Search Results - "Madden, Pamela A."

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits by Yang, Jian, Ferreira, Teresa, Morris, Andrew P, Medland, Sarah E, Madden, Pamela A F, Heath, Andrew C, Martin, Nicholas G, Montgomery, Grant W, Weedon, Michael N, Loos, Ruth J, Frayling, Timothy M, McCarthy, Mark I, Hirschhorn, Joel N, Goddard, Michael E, Visscher, Peter M

“…Peter Visscher and colleagues report a new method for approximate conditional and joint association analysis that makes use of summary statistics from…”
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Common SNPs explain a large proportion of the heritability for human height by Heath, Andrew C, Benyamin, Beben, Nyholt, Dale R, Goddard, Michael E, Gordon, Scott, Martin, Nicholas G, Henders, Anjali K, Madden, Pamela A, Visscher, Peter M, McEvoy, Brian P, Yang, Jian, Montgomery, Grant W

“…Peter Visscher and colleagues report an analysis of the heritability explained by common variants identified through genome-wide association studies. They find…”
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Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent by Buchwald, Jadwiga, Chenoweth, Meghan J., Palviainen, Teemu, Zhu, Gu, Benner, Christian, Gordon, Scott, Korhonen, Tellervo, Ripatti, Samuli, Madden, Pamela A. F., Lehtimäki, Terho, Raitakari, Olli T., Salomaa, Veikko, Rose, Richard J., George, Tony P., Lerman, Caryn, Pirinen, Matti, Martin, Nicholas G., Kaprio, Jaakko, Loukola, Anu, Tyndale, Rachel F.

“…Smoking behaviors, including amount smoked, smoking cessation, and tobacco-related diseases, are altered by the rate of nicotine clearance. Nicotine clearance…”
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Association between nicotine withdrawal and reward responsiveness in humans and rats by Pergadia, Michele L, Der-Avakian, Andre, D'Souza, Manoranjan S, Madden, Pamela A F, Heath, Andrew C, Shiffman, Saul, Markou, Athina, Pizzagalli, Diego A

“…Reward-related disturbances after withdrawal from nicotine are hypothesized to contribute to relapse to tobacco smoking but mechanisms underlying and linking…”
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Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs by Saccone, Scott F., Hinrichs, Anthony L., Saccone, Nancy L., Chase, Gary A., Konvicka, Karel, Madden, Pamela A.F., Breslau, Naomi, Johnson, Eric O., Hatsukami, Dorothy, Pomerleau, Ovide, Swan, Gary E., Goate, Alison M., Rutter, Joni, Bertelsen, Sarah, Fox, Louis, Fugman, Douglas, Martin, Nicholas G., Montgomery, Grant W., Wang, Jen C., Ballinger, Dennis G., Rice, John P., Bierut, Laura Jean

“…Nicotine dependence is one of the world's leading causes of preventable death. To discover genetic variants that influence risk for nicotine dependence, we…”
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Overlapping genetic and environmental influences on nonsuicidal self-injury and suicidal ideation: different outcomes, same etiology? by Maciejewski, Dominique F, Creemers, Hanneke E, Lynskey, Michael T, Madden, Pamela A F, Heath, Andrew C, Statham, Dixie J, Martin, Nicholas G, Verweij, Karin J H

“…Nonsuicidal self-injury (NSSI) and suicidal self-injury are very harmful behaviors and are associated with several psychiatric disorders. In the recently…”
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Novel genes identified in a high-density genome wide association study for nicotine dependence by Bierut, Laura Jean, Madden, Pamela A.F., Breslau, Naomi, Johnson, Eric O., Hatsukami, Dorothy, Pomerleau, Ovide F., Swan, Gary E., Rutter, Joni, Bertelsen, Sarah, Fox, Louis, Fugman, Douglas, Goate, Alison M., Hinrichs, Anthony L., Konvicka, Karel, Martin, Nicholas G., Montgomery, Grant W., Saccone, Nancy L., Saccone, Scott F., Wang, Jen C., Chase, Gary A., Rice, John P., Ballinger, Dennis G.

“…Tobacco use is a leading contributor to disability and death worldwide, and genetic factors contribute in part to the development of nicotine dependence. To…”
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Genetic aetiology of self-harm ideation and behaviour by Campos, Adrian I., Verweij, Karin J. H., Statham, Dixie J., Madden, Pamela A. F., Maciejewski, Dominique F., Davis, Katrina A. S., John, Ann, Hotopf, Matthew, Heath, Andrew C., Martin, Nicholas G., Rentería, Miguel E.

“…Family studies have identified a heritable component to self-harm that is partially independent from comorbid psychiatric disorders. However, the genetic…”
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Variants in Nicotinic Receptors and Risk for Nicotine Dependence by Bierut, Laura Jean, Stitzel, Jerry A., Wang, Jen C., Hinrichs, Anthony L., Grucza, Richard A., Xuei, Xiaoling, Saccone, Nancy L., Saccone, Scott F., Bertelsen, Sarah, Fox, Louis, Horton, William J., Breslau, Naomi, Budde, John, Cloninger, C. Robert, Dick, Danielle M., Foroud, Tatiana, Hatsukami, Dorothy, Hesselbrock, Victor, Johnson, Eric O., Kramer, John, Kuperman, Samuel, Madden, Pamela A.F., Mayo, Kevin, Nurnberger, John, Pomerleau, Ovide, Porjesz, Bernice, Reyes, Oliver, Schuckit, Marc, Swan, Gary, Tischfield, Jay A., Edenberg, Howard J., Rice, John P., Goate, Alison M.

“…Objective: A recent study provisionally identified numerous genetic variants as risk factors for the transition from smoking to the development of nicotine…”
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Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis by Macgregor, Stuart, Lind, Penelope A., Bucholz, Kathleen K., Hansell, Narelle K., Madden, Pamela A.F., Richter, Melinda M., Montgomery, Grant W., Martin, Nicholas G., Heath, Andrew C., Whitfield, John B.

“…Alcohol dependence (AD) is a complex disorder with environmental and genetic origins. The role of two genetic variants in ALDH2 and ADH1B in AD risk has been…”
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The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design by Iacono, William G., Heath, Andrew C., Hewitt, John K., Neale, Michael C., Banich, Marie T., Luciana, Monica M., Madden, Pamela A., Barch, Deanna M., Bjork, James M.

“…The ABCD twin study will elucidate the genetic and environmental contributions to a wide range of mental and physical health outcomes in children, including…”
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Metabolic and Biochemical Effects of Low-to-Moderate Alcohol Consumption by Whitfield, John B., Heath, Andrew C., Madden, Pamela A. F., Pergadia, Michele L., Montgomery, Grant W., Martin, Nicholas G.

“…Background Alcohol consumption has multiple biochemical consequences. Only a few of these are useful as diagnostic markers, but many reflect potentially…”
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Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study by Tielbeek, Jorim J, Medland, Sarah E, Benyamin, Beben, Byrne, Enda M, Heath, Andrew C, Madden, Pamela A F, Martin, Nicholas G, Wray, Naomi R, Verweij, Karin J H

“…Crime poses a major burden for society. The heterogeneous nature of criminal behavior makes it difficult to unravel its causes. Relatively little research has…”
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A genome-wide association study of sleep habits and insomnia by Byrne, Enda M., Gehrman, Philip R., Medland, Sarah E., Nyholt, Dale R., Heath, Andrew C., Madden, Pamela A. F., Hickie, Ian B., Van Duijn, Cornelia M., Henders, Anjali K., Montgomery, Grant W., Martin, Nicholas G., Wray, Naomi R.

“…Several aspects of sleep behavior such as timing, duration and quality have been demonstrated to be heritable. To identify common variants that influence sleep…”
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Childhood sexual abuse and early substance use in adolescent girls: the role of familial influences by Sartor, Carolyn E., Waldron, Mary, Duncan, Alexis E., Grant, Julia D., McCutcheon, Vivia V., Nelson, Elliot C., Madden, Pamela A. F., Bucholz, Kathleen K., Heath, Andrew C.

“…Aim To assess the extent to which the association between childhood sexual abuse (CSA) and early use of alcohol, cigarettes and cannabis in adolescent girls is…”
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The Human Epigenome Browser at Washington University by Zhou, Xin, Maricque, Brett, Xie, Mingchao, Li, Daofeng, Sundaram, Vasavi, Martin, Eric A, Koebbe, Brian C, Nielsen, Cydney, Hirst, Martin, Farnham, Peggy, Kuhn, Robert M, Zhu, Jingchun, Smirnov, Ivan, Kent, W James, Haussler, David, Madden, Pamela A F, Costello, Joseph F, Wang, Ting

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Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders by Ligthart, Lannie, Hottenga, Jouke-Jan, Lewis, Cathryn M., Farmer, Anne E., Craig, Ian W., Breen, Gerome, Willemsen, Gonneke, Vink, Jacqueline M., Middeldorp, Christel M., Byrne, Enda M., Heath, Andrew C., Madden, Pamela A. F., Pergadia, Michele L., Montgomery, Grant W., Martin, Nicholas G., Penninx, Brenda W. J. H., McGuffin, Peter, Boomsma, Dorret I., Nyholt, Dale R.

“…Migraine and major depressive disorder (MDD) are comorbid, moderately heritable and to some extent influenced by the same genes. In a previous paper, we…”
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Maternal alcohol use disorder and offspring ADHD: disentangling genetic and environmental effects using a children-of-twins design by Knopik, Valerie S, Heath, Andrew C, Jacob, Theodore, Slutske, Wendy S, Bucholz, Kathleen K, Madden, Pamela A F, Waldron, Mary, Martin, Nicholas G

“…Children of alcoholics are significantly more likely to experience high-risk environmental exposures, including prenatal substance exposure, and are more…”
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A latent class analysis of illicit drug abuse/dependence: results from the National Epidemiological Survey on Alcohol and Related Conditions by Agrawal, Arpana, Lynskey, Michael T., Madden, Pamela A. F., Bucholz, Kathleen K., Heath, Andrew C.

“…ABSTRACT Aims  We examine the co‐occurrence of abuse/dependence across different illicit drugs and test associations between these classes and major…”
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Genome-wide Linkage and Association Analyses Implicate FASN in Predisposition to Uterine Leiomyomata by EGGERT, Stacey L, HUYCK, Karen L, TRELOAR, Susan A, ZONDERVAN, Krina T, HEATH, Andrew C, MADDEN, Pamela A. F, ROSE, Lynda, BURING, JulieE, RIDKER, Paul M, CHASMAN, Daniel I, MARTIN, Nicholas G, CANTOR, Rita M, SOMASUNDARAM, Priya, MORTON, Cynthia C, KAVALLA, Raghava, STEWART, Elizabeth A, LU, Ake T, PAINTER, Jodie N, MONTGOMERY, Grant W, MEDLAND, Sarah E, NYHOLT, Dale R

“…Uterine leiomyomata (UL), the most prevalent pelvic tumors in women of reproductive age, pose a major public health problem given their high frequency,…”
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