Search Results - "Madduri, Srinivas"

A comprehensive review of silk-fibroin hydrogels for cell and drug delivery applications in tissue engineering and regenerative medicine by Madappura, Alakananda Parassini, Madduri, Srinivas

“…Hydrogel scaffolds hold great promise for developing novel treatment strategies in the field of regenerative medicine. Within this context, silk fibroin (SF)…”
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Schwann cell delivery of neurotrophic factors for peripheral nerve regeneration by Madduri, Srinivas, Gander, Bruno

“…Current treatments of injured peripheral nerves often fail to mediate satisfactory functional recovery. For axonal regeneration, neurotrophic factors (NTFs)…”
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Synergistic effect of GDNF and NGF on axonal branching and elongation in vitro by Madduri, Srinivas, Papaloïzos, Michaël, Gander, Bruno

“…There is a clinical need to enhance functional recovery of injured peripheral nerves. Local administration of neurotrophic factors (NTFs) after surgical repair…”
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Therapeutic Potential and Challenges of Mesenchymal Stem Cell-Derived Exosomes for Peripheral Nerve Regeneration: A Systematic Review by Dogny, Clelia, André-Lévigne, Dominik, Kalbermatten, Daniel F, Madduri, Srinivas

“…Gap injuries to the peripheral nervous system result in pain and loss of function, without any particularly effective therapeutic options. Within this context,…”
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A bilayered hybrid microfibrous PLGA–Acellular matrix scaffold for hollow organ tissue engineering by Horst, Maya, Madduri, Srinivas, Milleret, Vincent, Sulser, Tullio, Gobet, Rita, Eberli, Daniel

“…Abstract Various synthetic and natural biomaterials have been used for regeneration of tissues and hollow organs. However, clinical outcome of reconstructive…”
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Role of Oxygen and Its Radicals in Peripheral Nerve Regeneration: From Hypoxia to Physoxia to Hyperoxia by André-Lévigne, Dominik, Pignel, Rodrigue, Boet, Sylvain, Jaquet, Vincent, Kalbermatten, Daniel F, Madduri, Srinivas

“…Oxygen is compulsory for mitochondrial function and energy supply, but it has numerous more nuanced roles. The different roles of oxygen in peripheral nerve…”
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3D stem-like spheroids-on-a-chip for personalized combinatorial drug testing in oral cancer by Mehta, Viraj, Vilikkathala Sudhakaran, Sukanya, Nellore, Vijaykumar, Madduri, Srinivas, Rath, Subha Narayan

“…Functional drug testing (FDT) with patient-derived tumor cells in microfluidic devices is gaining popularity. However, the majority of previously reported…”
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The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Preclinical Evidence by Oranges, Carlo M., Striebel, Julia, Tremp, Mathias, Madduri, Srinivas, Kalbermatten, Daniel F., Harder, Yves, Schaefer, Dirk J.

“…Several methods to prepare the recipient site in fat grafting have been proposed in recent decades. However, to date, these procedures have never been reviewed…”
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Emerging Strategies for the Biofabrication of Multilayer Composite Amniotic Membranes for Biomedical Applications by Fenelon, Mathilde, Galvez, Paul, Kalbermatten, Daniel, Scolozzi, Paolo, Madduri, Srinivas

“…The amniotic membrane (AM) is the innermost part of the fetal placenta, which surrounds and protects the fetus. Due to its structural components (stem cells,…”
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Schwann Cell-Like Cells: Origin and Usability for Repair and Regeneration of the Peripheral and Central Nervous System by Hopf, Alois, Schaefer, Dirk J, Kalbermatten, Daniel F, Guzman, Raphael, Madduri, Srinivas

“…Functional recovery after neurotmesis, a complete transection of the nerve fiber, is often poor and requires a surgical procedure. Especially for longer gaps…”
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Mesenchymal Stem Cells in Nerve Tissue Engineering: Bridging Nerve Gap Injuries in Large Animals by Lischer, Mirko, di Summa, Pietro G, Petrou, Ilias G, Schaefer, Dirk J, Guzman, Raphael, Kalbermatten, Daniel F, Madduri, Srinivas

“…Cell-therapy-based nerve repair strategies hold great promise. In the field, there is an extensive amount of evidence for better regenerative outcomes when…”
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Effect of controlled co-delivery of synergistic neurotrophic factors on early nerve regeneration in rats by Madduri, Srinivas, di Summa, Pietro, Papaloïzos, Michaël, Kalbermatten, Daniel, Gander, Bruno

“…Abstract Present interventions to repair severed peripheral nerves provide slow and poor early axonal regeneration, which may cause unsatisfactory functional…”
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Editorial: Emerging Therapeutic Approaches for Repair and Regeneration of Injuries in the Peripheral Nervous System by Salgado, Antonio, Navarro, Xavier, Madduri, Srinivas

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Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells by di Summa, Pietro, Madduri, Srinivas

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Adipose Derived Stem Cells Reduce Fibrosis and Promote Nerve Regeneration in Rats by Di Summa, Pietro G., Schiraldi, Luigi, Cherubino, Mario, Oranges, Carlo M., Kalbermatten, Daniel F., Raffoul, Wassim, Madduri, Srinivas

“…ABSTRACT Peripheral nerve regeneration is critical and challenging in the adult humans. High level of collagen infiltration (i.e., scar tissue), in the niche…”
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Optimized Decellularization Protocol for Large Peripheral Nerve Segments: Towards Personalized Nerve Bioengineering by Hopf, Alois, Al-Bayati, Lina, Schaefer, Dirk J, Kalbermatten, Daniel F, Guzman, Raphael, Madduri, Srinivas

“…Nerve injuries remain clinically challenging, and allografts showed great promise. Decellularized nerve allografts possess excellent biocompatibility and…”
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The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation by Petrou, Ilias G, Nikou, Sofia, Madduri, Srinivas, Nifora, Martha, Bravou, Vasiliki, Kalbermatten, Daniel F

“…Keloids and hypertrophic scars are characterized by abnormal fibroblast activation and proliferation. While their molecular pathogenesis remains unclear,…”
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Diagnostic and Therapeutic Roles of the "Omics" in Hypoxic-Ischemic Encephalopathy in Neonates by Rasineni, Girish Kumar, Panigrahy, Nalinikanta, Rath, Subha Narayan, Chinnaboina, Madhurarekha, Konanki, Ramesh, Chirla, Dinesh Kumar, Madduri, Srinivas

“…Perinatal asphyxia and neonatal encephalopathy remain major causes of neonatal mortality, despite the improved availability of diagnostic and therapeutic…”
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Ex-Vivo Stimulation of Adipose Stem Cells by Growth Factors and Fibrin-Hydrogel Assisted Delivery Strategies for Treating Nerve Gap-Injuries by Prautsch, Katharina M, Degrugillier, Lucas, Schaefer, Dirk J, Guzman, Raphael, Kalbermatten, Daniel F, Madduri, Srinivas

“…Peripheral nerve injuries often result in lifelong disabilities despite advanced surgical interventions, indicating the urgent clinical need for effective…”
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Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives by Hostettler, Isabel C., Jayashankar, Narayan, Bikis, Christos, Wanderer, Stefan, Nevzati, Edin, Karuppiah, Ravindran, Waran, Vicknes, Kalbermatten, Daniel, Mariani, Luigi, Marbacher, Serge, Guzman, Raphael, Madduri, Srinivas, Roethlisberger, Michel

“…Background and purpose: Tumorous lesions developing in the cerebellopontine angle (CPA) get into close contact with the 1st (cisternal) and 2nd (meatal)…”
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