Search Results - "Madhani, H.D"

Histone H3 Lysine 36 Methylation Antagonizes Silencing in Saccharomyces cerevisiae Independently of the Rpd3S Histone Deacetylase Complex by Tompa, R, Madhani, H.D

“…In yeast, methylation of histone H3 on lysine 36 (H3-K36) is catalyzed by the NSD1 leukemia oncoprotein homolog Set2. The histone deacetylase complex Rpd3S is…”
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Combinatorial control required for the specificity of yeast MAPK signaling by Madhani, H.D. (Whitehead Institute for Biomedical Research, Cambridge, MA.), Fink, G.R

“…In yeast, an overlapping set of mitogen-activated protein kinase (MAPK) signaling components controls mating, haploid invasion, and pseudohyphal development…”
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The riddle of MAP kinase signaling specificity by Madhani, Hiten D, Fink, Gerald R

“…Cells encounter an enormous variety of signals in their environments and must respond to each stimulus appropriately with changes in their genetic programs…”
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Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor by Kung, C, Kenski, D.M, Dickerson, S.H, Howson, R.W, Kuyper, L.F, Madhani, H.D, Shokat, K.M

“…The identification of the kinase or kinases targeted by protein kinase inhibitors is a critical challenge in validating their use as therapeutic agents or…”
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Genetic interactions between the yeast RNA helicase homolog Prp16 and spliceosomal snRNAs identify candidate ligands for the Prp16 RNA-dependent ATPase by Madhani, H.D, Guthrie, C

“…Pre-mRNA splicing occurs in a large and dynamic ribonucleoprotein complex, the spliceosome. Several protein factors involved in splicing are homologous to a…”
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