR, CXCR4
Published in npj aging and mechanisms of disease (30-08-2018)“…One of the major pathological outcomes of DNA damage during aging or anticancer therapy is enhanced inflammation. However, the underlying signaling mechanism…”
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ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells
Published in Blood (20-01-2022)“…Mixed-phenotype acute leukemia is a rare subtype of leukemia in which both myeloid and lymphoid markers are co-expressed on the same malignant cells. The…”
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AML-079: The PNT Domain of ERG Regulates Hematopoietic Stemness and is Required for the Maintenance of ERG-Induced Leukemia
Published in Clinical lymphoma, myeloma and leukemia (01-09-2020)“…The ETS transcription factor ERG has a crucial role in hematopoiesis. It is essential for hematopoietic stem cell maintenance and megakaryopoiesis. Increased…”
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AML-131 ERG: From a Fortuitous Discovery to Potential Treatment for AML
Published in Clinical lymphoma, myeloma and leukemia (01-10-2022)Get full text
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Poster: AML-131 ERG: From a Fortuitous Discovery to Potential Treatment for AML
Published in Clinical lymphoma, myeloma and leukemia (01-10-2022)Get full text
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