Search Results - "Madden, Joseph C."
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Zika Virus Infection Induces DNA Damage Response in Human Neural Progenitors That Enhances Viral Replication
Published in Journal of virology (15-10-2019)“…Zika virus (ZIKV) infection attenuates the growth of human neural progenitor cells (hNPCs). As these hNPCs generate the cortical neurons during early brain…”
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Insertion position as well as the inserted TRS and gene sequences differentially affect the retention of foreign gene expression by simian hemorrhagic fever virus (SHFV)
Published in Virology (New York, N.Y.) (01-12-2018)“…Recombinant SHFV infectious cDNA clones expressing a foreign gene from an additional sg mRNA were constructed. Two 3′ genomic region sites, between ORF4′ and…”
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Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus
Published in Proceedings of the National Academy of Sciences - PNAS (17-10-2017)“…Members of the order Nidovirales express their structural protein ORFs from a nested set of 3′ subgenomic mRNAs (sg mRNAs), and for most of these ORFs, a…”
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Effectiveness of two and three mRNA COVID‐19 vaccine doses against Omicron‐ and Delta‐Related outpatient illness among adults, October 2021–February 2022
Published in Influenza and other respiratory viruses (01-11-2022)“…Background We estimated SARS‐CoV‐2 Delta‐ and Omicron‐specific effectiveness of two and three mRNA COVID‐19 vaccine doses in adults against symptomatic illness…”
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Assessment of Clinical and Virological Characteristics of SARS-CoV-2 Infection Among Children Aged 0 to 4 Years and Their Household Members
Published in JAMA network open (31-08-2022)“…Importance Few studies have prospectively assessed SARS-CoV-2 community infection in children aged 0 to 4 years. Information about SARS-CoV-2 incidence and…”
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Impact of Age and Symptom Development on SARS-CoV-2 Transmission in Households With Children—Maryland, New York, and Utah, August 2020–October 2021
Published in Open forum infectious diseases (01-08-2022)“…Abstract Background Households are common places for spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We investigated factors associated…”
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Genomic Surveillance for SARS-CoV-2 Variants: Predominance of the Delta (B.1.617.2) and Omicron (B.1.1.529) Variants - United States, June 2021-January 2022
Published in MMWR. Morbidity and mortality weekly report (11-02-2022)“…Genomic surveillance is a critical tool for tracking emerging variants of SARS-CoV-2 (the virus that causes COVID-19), which can exhibit characteristics that…”
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