Search Results - "Maddison, Ben C."

REVIEW: The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology by Rees, Helen C, Maddison, Ben C, Middleditch, David J, Patmore, James R.M, Gough, Kevin C, Crispo, Erika

“…Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations,…”
Get full text

Recombinant ovine prion protein can be mutated at position 136 to improve its efficacy as an inhibitor of prion propagation by Kopycka, Katarzyna, Maddison, Ben C., Gough, Kevin C.

“…Prion diseases are progressive neurodegenerative disorders with no effective therapeutics. The central event leading to the pathology in the diseases is the…”
Get full text

A Trematode Parasite Derived Growth Factor Binds and Exerts Influences on Host Immune Functions via Host Cytokine Receptor Complexes by Sulaiman, Azad A, Zolnierczyk, Katarzyna, Japa, Ornampai, Owen, Jonathan P, Maddison, Ben C, Emes, Richard D, Hodgkinson, Jane E, Gough, Kevin C, Flynn, Robin J

“…The trematode Fasciola hepatica is responsible for chronic zoonotic infection globally. Despite causing a potent T-helper 2 response, it is believed that…”
Get full text

Quantitative PCR (qPCR) assay for the specific detection of the Chinese mystery snail (Cipangopaludina chinensis) in the UK by Rees, Helen C., Measures, Gavin H., Kane, Steven D., Maddison, Ben C.

“…Cipangopaludina chinensis Gray 1833 is an East Asian freshwater snail and invasive species in many parts of the world (Global Invasive Species Database, 2022)…”
Get full text

A qPCR assay for the rapid and specific detection of Shining ram’s-horn snail (Segmentina nitida) eDNA from Stodmarsh National Nature Reserve, UK by Rees, Helen C, Cousins, Mags E, Baker, Claire A, Maddison, Ben C

“…Segmentina nitida Müller 1774 is a freshwater snail which was formerly widespread throughout England and south Wales. Since the 1840s it has seen a rapid…”
Get full text

The application of eDNA for monitoring of the Great Crested Newt in the UK by Rees, Helen C., Bishop, Keith, Middleditch, David J., Patmore, James R. M., Maddison, Ben C., Gough, Kevin C.

“…Current ecological surveys for great crested newts are time‐consuming and expensive and can only be carried out within a short survey window. Additional survey…”
Get full text

Prion transmission: Prion excretion and occurrence in the environment by Gough, Kevin C., Maddison, Ben C.

“…Prion diseases range from being highly infectious, for example scrapie and CWD which show facile transmission between susceptible individuals, to showing…”
Get full text

Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents by Marín-Moreno, Alba, Benestad, Sylvie L, Barrio, Tomas, Pirisinu, Laura, Espinosa, Juan Carlos, Tran, Linh, Huor, Alvina, Di Bari, Michele Angelo, Eraña, Hasier, Maddison, Ben C, D'Agostino, Claudia, Fernández-Borges, Natalia, Canoyra, Sara, Jerez-Garrido, Nuria, Castilla, Joaquín, Spiropoulos, John, Bishop, Keith, Gough, Kevin C, Nonno, Romolo, Våge, Jorn, Andréoletti, Olivier, Torres, Juan María

“…The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem…”
Get full text

BSE can propagate in sheep co-infected or pre-infected with scrapie by Chong, Angela, Foster, James D., Goldmann, Wilfred, Gonzalez, Lorenzo, Jeffrey, Martin, O’Connor, Matthew J., Bishop, Keith, Maddison, Ben C., Houston, E. Fiona, Gough, Kevin C., Hunter, Nora

“…To understand the possible role of mixed-prion infections in disease presentation, the current study reports the co-infection of sheep with bovine spongiform…”
Get full text

Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals by Rees, Helen C., Gough, Kevin C., Middleditch, David J., Patmore, James R. M., Maddison, Ben C.

“…1. In Rees et al. (2014b), we reviewed the current status of environmental DNA (eDNA) to monitor aquatic populations. Our aim was to focus on discussion of…”
Get full text

The detection of great crested newts year round via environmental DNA analysis by Rees, Helen C, Baker, Claire A, Gardner, David S, Maddison, Ben C, Gough, Kevin C

“…Analysis of environmental DNA (eDNA) is a method that has been used for the detection of various species within water bodies. The great crested newt (Triturus…”
Get full text

Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets by Spiliotopoulos, Anastasios, Owen, Jonathan.P., Maddison, Ben.C., Dreveny, Ingrid, Rees, Helen.C., Gough, Kevin.C.

“…Recently the analytical power of the latest high throughput next generation DNA sequencing platforms has been used to analyse phage that have been selected…”
Get full text

Environmental Sources of Scrapie Prions by MADDISON, Ben C, BAKER, Claire A, TERRY, Linda A, BELLWORTHY, Susan J, THORNE, Leigh, REES, Helen C, GOUGH, Kevin C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Prions Are Secreted into the Oral Cavity in Sheep with Preclinical Scrapie by Maddison, Ben C., Rees, Helen C., Baker, Claire A., Taema, Maged, Bellworthy, Susan J., Thorne, Leigh, Terry, Linda A., Gough, Kevin C.

“…A major concern in prion disease transmission is the spread of the disease agent by means of secretions and excretions. We analyzed buccal swab samples…”
Get full text

Oral Secretion of Infectious Scrapie Prions Occurs in Preclinical Sheep with a Range of PRNP Genotypes by Gough, Kevin C, Baker, Claire A, Rees, Helen C, Terry, Linda A, Spiropoulos, John, Thorne, Leigh, Maddison, Ben C

“…Preclinical sheep with the highly scrapie-susceptible VRQ/VRQ PRNP genotype secrete prions from the oral cavity. In order to further understand the…”
Get full text

Detection of prions in the faeces of sheep naturally infected with classical scrapie by Terry, Linda A, Howells, Laurence, Bishop, Keith, Baker, Claire A, Everest, Sally, Thorne, Leigh, Maddison, Ben C, Gough, Kevin C

“…Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence…”
Get full text

The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology by Rees, Helen C., Maddison, Ben C., Middleditch, David J., Patmore, James R.M., Gough, Kevin C.

“…1. Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations,…”
Get full text

Isolation of phage-antibodies against Eimeria species that infect chickens by Angani, Mary T., Owen, Jonathan P., Maddison, Ben C., Gough, Kevin C.

“…Eimeria is one of the most economically important pathogens in poultry production. Diagnosis of infection has the potential to inform treatment and prevention…”
Get full text

Methods for Differentiating Prion Types in Food-Producing Animals by Gough, Kevin C, Rees, Helen C, Ives, Sarah E, Maddison, Ben C

“…Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by…”
Get full text

Advances in the Production and Batch Reformatting of Phage Antibody Libraries by Reader, Rose H., Workman, Robert G., Maddison, Ben C., Gough, Kevin C.

“…Phage display antibody libraries have proven an invaluable resource for the isolation of diagnostic and potentially therapeutic antibodies, the latter usually…”
Get full text