Search Results - "Madegowda, Mahendra"

Dithiane Based Boronic Acid as a Carbohydrate Sensor in an Aqueous Solution at pH 7.5: Theoretical and Experimental Approach by Revanna, Bhavya Nelligere, Madegowda, Mahendra

“…Carbohydrate sensing in an aqueous solution remains a very challenging area of interest. Using the idea of covalent reversible interaction between boronic…”
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Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells by Kim, Na Young, Vishwanath, Divakar, Xi, Zhang, Nagaraja, Omantheswara, Swamynayaka, Ananda, Kumar Harish, Keshav, Basappa, Shreeja, Madegowda, Mahendra, Pandey, Vijay, Sethi, Gautam, Lobie, Peter E, Ahn, Kwang Seok, Basappa, Basappa

“…Human epidermal growth factor receptor 2 (HER2)-positive breast cancer exhibits early relapses, poor prognoses, and high recurrence rates. Herein, a…”
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Zinc chloride catalyzed multicomponent synthesis of pyrazolopyridocoumarin scaffolds by Shamala, Devadas, Shivashankar, Kalegowda, Chandra, Mahendra, Madegowda

“…An efficient synthesis of a series of pyrazolopyridocoumarins is reported by condensation of 4-hydroxycoumarin, benzaldehydes and 1-alkyl-5-amino-pyrazoles in…”
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Development of 1-(4-(Substituted)piperazin-1-yl)-2-((2-((4-methoxybenzyl)thio)pyrimidin-4-yl)oxy)ethanones That Target Poly (ADP-Ribose) Polymerase in Human Breast Cancer Cells by Deveshegowda, Suresha N, Metri, Prashant K, Shivakumar, Rashmi, Yang, Ji-Rui, Rangappa, Shobith, Swamynayaka, Ananda, Shanmugam, Muthu K, Nagaraja, Omantheswara, Madegowda, Mahendra, Babu Shubha, Priya, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Pandey, Vijay, Ahn, Kwang Seok, Lobie, Peter E, Basappa, Basappa

“…A number of uracil amides cleave poly (ADP-ribose) polymerase and therefore novel thiouracil amide compounds were synthesized and screened for the loss of cell…”
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Discovery of oxazine-linked pyrimidine as an inhibitor of breast cancer growth and metastasis by abrogating NF-κB activation by Yuan, Jie, Narasimhachar, Bhanuprakash C, Ravish, Akshay, Yang, Li, Zhang, Hua, Wang, Qun, Li, Zhi, Huang, Jun, Wang, Bei, Wang, Geng, Kumar Harish, Keshav, Chinnathambi, Arunachalam, Govindasamy, Chandramohan, Madegowda, Mahendra, Basappa, Basappa

“…Nuclear factor kappa (NF-κB) plays a key role in cancer cell proliferation; thus, small molecule inhibitors of NF-κB activity can effectively inhibit breast…”
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Investigation of NPB Analogs That Target Phosphorylation of BAD-Ser99 in Human Mammary Carcinoma Cells by Girimanchanaika, Swamy Savvemala, Dukanya, Dukanya, Swamynayaka, Ananda, Govindachar, Divya Maldepalli, Madegowda, Mahendra, Periyasamy, Ganga, Rangappa, Kanchugarakoppal Subbegowda, Pandey, Vijay, Lobie, Peter E, Basappa, Basappa

“…The design and development of a small molecule named NPB [3-{(4(2,3-dichlorophenyl)piperazin-1-yl}{2-hydroxyphenyl)methyl}-N-cyclopentylbenzamide], which…”
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Para‐tertiary butyl catechol (PTBC), an industrial antioxidant induces human platelet apoptosis by Vishalakshi, Gopalapura J., NaveenKumar, Somanathapura K., Hemshekhar, Mahadevappa, Mahendra, Madegowda, Kemparaju, Kempaiah, Girish, Kesturu S.

“…The catecholic derivative para‐tertiary butyl catechol (PTBC) is a conventional antioxidant and polymerization inhibitor, which exhibits melanocytotoxic…”
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Oxazine drug-seed induces paraptosis and apoptosis through reactive oxygen species/JNK pathway in human breast cancer cells by Kim, Na Young, Dukanya, Dukanya, Sethi, Gautam, Girimanchanaika, Swamy S, Yang, Jirui, Nagaraja, Omantheswara, Swamynayaka, Ananda, Vishwanath, Divakar, Venkantesha, Keerthikumara, Basappa, Shreeja, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Madegowda, Mahendra, Sukhorukov, Alexey, Pandey, Vijay, Lobie, Peter E., Basappa, Basappa, Ahn, Kwang Seok

“…•To overcome drug-resistant breast cancer, it is essential to develop compounds that induce apoptosis and paraptosis.•BSO-07 triggered G1 phase arrest, cleaved…”
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Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells by Suresha N. Deveshegowda, Ji-Rui Yang, Zhang Xi, Omantheswara Nagaraja, Kashifa Fazl-Ur-Rahman, Bhanuprakash C. Narasimhachar, Gautam Sethi, Ganga Periyasamy, Mahendra Madegowda, Shobith Rangappa, Vijay Pandey, Peter E. Lobie, Basappa Basappa

“…Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a multicomponent Biginelli reaction. The reaction was catalyzed by the polarized surface…”
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Methyl-Thiol-Bridged Oxadiazole and Triazole Heterocycles as Inhibitors of NF-κB in Chronic Myelogenous Leukemia Cells by Basappa, Basappa, Jung, Young Yun, Ravish, Akshay, Xi, Zhang, Swamynayaka, Ananda, Madegowda, Mahendra, Pandey, Vijay, Lobie, Peter E, Sethi, Gautam, Ahn, Kwang Seok

“…Nuclear factor kappa beta (NF-κB) is a transcriptional factor that plays a crucial role in regulating cancer cell proliferation. Therefore, the inhibition of…”
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Crystal structure, DFT calculation, Hirshfeld surface analysis and energy framework study of 6-bromo-2-(4-bromo-phen-yl)imidazo[1,2- a ]pyridine by Khamees, Hussien Ahmed, Chaluvaiah, Kumara, El-Khatatneh, Nasseem Ahmed, Swamynayaka, Ananda, Chong, Kwong Huey, Dasappa, Jagadeesh Prasad, Madegowda, Mahendra

“…The title imidazo[1,2- ] pyridine derivative, C H Br N , was synthesized a single-step reaction method. The title mol-ecule is planar, showing a dihedral angle…”
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De Novo Design of Imidazopyridine-Tethered Pyrazolines That Target Phosphorylation of STAT3 in Human Breast Cancer Cells by Ravish, Akshay, Shivakumar, Rashmi, Xi, Zhang, Yang, Min Hee, Yang, Ji-Rui, Swamynayaka, Ananda, Nagaraja, Omantheswara, Madegowda, Mahendra, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Pandey, Vijay, Sethi, Gautam, Ahn, Kwang Seok, Lobie, Peter E, Basappa, Basappa

“…In breast cancer (BC), STAT3 is hyperactivated. This study explored the design of imidazopyridine-tethered pyrazolines as a de novo drug strategy for…”
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Nano-Zirconium Dioxide Catalyzed Multicomponent Synthesis of Bioactive Pyranopyrazoles That Target Cyclin Dependent Kinase 1 in Human Breast Cancer Cells by Basappa, Basappa, Poonacha, Lisha K, Xi, Zhang, Vishwanath, Divakar, Yang, Ji-Rui, Nagaraja, Omantheswara, Swamynayaka, Ananda, Madegowda, Mahendra, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Gurudatt, Doddahosuru Mahadevappa, Pandey, Vijay, Shivananju, Nanjundaswamy, Ahn, Kwang Seok, Sethi, Gautam, Lobie, Peter E, Shubha, Priya Babu

“…Small molecules are being used to inhibit cyclin dependent kinase (CDK) enzymes in cancer treatment. There is evidence that CDK is a drug-target for cancer…”
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Structural genomics of protein phosphatases by Almo, Steven C, Bonanno, Jeffrey B, Sauder, J Michael, Emtage, Spencer, Dilorenzo, Teresa P, Malashkevich, Vladimir, Wasserman, Steven R, Swaminathan, S, Eswaramoorthy, Subramaniam, Agarwal, Rakhi, Kumaran, Desigan, Madegowda, Mahendra, Ragumani, Sugadev, Patskovsky, Yury, Alvarado, Johnjeff, Ramagopal, Udupi A, Faber-Barata, Joana, Chance, Mark R, Sali, Andrej, Fiser, Andras, Zhang, Zhong-yin, Lawrence, David S, Burley, Stephen K

“…The New York SGX Research Center for Structural Genomics (NYSGXRC) of the NIGMS Protein Structure Initiative (PSI) has applied its high-throughput X-ray…”
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ArsP: a methylarsenite efflux permease by Chen, Jian, Madegowda, Mahendra, Bhattacharjee, Hiranmoy, Rosen, Barry P.

“…Summary Trivalent organoarsenic compounds are far more toxic than either pentavalent organoarsenicals or inorganic arsenite. Many microbes methylate inorganic…”
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Synthesis, crystal structure, spectroscopic characterization, docking simulation and density functional studies of 1-(3,4-dimethoxyphenyl) -3-(4-flurophenyl)-propan-1-one by Khamees, Hussien Ahmed, Jyothi, Mahima, Khanum, Shaukath Ara, Madegowda, Mahendra

“…The compound 1-(3,4-dimethoxyphenyl)-3-(4-flurophenyl)-propan-1-one (DFPO) was synthesized by Claisen-Schmidt condensation reaction and the single crystals…”
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A novel Schiff base derivative as a fluorescent probe for selective detection of Cu2+ ions in buffered solution at pH 7.5: Experimental and quantum chemical calculations by Revanna, Bhavya Nelligere, Madegowda, Mahendra, Neelufar, Rangaswamy, Javarappa, Naik, Nagaraja

“…•A new Schiff base fluorescent turn-off sensor NF1 has been synthesized and developed.•Global reactivity descriptors and excited state properties were…”
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Synthesis of N1 and N2 coumarin substituted 1,2,3-triazole isomers via click chemistry approach by Shamala, Devadas, Shivashankar, Kalegowda, Chandra, Mahendra, Madegowda

“…The synthesis of N 1 and N 2 coumarin substituted 1,2,3-triazole isomers from terminal alkynes, sodium azide, and 4-bromomethylcoumarins in the presence of…”
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Synthesis of N 1 and N 2 coumarin substituted 1,2,3-triazole isomers via click chemistry approach by Shamala, Devadas, Shivashankar, Kalegowda, Chandra, Mahendra, Madegowda

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Third-order nonlinear response of a novel organic acetohydrazide derivative: Experimental and theoretical approach by Swamynayaka, Ananda, Venkatesha, Keerthikumara, Harish, Keshav Kumar, Revanna, Bhavya Nelligere, Venkatesh, Chethan, Madegowda, Mahendra, Hegde, Tejaswi Ashok

“…A novel nonlinear optical (NLO) organic material of N'-[(E)-(5-bromofuran-2-yl)methylidene]-2-(6-chloropyridin-3-yl)acetohydrazide (BCA) was synthesized by…”
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