Search Results - "Madelaine, Romain"
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Genetic deciphering of the antagonistic activities of the melanin-concentrating hormone and melanocortin pathways in skin pigmentation
Published in PLoS genetics (10-12-2020)“…The genetic origin of human skin pigmentation remains an open question in biology. Several skin disorders and diseases originate from mutations in conserved…”
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2
Endogenous retinal neural stem cell reprogramming for neuronal regeneration
Published in Neural regeneration research (01-11-2017)“…In humans, optic nerve injuries and associated neurodegenerative diseases are often followed by perma- nent vision loss. Consequently, an important challenge…”
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3
MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis
Published in Cell reports (Cambridge) (15-08-2017)“…In the developing brain, neurons expressing VEGF-A and blood vessels grow in close apposition, but many of the molecular pathways regulating neuronal VEGF-A…”
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A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human
Published in Nucleic acids research (20-04-2018)“…Abstract Thousands of human disease-associated single nucleotide polymorphisms (SNPs) lie in the non-coding genome, but only a handful have been demonstrated…”
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5
Cell-type heterogeneity in the early zebrafish olfactory epithelium is generated from progenitors within preplacodal ectoderm
Published in eLife (02-01-2018)“…The zebrafish olfactory epithelium comprises a variety of neuronal populations, which are thought to have distinct embryonic origins. For instance, while…”
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Habenular Neurogenesis in Zebrafish Is Regulated by a Hedgehog, Pax6 Proneural Gene Cascade
Published in PloS one (07-07-2016)“…The habenulae are highly conserved nuclei in the dorsal diencephalon that connect the forebrain to the midbrain and hindbrain. These nuclei have been…”
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A cluster of non-redundant Ngn1 binding sites is required for regulation of deltaA expression in zebrafish
Published in Developmental biology (01-02-2011)“…Proneural genes encode bHLH transcription factors that are key regulator of neurogenesis in both vertebrates and invertebrates. How these transcription factors…”
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Partially redundant proneural function reveals the importance of timing during zebrafish olfactory neurogenesis
Published in Development (Cambridge) (01-11-2011)“…Little is known about proneural gene function during olfactory neurogenesis in zebrafish. Here, we show that the zebrafish Atonal genes neurogenin1 (neurog1)…”
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Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors
Published in PloS one (02-03-2017)“…The development of functional peripheral ganglia requires a balance of specification of both neuronal and glial components. In the developing dorsal root…”
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10
Interhemispheric asymmetry of olfactory input-dependent neuronal specification in the adult brain
Published in Nature neuroscience (01-07-2013)“…The authors identify a hemispheric asymmetry in neurogenesis in adult zebrafish. This asymmetry could be reversed by olfactory sensory deprivation or…”
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11
Neural signatures of sleep in zebrafish
Published in Nature (London) (01-07-2019)“…Slow-wave sleep and rapid eye movement (or paradoxical) sleep have been found in mammals, birds and lizards, but it is unclear whether these neuronal…”
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Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development
Published in Development (Cambridge) (21-12-2020)“…Sense organs acquire their distinctive shapes concomitantly with the differentiation of sensory cells and neurons necessary for their function. Although our…”
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13
Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells
Published in The Journal of neuroscience (09-06-2010)“…The limited generation of neurons during adulthood is controlled by a balance between quiescence and recruitment of neural stem cells (NSCs). We use here the…”
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14
The hypothalamic NPVF circuit modulates ventral raphe activity during nociception
Published in Scientific reports (31-01-2017)“…RFamide neuropeptide VF (NPVF) is expressed by neurons in the hypothalamus and has been implicated in nociception, but the circuit mechanisms remain…”
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15
Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development
Published in Development (Cambridge) (01-01-2020)“…Sense organs acquire their distinctive shapes concomitantly with the differentiation of sensory cells and neurons necessary for their function. While our…”
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