Search Results - "Madgula, Vamsi L. M"

Intestinal and blood-brain barrier permeability of ginkgolides and bilobalide: in vitro and in vivo approaches by Madgula, Vamsi L M, Avula, Bharathi, Yu, Young-Beob, Wang, Yan-Hong, Tchantchou, Flaubert, Fisher, Scott, Luo, Yuan, Khan, Ikhlas A, Khan, Shabana I

“…In this study intestinal and blood-brain barrier (BBB) permeability of ginkgolides A, B, C, J and bilobalide, isolated from Ginkgo biloba (Ginkgoaceae), was…”
Get more information

Liquid Chromatography-Tandem Mass Spectrometry Analysis of Urine Specimens for K2 (JWH-018) Metabolites by ElSohly, Mahmoud A., Gul, Waseem, ElSohly, Kareem M., Murphy, Timothy P., Madgula, Vamsi L.M., Khan, Shabana I.

“…Marijuana is the most widely used drug of abuse all over the world. The major active constituent of the drug is Δ9-tetrahydrocannabinol (Δ9-THC). Δ9-THC exerts…”
Get full text

Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson’s Disease and Depression by Basu, Sujay, Barawkar, Dinesh A, Ramdas, Vidya, Naykodi, Minakshi, Shejul, Yogesh D, Patel, Meena, Thorat, Sachin, Panmand, Anil, Kashinath, K, Bonagiri, Rajesh, Prasad, Vandna, Bhat, Ganesh, Quraishi, Azfar, Chaudhary, Sumit, Magdum, Amol, Meru, Ashwinkumar V, Ghosh, Indraneel, Bhamidipati, Ravi K, Raje, Amol A, Madgula, Vamsi L. M, De, Siddhartha, Rouduri, Sreekanth R, Palle, Venkata P, Chugh, Anita, Hariharan, Narayanan, Mookhtiar, Kasim A

“…Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinson’s disease treatment that is under development. Earlier we had reported…”
Get full text

Alkaloids and saponins as cytochrome P450 inhibitors from blue cohosh (Caulophyllum thalictroides) in an in vitro assay by Madgula, Vamsi L M, Ali, Zulfiqar, Smillie, Troy, Khan, Ikhlas A, Walker, Larry A, Khan, Shabana I

“…Blue cohosh, Caulophyllum thalictroides (L.) Michx. is a popular herb, roots and rhizomes of which have been extensively used for women's health. Alkaloids and…”
Get more information

Evaluation of separate role of intestine and liver in first pass metabolism of budesonide in rat by Raje, Amol A., Deshpande, Radni D., Pathade, Vishal V., Mahajan, Vallabh, Joshi, Kaushal, Tambe, Ashwini, Jinugu, Ramana, Madgula, Vamsi L. M., Gaur, Ashwani, Kandikere, Vishwottam, Patil, Chandragouda R., Mookhtiar, Kasim A.

“…1. Budesonide, a potent topical corticosteroid, reported to have low oral bioavailability in mice, rat, dog and human due to rapid first pass metabolism…”
Get full text

Discovery of Potent and Selective A 2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression by Basu, Sujay, Barawkar, Dinesh A, Ramdas, Vidya, Naykodi, Minakshi, Shejul, Yogesh D, Patel, Meena, Thorat, Sachin, Panmand, Anil, Kashinath, K, Bonagiri, Rajesh, Prasad, Vandna, Bhat, Ganesh, Quraishi, Azfar, Chaudhary, Sumit, Magdum, Amol, Meru, Ashwinkumar V, Ghosh, Indraneel, Bhamidipati, Ravi K, Raje, Amol A, Madgula, Vamsi L M, De, Siddhartha, Rouduri, Sreekanth R, Palle, Venkata P, Chugh, Anita, Hariharan, Narayanan, Mookhtiar, Kasim A

“…Adenosine A receptor (A AdoR) antagonism is a nondopaminergic approach to Parkinson's disease treatment that is under development. Earlier we had reported the…”
Get full text

Bioavailability, pharmacokinetics, and tissue distribution of the oxypregnane steroidal glycoside P57AS3 (P57) from Hoodia gordonii in mouse model by Madgula, Vamsi L M, Ashfaq, Mohammad K, Wang, Yan-Hong, Avula, Bharathi, Khan, Ikhlas A, Walker, Larry A, Khan, Shabana I

“…P57AS3 (P57), an oxypregnane steroidal glycoside, is known to be responsible for the appetite suppressing activity of HOODIA GORDONII, a dietary supplement…”
Get more information

Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - an in-vitro model of intestinal transport by Madgula, Vamsi L. M., Avula, Bharathi, Choi, Young W., Pullela, Srinivas V., Khan, Ikhlas A., Walker, Larry A., Khan, Shabana I.

“…We have determined the intestinal transport of Schisandra chinensis extract and its lignans (gomisin A, gomisin N and schisandrin C) in the Caco‐2 cell…”
Get full text

Transport of decursin and decursinol angelate across Caco-2 and MDR-MDCK cell monolayers: in vitro models for intestinal and blood-brain barrier permeability by Madgula, Vamsi L, Avula, Bharathi, Reddy V L, Niranjan, Khan, Ikhlas A, Khan, Shabana I

“…Decursin (DE) and decursinol angelate (DA) were isolated from the roots of Angelica gigas (Apiaceae) and purified by HPLC. DE and DA have been reported to…”
Get more information

In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes by Madgula, Vamsi L M, Avula, Bharathi, Pawar, Rahul S, Shukla, Yatin J, Khan, Ikhlas A, Walker, Larry A, Khan, Shabana I

“…Hoodia gordonii, a succulent cactus-like plant growing in South Africa, has been used in traditional medicine for its appetite suppressant properties. Its use…”
Get more information