Search Results - "Madiraju, Murty"
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Modulation of Mycobacterium tuberculosis proliferation by MtrA, an essential two‐component response regulator
Published in Molecular microbiology (01-05-2006)“…Summary Paired two‐component regulatory systems consisting of a sensor kinase and a response regulator are the major means by which bacteria sense and respond…”
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Interference of Mycobacterium tuberculosis cell division by Rv2719c, a cell wall hydrolase
Published in Molecular microbiology (01-10-2006)“…Summary The genetic factors responsible for the regulation of cell division in Mycobacterium tuberculosis are largely unknown. We showed that exposure of M…”
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Mycobacterium tuberculosis Cells Growing in Macrophages Are Filamentous and Deficient in FtsZ Rings
Published in Journal of Bacteriology (01-03-2006)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mycobacterium tuberculosis oriC sequestration by MtrA response regulator
Published in Molecular microbiology (01-10-2015)“…Summary The regulators of Mycobacterium tuberculosis DNA replication are largely unknown. Here, we demonstrate that in synchronously replicating M…”
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MtrA Response Regulator Controls Cell Division and Cell Wall Metabolism and Affects Susceptibility of Mycobacteria to the First Line Antituberculosis Drugs
Published in Frontiers in microbiology (23-11-2018)“…The biological processes regulated by the essential response regulator MtrA and the growth conditions promoting its activation in , a slow grower and pathogen,…”
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6
The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides
Published in PLoS pathogens (01-07-2009)“…The well-recognized phospholipids (PLs) of Mycobacterium tuberculosis (Mtb) include several acidic species such as phosphatidylglycerol (PG), cardiolipin,…”
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Control of CydB and GltA1 expression by the SenX3 RegX3 two component regulatory system of Mycobacterium tuberculosis
Published in PloS one (16-06-2011)“…Two component regulatory systems are used widely by bacteria to coordinate changes in global gene expression profiles in response to environmental signals. The…”
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8
Septal Localization of the Mycobacterium tuberculosis MtrB Sensor Kinase Promotes MtrA Regulon Expression
Published in The Journal of biological chemistry (06-07-2012)“…The mechanisms responsible for activation of the MtrAB two-component regulatory signal transduction system, which includes sensor kinase MtrB and response…”
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Mycobacterium tuberculosis MtrB Sensor Kinase Interactions with FtsI and Wag31 Proteins Reveal a Role for MtrB Distinct from That Regulating MtrA Activities
Published in Journal of bacteriology (01-12-2014)“…The septal association of Mycobacterium tuberculosis MtrB, the kinase partner of the MtrAB two-component signal transduction system, is necessary for the…”
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10
Mycobacterium tuberculosis Origin of Replication and the Promoter for Immunodominant Secreted Antigen 85B Are the Targets of MtrA, the Essential Response Regulator
Published in The Journal of biological chemistry (21-05-2010)“…Efficient proliferation of Mycobacterium tuberculosis (Mtb) inside macrophage requires that the essential response regulator MtrA be optimally phosphorylated…”
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Escherichia coli RecO Protein Anneals ssDNA Complexed with Its Cognate ssDNA-Binding Protein: A Common Step in Genetic Recombination
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2002)“…We present biochemical evidence for the functional similarity of Escherichia coli RecO protein and bacteriophage T4 UvsY protein to eukaryotic Rad52 protein…”
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The intrinsic ATPase activity of Mycobacterium tuberculosis DnaA promotes rapid oligomerization of DnaA on oriC
Published in Molecular microbiology (01-03-2006)“…Summary Oligomerization of the initiator protein, DnaA, on the origin of replication (oriC) is crucial for initiation of DNA replication. Studies in…”
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13
RNase HI Is Essential for Survival of Mycobacterium smegmatis
Published in PloS one (12-05-2015)“…RNases H are involved in the removal of RNA from RNA/DNA hybrids. Type I RNases H are thought to recognize and cleave the RNA/DNA duplex when at least four…”
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Mycobacterium tuberculosis ClpX interacts with FtsZ and interferes with FtsZ assembly
Published in PloS one (06-07-2010)“…FtsZ assembly at the midcell division site in the form of a Z-ring is crucial for initiation of the cell division process in eubacteria. It is largely unknown…”
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15
Synchronous replication initiation in novel Mycobacterium tuberculosis dnaA cold-sensitive mutants
Published in Molecular microbiology (01-01-2009)“…The genetic aspects of oriC replication initiation in Mycobacterium tuberculosis are largely unknown. A two-step genetic screen was utilized for isolating M…”
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Evaluation of two different dendritic cell preparations with BCG reactivity
Published in Archives of biological sciences (2016)“…Dendritic cells (DCs) play a key-role in the immune response against intracellular bacterial pathogens, including mycobacteria. Monocyte-derived dendritic…”
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17
Alterations in phospholipid catabolism in Mycobacterium tuberculosis lysX mutant
Published in Frontiers in cellular and infection microbiology (11-02-2011)“…Mycobacterium tuberculosis lysX mutant, defective for production of lysinylated phosphatidylglycerol (L-PG), is sensitive to cationic antimicrobial peptides,…”
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18
Mycobacterium tuberculosis MtrAY102C is a gain-of-function mutant that potentially acts as a constitutively active protein
Published in Tuberculosis (Edinburgh, Scotland) (01-12-2013)“…Abstract The MtrAB histidine-aspartate signal transduction of mycobacteria includes the response regulator MtrA and sensor kinase MtrB. We recently showed that…”
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Localization of acidic phospholipid cardiolipin and DnaA in mycobacteria
Published in Tuberculosis (Edinburgh, Scotland) (01-12-2011)“…Summary Acidic phospholipids such as cardiolipin (CL) have been shown to modulate Mycobacterium tuberculosis ( Mtb ) DnaA interactions with ATP. In the present…”
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Facilitation of Dissociation Reaction of Nucleotides Bound to Mycobacterium tuberculosis DnaA
Published in Journal of biochemistry (Tokyo) (01-06-2008)“…Acidic phospholipids have been shown to promote dissociation of bound nucleotides from Mycobacterium tuberculosis DnaA (DnaATB) purified under denaturing…”
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