Search Results - "Madhankumar, Achuthamangalam B."

Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms by Ravi, Vagisha, Madhankumar, Achuthamangalam B, Abraham, Thomas, Slagle-Webb, Becky, Connor, James R

“…Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival…”
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Exosomes impact survival to radiation exposure in cell line models of nervous system cancer by Mrowczynski, Oliver D, Madhankumar, Achuthamangalam B, Sundstrom, Jeffrey M, Zhao, Yuanjun, Kawasawa, Yuka Imamura, Slagle-Webb, Becky, Mau, Christine, Payne, Russell A, Rizk, Elias B, Zacharia, Brad E, Connor, James R

“…Radiation is utilized in the therapy of more than 50% of cancer patients. Unfortunately, many malignancies become resistant to radiation over time. We…”
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MRI contrast agent for targeting glioma: interleukin-13 labeled liposome encapsulating gadolinium-DTPA by Liu, Xiaoli, Madhankumar, Achuthamangalam B, Miller, Patti A, Duck, Kari A, Hafenstein, Susan, Rizk, Elias, Slagle-Webb, Becky, Sheehan, Jonas M, Connor, James R, Yang, Qing X

“…Detection of glioma with MRI contrast agent is limited to cases in which the blood-brain barrier (BBB) is compromised as contrast agents cannot cross the BBB…”
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Efficacy of interleukin-13 receptor–targeted liposomal doxorubicin in the intracranial brain tumor model by Achuthamangalam B. Madhankumar, Becky Slagle-Webb, Xinsheng Wang, Qing X. Yang, David A. Antonetti, Patti A. Miller, Jonas M. Sheehan, James R. Connor

“…Human glioblastoma tumors selectively express receptors for interleukin 13 (IL-13). In a previous study, we showed that liposomes, when conjugated with IL-13,…”
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Tumor Targeted Delivery of an Anti‐Cancer Therapeutic: An In Vitro and In Vivo Evaluation by Kang, You Jung, Holley, Claire K., Abidian, Mohammad Reza, Madhankumar, Achuthamangalam B., Connor, James, Majd, Sheereen

“…The limited effectiveness of current therapeutics against malignant brain gliomas has led to an urgent need for development of new formulations against these…”
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MLN8237 treatment in an orthoxenograft murine model for malignant peripheral nerve sheath tumors by Payne, Russell, Mrowczynski, Oliver D, Slagle-Webb, Becky, Bourcier, Alexandre, Mau, Christine, Aregawi, Dawit, Madhankumar, Achuthamangalam B, Lee, Sang Y, Harbaugh, Kimberly, Connor, James, Rizk, Elias B

“…Malignant peripheral nerve sheath tumors (MPNSTs) are soft-tissue sarcomas arising from peripheral nerves. MPNSTs have increased expression of the oncogene…”
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Targeting IL-13Rα2 for effective treatment of malignant peripheral nerve sheath tumors in mouse models by Mrowczynski, Oliver D., Payne, Russell A., Bourcier, Alexandre J., Mau, Christine Y., Slagle-Webb, Becky, Shenoy, Ganesh, Madhankumar, Achuthamangalam B., Abramson, Stephan B., Wolfe, Darren, Harbaugh, Kimberly S., Rizk, Elias B., Connor, James R.

“…Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas that harbor a high potential for metastasis and have a devastating…”
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Liposomal delivery of ferritin heavy chain 1 by Ravi, Vagisha, Madhankumar, Achuthamangalam B, Abraham, Thomas, Slagle-Webb, Becky, Connor, James R

“…Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival…”
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Biodegradable Nanoparticles: Tumor Targeted Delivery of an Anti‐Cancer Therapeutic: An In Vitro and In Vivo Evaluation (Adv. Healthcare Mater. 2/2021) by Kang, You Jung, Holley, Claire K., Abidian, Mohammad Reza, Madhankumar, Achuthamangalam B., Connor, James, Majd, Sheereen

“…This cover art represents a new anti‐cancer nanoformulation that targets the brain glioma tumors, offering a potential treatment for these aggressive tumors…”
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Abstract 745: Interleukin-13 conjugated quantum dots to identify glioma initiating cells and exosomes by Madhankumar, Achuthamangalam B., Mrowczynski, Oliver, Zacharia, Brad, Glantz, Michael, Xu, Lichong, Webb, Becky, Siedlecki, Christopher, Mintz, Akiva, Connor, James R.

“…High grade brain tumors like glioblastoma multiforme (GBM) and certain other brain metastatic cancers possess high tumor invasive and infiltrating properties…”
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Targeting IL-13Rα2 for effective treatment of malignant peripheral nerve sheath tumors in mouse models by Mrowczynski, Oliver D, Payne, Russell A, Bourcier, Alexandre J, Mau, Christine Y, Slagle-Webb, Becky, Shenoy, Ganesh, Madhankumar, Achuthamangalam B, Abramson, Stephan B, Wolfe, Darren, Harbaugh, Kimberly S, Rizk, Elias B, Connor, James R

“…Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas that harbor a high potential for metastasis and have a devastating…”
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Abstract 5521: IL13 linked lipsomal doxorubicin for malignant peripheral nerve sheath tumors by Madhankumar, Achuthamangalam B., Slagle-Webb, Becky, Park, Annie, Klinger, Marianne, Pang, Min, Harbaugh, Kimberly, Sheehan, Jonas M., Connor, James R.

“…We have previously demonstrated the therapeutic effect of interleukin-13 (IL13) linked liposomal doxorubicin (IL13LDXR) on glioma tumors. These tumors…”
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