Search Results - "Madireddi, Priyanka"

Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer by Raynal, Noël J-M, Lee, Justin T, Wang, Youjun, Beaudry, Annie, Madireddi, Priyanka, Garriga, Judith, Malouf, Gabriel G, Dumont, Sarah, Dettman, Elisha J, Gharibyan, Vazganush, Ahmed, Saira, Chung, Woonbok, Childers, Wayne E, Abou-Gharbia, Magid, Henry, Ryan A, Andrews, Andrew J, Jelinek, Jaroslav, Cui, Ying, Baylin, Stephen B, Gill, Donald L, Issa, Jean-Pierre J

“…Targeting epigenetic pathways is a promising approach for cancer therapy. Here, we report on the unexpected finding that targeting calcium signaling can…”
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MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J., Chandramoorthy, Harish C., Irrinki, Krishna M., Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E., Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J. Kevin, Madesh, Muniswamy

“…The mitochondrial calcium uniporter (MCU) mediates calcium uptake by mitochondria and thus regulates cellular bioenergetics, but how MCU activity is modulated…”
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Abstract A017: Patient-reported experience related to aspects of quality of life after cystectomy from an exploratory focus group by Imran, Nida, Peters, Wesley, Fixler, Karen, Madireddi, Priyanka, Shea, Lisa M., Ireland, Andrea

“…Abstract Purpose: These exploratory focus groups examined patient experiences after having a cystectomy following bladder cancer. Methods: US individuals aged…”
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Colorectal Carcinomas With CpG Island Methylator Phenotype 1 Frequently Contain Mutations in Chromatin Regulators by Tahara, Tomomitsu, Yamamoto, Eiichiro, Madireddi, Priyanka, Suzuki, Hiromu, Maruyama, Reo, Chung, Woonbok, Garriga, Judith, Jelinek, Jaroslav, Yamano, Hiro-o, Sugai, Tamotsu, Kondo, Yutaka, Toyota, Minoru, Issa, Jean-Pierre J, Estécio, Marcos R.H

“…Background & Aims Subgroups of colorectal carcinomas (CRCs) characterized by DNA methylation anomalies are termed CpG island methylator phenotype (CIMP)1,…”
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Gadd45b deficiency promotes premature senescence and skin aging by Magimaidas, Andrew, Madireddi, Priyanka, Maifrede, Silvia, Mukherjee, Kaushiki, Hoffman, Barbara, Liebermann, Dan A

“…The GADD45 family of proteins functions as stress sensors in response to various physiological and environmental stressors. Here we show that primary mouse…”
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Abstract 4442: Very low methylation is a novel epigenetic regulatory mechanism in normal tissues and predisposes to hypermethylation in cancer by madireddi, priyanka, Jelinek, Jaroslav, Lee, Justin, Sato, Takahiro, Issa, Jean-Pierre

“…Abstract High level DNA methylation of promoter CpG Island (CGI) represses gene expression. However, low-level CGI methylation is usually not distinguished…”
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Abstract 5382: A DNMT3A-independent hypomethylator phenotype is a unifying epigenetic signature of AML with good risk cytogenetics by Kelly, Andrew D., Madzo, Jozef, Madireddi, Priyanka, Kropf, Patricia, Good, Charly R., Jelinek, Jaroslav, Issa, Jean-Pierre J.

“…Abstract Background: Acute myeloid leukemia (AML) causes the most leukemia-related deaths in the United States, and has frequent mutations in epigenetic…”
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Demethylator phenotypes in acute myeloid leukemia by Kelly, Andrew D., Madzo, Jozef, Madireddi, Priyanka, Kropf, Patricia, Good, Charly R., Jelinek, Jaroslav, Issa, Jean-Pierre J.

“…Acute myeloid leukemia (AML) often harbors mutations in epigenetic regulators, and also has frequent DNA hypermethylation, including the presence of CpG island…”
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Abstract 2954: Low level methylation (1-20%) or methylation seeds is a distinct epigenetic regulator of gene expression and is a strong predictor of methylation gains in AML and MDS patients by Madireddi, Priyanka, Jelinek, Jaroslav, Lee, Justin, Cesaroni, Matteo, Rodrigues, Rodrigo, Zhang, Yan, Issa, Jean-Pierre

“…Abstract DNA methylation is an important epigenetic regulator of tumour suppressor genes in several cancers and is an established target for therapy. Genome…”
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As"SIRT"ing the role of an epigenetic modifier in hematopoietic stem cell homeostasis by Magimaidas, Andrew, Badolia, Rachit, Madireddi, Priyanka, Bhavanasi, Dheeraj

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The role of cis- and trans-acting factors in regulation of DNA methylation by Madireddi, Priyanka

“…High level DNA methylation of promoter CpG islands (CGIs) represses gene expression. However, low-level CGI methylation is currently not distinguished from…”
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Corrigenda: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J, Chandramoorthy, Harish C, Irrinki, Krishna M, Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E, Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J Kevin, Madesh, Muniswamy

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Erratum: Corrigenda: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J., Chandramoorthy, Harish C., Irrinki, Krishna M., Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E., Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J. Kevin, Madesh, Muniswamy

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Corrigenda: MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J, Chandramoorthy, Harish C, Irrinki, Krishna M, Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E, Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J Kevin, Madesh, Muniswamy

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Correction: Corrigenda: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J., Chandramoorthy, Harish C., Irrinki, Krishna M., Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E., Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J. Kevin, Madesh, Muniswamy

“…Nat. Cell Biol. 14, 1336–1343 (2012); published online 25 November 2012; corrected after print 10 June 2015 In the version of this Letter originally published,…”
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Targeting Calcium Signaling To Induce Epigenetic Reactivation of Tumor Suppressor Genes in Cancer by Raynal, Noël J.-M., Lee, Justin T., Wang, Youjun, Beaudry, Annie, Madireddi, Priyanka, Garriga, Judith, Malouf, Gabriel, Dumont, Sarah, Dettman, Elisha J., Gharibyan, Vazganush, Ahmed, Saira, Chung, Woonbok, Childers, Wayne E., Abou-Gharbia, Magid, Henry, Ryan A., Andrews, Andrew J., Jelinek, Jaroslav, Cui, Ying, Baylin, Stephen B., Gill, Donald L., Issa, Jean-Pierre J.

“…Targeting epigenetic pathways is a promising approach for cancer therapy. Here, we report on the unexpected finding that targeting calcium signaling can…”
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MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J, Chandramoorthy, Harish C, Irrinki, Krishna M, Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E, Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J Kevin, Madesh, Muniswamy

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MCUR1 is an Essential Component of Mitochondrial Ca2+ Uptake that regulates Cellular Metabolism by Mallilankaraman, Karthik, Cardenas, Cesar, Doonan, Patrick, Chandramoorthy, Harish, Irrinki, Krishna, Golenar, Tunde, Csordas, Gyorgy, Madireddi, Priyanka, Yang, Jun, Miller, Russell, Koesar, Jill, Kaufman, Brett, Hajnoczky, Gyorgy, Foskett, Kevin James, Madesh, Muniswamy

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Erratum: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick J., Chandramoorthy, Harish C., Irrinki, Krishna M., Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E., Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J. Kevin, Madesh, Muniswamy

“…Nat. Cell Biol. 14, 1336–1343 (2012); published online 25th November 2012; corrected online 30th November 2012 In the version of this Letter that was…”
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MCUR1 is an essential component of mitochondrial [Ca.sup.2+] uptake that regulates cellular metabolism by Mallilankaraman, Karthik, Cardenas, Cesar, Doonan, Patrick J, Chandramoorthy, Harish C, Irrinki, Krishna M, Golenar, Tunde, Csordas, Gyorgy, Madireddi, Priyanka, Yang, Jun, Muller, Marioly, Miller, Russell, Kolesar, Jill E, Molgo, Jordi, Kaufman, Brett, Hajnoczky, Gyorgy, Foskett, J. Kevin, Madesh, Muniswamy

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