Search Results - "Maddock, H."

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    Facilitating the Ferration of Aromatic Substrates through Intramolecular Sodium Mediation by Maddock, Lewis C. H., Mu, Manting, Kennedy, Alan R., García‐Melchor, Max, Hevia, Eva

    Published in Angewandte Chemie International Edition (05-07-2021)
    “…Exploiting cooperative effects between Na and FeII centres present in tris(amide) ferrate complexes has led to the chemoselective ferration of…”
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    Lateral Metallation and Redistribution Reactions of Sodium Ferrates Containing Bulky 2,6‐Diisopropyl‐N‐(trimethylsilyl)anilide Ligands by Maddock, Lewis C. H., Morton, Rebekka, Kennedy, Alan R., Hevia, Eva

    Published in Chemistry : a European journal (02-11-2021)
    “…Alkali‐metal ferrates containing amide groups have emerged as regioselective bases capable of promoting Fe−H exchanges of aromatic substrates. Advancing this…”
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    Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore by Gharanei, M., Hussain, A., Janneh, O., Maddock, H.L.

    Published in Toxicology and applied pharmacology (15-04-2013)
    “…Chemotherapeutic agents such as doxorubicin are known to cause or exacerbate cardiovascular cell death when an underlying heart condition is present. However,…”
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  4. 4

    Lithium-mediated Ferration of Fluoroarenes by Maddock, Lewis C. H., Kennedy, Alan, Hevia, Eva

    Published in Chimia (01-11-2020)
    “…While fluoroaryl fragments are ubiquitous in many pharmaceuticals, the deprotonation of fluoroarenes using organolithium bases constitutes an important…”
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    Accessing Sodium Ferrate Complexes Containing Neutral and Anionic N‑Heterocyclic Carbene Ligands: Structural, Synthetic, and Magnetic Insights by Maddock, Lewis C. H, Cadenbach, Thomas, Kennedy, Alan R, Borilovic, Ivana, Aromí, Guillem, Hevia, Eva

    Published in Inorganic chemistry (21-09-2015)
    “…This study reports the synthesis and single-crystal X-ray crystallographic, NMR spectroscopic, and magnetic characterization of a series of sodium ferrates…”
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    Understanding the future research needs in Postural Orthostatic Tachycardia Syndrome (POTS): Evidence mapping the POTS adult literature by Eftekhari, H., Maddock, H., Pearce, G., Raza, S., Kavi, L., Lim, P.B., Osman, F., Hayat, S.A.

    Published in Autonomic neuroscience (01-07-2021)
    “…POTS is under diagnosed with an estimated prevalence of 0.2%. North American and Australian researchers, as well as patient groups have called for more…”
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  7. 7

    The role of nitric oxide in A3 adenosine receptor-mediated cardioprotection by Hussain, A, Karjian, P, Maddock, H

    Published in Autonomic & autacoid pharmacology (01-07-2009)
    “…1 Limiting the impact of ischemia reperfusion-related cell death is of vital importance given the enormous figures of heart related mortality in the world. 2…”
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    Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide by MOCANU, Mihaela M, MADDOCK, Helen L, BAXTER, Gary F, LAWRENCE, Christina L, STANDEN, Nicholas B, YELLON, Derek M

    Published in Circulation (New York, N.Y.) (26-06-2001)
    “…The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial K(ATP)…”
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    Conflicting human interests over the re-introduction of endangered wild dogs in South Africa by Gusset, Markus, Maddock, Anthony H, Gunther, Glenn J, Szykman, Micaela, Slotow, Rob, Walters, Michele, Somers, Michael J

    Published in Biodiversity and conservation (2008)
    “…In South Africa, a plan was launched to manage separate sub-populations of endangered African wild dogs (Lycaon pictus) in several small, geographically…”
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    Ethanol- and/or Taurine-Induced Oxidative Stress in Chick Embryos by Michels, Kathryn G., Mugge, Luke A., Nass, Catherine M., Yearsley, Sarah M., Miller, Robert R., Berning, Emily J., Maddock, Benjamin H., Lanctot, Alison, Gushrowski, Courtney M., Bernhardson, Noah, Coleman, Kelly, Farhat, Dina A.

    Published in Journal of Amino Acids (01-01-2013)
    “…Because taurine alleviates ethanol- (EtOH-) induced lipid peroxidation and liver damage in rats, we asked whether exogenous taurine could alleviate…”
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    Structural and Synthetic Insights into Sodium‐Mediated‐Ferration of Fluoroarenes by Maddock, Lewis C. H., Kennedy, Alan R., Hevia, Eva

    Published in Helvetica chimica acta (01-12-2021)
    “…Exploiting chemical cooperation between Na and Fe(II) within the bimetallic base [dioxane ⋅ NaFe(HMDS)3] (I), (dioxane=1,4‐dioxane, HMDS=N(SiMe3)2) the…”
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    Boosting Conjugate Addition to Nitroolefins Using Lithium Tetraorganozincates: Synthetic Strategies and Structural Insights by Dell'Aera, Marzia, Perna, Filippo Maria, Vitale, Paola, Altomare, Angela, Palmieri, Alessandro, Maddock, Lewis C. H., Bole, Leonie J., Kennedy, Alan R., Hevia, Eva, Capriati, Vito

    Published in Chemistry : a European journal (17-07-2020)
    “…We report the first transition metal catalyst‐ and ligand‐free conjugate addition of lithium tetraorganozincates (R4ZnLi2) to nitroolefins. Displaying enhanced…”
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    Dual behavior of N-acetylcysteine during ethanol-induced oxidative stress in embryonic chick brains by Bauer, Alison K., Fitzgerald, Mary, Ladzinski, Adam T., Lenhart Sherman, Sydney, Maddock, Benjamin H., Norr, Zoe M., Miller, Robert R.

    Published in Nutritional neuroscience (14-09-2017)
    “…Objectives: Ethanol (EtOH) causes oxidative stress in embryos. Because N-acetylcysteine (NAC) failures and successes in ameliorating EtOH-induced oxidative…”
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  19. 19

    Utilising Sodium‐Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C−H and C−F Bond Activations by Maddock, Lewis C. H., Nixon, Tracy, Kennedy, Alan R., Probert, Michael R., Clegg, William, Hevia, Eva

    Published in Angewandte Chemie International Edition (02-01-2018)
    “…Pairing iron bis(amide) Fe(HMDS)2 with Na(HMDS) to form new sodium ferrate base [(dioxane)0.5⋅NaFe(HMDS)3] (1) enables regioselective mono and di‐ferration…”
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    Unlocking the Metalation Applications of TMP‐powered Fe and Co(II) bis(amides): Synthesis, Structure and Mechanistic Insights by Logallo, Alessandra, Maddock, Lewis C. H., Mu, Manting, Gravogl, Lisa, Jin, Na, Peñas‐Defrutos, Marconi N., Meyer, Karsten, García‐Melchor, Max, Hevia, Eva

    Published in Angewandte Chemie International Edition (10-06-2024)
    “…Typified by LiTMP and TMPMgCl.LiCl, (TMP=2,2,6,6‐tetramethylpiperidide), s‐block metal amides have found widespread applications in arene deprotonative…”
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