Search Results - "Madern, Jerre M"

4‑Thioribose Analogues of Adenosine Diphosphate Ribose (ADPr) Peptides by Madern, Jerre M., Voorneveld, Jim, Rack, Johannes G. M., Kistemaker, Hans A. V., Ahel, Ivan, van der Marel, Gijsbert A., Codée, Jeroen D. C., Filippov, Dmitri V.

“…Adenosine diphosphate (ADP) ribosylation is an important post-translational modification (PTM) that plays a role in a wide variety of cellular processes. To…”
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Furanosyl Oxocarbenium Ion Conformational Energy Landscape Maps as a Tool to Study the Glycosylation Stereoselectivity of 2‐Azidofuranoses, 2‐Fluorofuranoses and Methyl Furanosyl Uronates by van der Vorm, Stefan, Hansen, Thomas, van Rijssel, Erwin R., Dekkers, Rolf, Madern, Jerre M., Overkleeft, Herman S., Filippov, Dmitri V., van der Marel, Gijsbert A., Codée, Jeroen D. C.

“…The 3D shape of glycosyl oxocarbenium ions determines their stability and reactivity and the stereochemical course of SN1 reactions taking place on these…”
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Synthesis, Reactivity, and Stereoselectivity of 4‑Thiofuranosides by Madern, Jerre M, Hansen, Thomas, van Rijssel, Erwin R, Kistemaker, Hans A.V, van der Vorm, Stefan, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V, Codée, Jeroen D.C

“…Thiosugars, sugars that have their endocyclic oxygen substituted for a sulfur atom, have been used as stable bioisosteres of naturally occurring glycans…”
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Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC by Madern, Jerre M., Kim, Robbert Q., Misra, Mohit, Dikic, Ivan, Zhang, Yong, Ovaa, Huib, Codée, Jeroen D. C., Filippov, Dmitri V., Heden van Noort, Gerbrand J.

“…Stable NAD+ analogues carrying single atom substitutions in either the furanose ring or the nicotinamide part have proven their value as inhibitors for…”
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Cover Feature: Furanosyl Oxocarbenium Ion Conformational Energy Landscape Maps as a Tool to Study the Glycosylation Stereoselectivity of 2‐Azidofuranoses, 2‐Fluorofuranoses and Methyl Furanosyl Uronates (Chem. Eur. J. 29/2019) by van der Vorm, Stefan, Hansen, Thomas, van Rijssel, Erwin R., Dekkers, Rolf, Madern, Jerre M., Overkleeft, Herman S., Filippov, Dmitri V., van der Marel, Gijsbert A., Codée, Jeroen D. C.

“…Energy maps of the full conformational space of 5‐membered ring glycosyl oxocarbenium ions have been generated to probe the stereoelectronic effects of…”
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