Search Results - "Maddock, H"

Facilitating the Ferration of Aromatic Substrates through Intramolecular Sodium Mediation by Maddock, Lewis C. H., Mu, Manting, Kennedy, Alan R., García‐Melchor, Max, Hevia, Eva

“…Exploiting cooperative effects between Na and FeII centres present in tris(amide) ferrate complexes has led to the chemoselective ferration of…”
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Lateral Metallation and Redistribution Reactions of Sodium Ferrates Containing Bulky 2,6‐Diisopropyl‐N‐(trimethylsilyl)anilide Ligands by Maddock, Lewis C. H., Morton, Rebekka, Kennedy, Alan R., Hevia, Eva

“…Alkali‐metal ferrates containing amide groups have emerged as regioselective bases capable of promoting Fe−H exchanges of aromatic substrates. Advancing this…”
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Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore by Gharanei, M., Hussain, A., Janneh, O., Maddock, H.L.

“…Chemotherapeutic agents such as doxorubicin are known to cause or exacerbate cardiovascular cell death when an underlying heart condition is present. However,…”
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Lithium-mediated Ferration of Fluoroarenes by Maddock, Lewis C. H., Kennedy, Alan, Hevia, Eva

“…While fluoroaryl fragments are ubiquitous in many pharmaceuticals, the deprotonation of fluoroarenes using organolithium bases constitutes an important…”
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Accessing Sodium Ferrate Complexes Containing Neutral and Anionic N‑Heterocyclic Carbene Ligands: Structural, Synthetic, and Magnetic Insights by Maddock, Lewis C. H, Cadenbach, Thomas, Kennedy, Alan R, Borilovic, Ivana, Aromí, Guillem, Hevia, Eva

“…This study reports the synthesis and single-crystal X-ray crystallographic, NMR spectroscopic, and magnetic characterization of a series of sodium ferrates…”
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Understanding the future research needs in Postural Orthostatic Tachycardia Syndrome (POTS): Evidence mapping the POTS adult literature by Eftekhari, H., Maddock, H., Pearce, G., Raza, S., Kavi, L., Lim, P.B., Osman, F., Hayat, S.A.

“…POTS is under diagnosed with an estimated prevalence of 0.2%. North American and Australian researchers, as well as patient groups have called for more…”
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The role of nitric oxide in A3 adenosine receptor-mediated cardioprotection by Hussain, A, Karjian, P, Maddock, H

“…1 Limiting the impact of ischemia reperfusion-related cell death is of vital importance given the enormous figures of heart related mortality in the world. 2…”
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Investigating the Cardioprotective role of Metformin during Sunitinib-induced Cardiotoxicity by qRT-PCR profiling of microRNAs associated with myocardial injury by Sandhu, H., Maddock, H.

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Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide by MOCANU, Mihaela M, MADDOCK, Helen L, BAXTER, Gary F, LAWRENCE, Christina L, STANDEN, Nicholas B, YELLON, Derek M

“…The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial K(ATP)…”
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Conflicting human interests over the re-introduction of endangered wild dogs in South Africa by Gusset, Markus, Maddock, Anthony H, Gunther, Glenn J, Szykman, Micaela, Slotow, Rob, Walters, Michele, Somers, Michael J

“…In South Africa, a plan was launched to manage separate sub-populations of endangered African wild dogs (Lycaon pictus) in several small, geographically…”
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Ethanol- and/or Taurine-Induced Oxidative Stress in Chick Embryos by Michels, Kathryn G., Mugge, Luke A., Nass, Catherine M., Yearsley, Sarah M., Miller, Robert R., Berning, Emily J., Maddock, Benjamin H., Lanctot, Alison, Gushrowski, Courtney M., Bernhardson, Noah, Coleman, Kelly, Farhat, Dina A.

“…Because taurine alleviates ethanol- (EtOH-) induced lipid peroxidation and liver damage in rats, we asked whether exogenous taurine could alleviate…”
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An unusual case of hysterical postoperative coma by Maddock, H., Carley, S., McCluskey, A.

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Efforts going to the dogs? Evaluating attempts to re-introduce endangered wild dogs in South Africa by Gusset, Markus, Ryan, Sadie J, Hofmeyr, Markus, Van Dyk, Gus, Davies-Mostert, Harriet T, Graf, Jan A, Owen, Cailey, Szykman, Micaela, Macdonald, David W, Monfort, Steven L, Wildt, David E, Maddock, Anthony H, Mills, M. Gus L, Slotow, Rob, Somers, Michael J

“…1. We evaluated one of the most extensive efforts to date to re-introduce an endangered species: attempts to establish an actively managed meta-population of…”
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Some data on the feeding habits of the banded mongoose in a coastal area (South Africa) by Maddock, Ant H., Do Linh San, Emmanuel, Perrin, Mike R.

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Structural and Synthetic Insights into Sodium‐Mediated‐Ferration of Fluoroarenes by Maddock, Lewis C. H., Kennedy, Alan R., Hevia, Eva

“…Exploiting chemical cooperation between Na and Fe(II) within the bimetallic base [dioxane ⋅ NaFe(HMDS)3] (I), (dioxane=1,4‐dioxane, HMDS=N(SiMe3)2) the…”
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P1747A1 Adenosine receptor activation can protect the myocardium from ischaemia reperfusion injury post reperfusion by Bhandal, J., Renshaw, D., Buckley, J., Maddock, H., Hussain, A.

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Boosting Conjugate Addition to Nitroolefins Using Lithium Tetraorganozincates: Synthetic Strategies and Structural Insights by Dell'Aera, Marzia, Perna, Filippo Maria, Vitale, Paola, Altomare, Angela, Palmieri, Alessandro, Maddock, Lewis C. H., Bole, Leonie J., Kennedy, Alan R., Hevia, Eva, Capriati, Vito

“…We report the first transition metal catalyst‐ and ligand‐free conjugate addition of lithium tetraorganozincates (R4ZnLi2) to nitroolefins. Displaying enhanced…”
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Dual behavior of N-acetylcysteine during ethanol-induced oxidative stress in embryonic chick brains by Bauer, Alison K., Fitzgerald, Mary, Ladzinski, Adam T., Lenhart Sherman, Sydney, Maddock, Benjamin H., Norr, Zoe M., Miller, Robert R.

“…Objectives: Ethanol (EtOH) causes oxidative stress in embryos. Because N-acetylcysteine (NAC) failures and successes in ameliorating EtOH-induced oxidative…”
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Utilising Sodium‐Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C−H and C−F Bond Activations by Maddock, Lewis C. H., Nixon, Tracy, Kennedy, Alan R., Probert, Michael R., Clegg, William, Hevia, Eva

“…Pairing iron bis(amide) Fe(HMDS)2 with Na(HMDS) to form new sodium ferrate base [(dioxane)0.5⋅NaFe(HMDS)3] (1) enables regioselective mono and di‐ferration…”
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Unlocking the Metalation Applications of TMP‐powered Fe and Co(II) bis(amides): Synthesis, Structure and Mechanistic Insights by Logallo, Alessandra, Maddock, Lewis C. H., Mu, Manting, Gravogl, Lisa, Jin, Na, Peñas‐Defrutos, Marconi N., Meyer, Karsten, García‐Melchor, Max, Hevia, Eva

“…Typified by LiTMP and TMPMgCl.LiCl, (TMP=2,2,6,6‐tetramethylpiperidide), s‐block metal amides have found widespread applications in arene deprotonative…”
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