Search Results - "Madden, Katherine G."
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Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden
Published in Journal for immunotherapy of cancer (09-05-2018)“…Immune checkpoint inhibitors (ICIs) have changed the clinical management of melanoma. However, not all patients respond, and current biomarkers including PD-L1…”
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Journal Article -
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Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients
Published in Journal for immunotherapy of cancer (01-02-2019)“…Resistance to immune checkpoint inhibitors (ICIs) has been linked to local immunosuppression independent of major ICI targets (e.g., PD-1). Clinical experience…”
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Journal Article -
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Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors
Published in Journal for immunotherapy of cancer (24-01-2019)“…PD-L1 immunohistochemistry (IHC) has been traditionally used for predicting clinical responses to immune checkpoint inhibitors (ICIs). However, there are at…”
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Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients
Published in Oncoimmunology (01-01-2020)“…Biomarkers predicting immunotherapy response in metastatic renal cell cancer (mRCC) are lacking. PD-L1 immunohistochemistry is a complementary diagnostic for…”
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