Search Results - "Madden, C. J."

Neurons in the paraventricular nucleus of the hypothalamus inhibit sympathetic outflow to brown adipose tissue by Madden, C J, Morrison, S F

“…The paraventricular nucleus of the hypothalamus (PVH) plays an important role in energy homeostasis, regulating neuroendocrine, behavioral, and autonomic…”
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Glucoprivation in the ventrolateral medulla decreases brown adipose tissue sympathetic nerve activity by decreasing the activity of neurons in raphe pallidus by Madden, C J

“…In urethane/α-chloralose anesthetized rats, cold exposure increased brown adipose tissue sympathetic nerve activity (BAT SNA: +699 ± 104% control). Intravenous…”
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RNase L Antiviral Activity Is Not a Critical Component of the Oas1b-Mediated Flavivirus Resistance Phenotype by Madden, Jr, J C, Cui, Dan, Brinton, M A

“…In mice, resistance to central nervous system (CNS) disease induced by members of the genus is conferred by an allele of the 2'-5' oligoadenylate synthetase 1b…”
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Hepatotoxicity: A scheme for generating chemical categories for read-across, structural alerts and insights into mechanism(s) of action by Hewitt, M., Enoch, S. J., Madden, J. C., Przybylak, K. R., Cronin, M. T. D.

“…Abstract The ability of a compound to cause adverse effects to the liver is one of the most common reasons for drug development failures and the withdrawal of…”
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The Potential Role of Plant Oxygen and Sulphide Dynamics in Die-off Events of the Tropical Seagrass, Thalassia testudinum by Borum, J., Pedersen, O., Greve, T. M., Frankovich, T. A., Zieman, J. C., Fourqurean, J. W., Madden, C. J.

“…1 Oxygen and sulphide dynamics were examined, using microelectrode techniques, in meristems and rhizomes of the seagrass Thalassia testudinum at three…”
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Longitudinal changes of structural connectivity in traumatic axonal injury by WANG, J. Y, BAKHADIROV, K, ABDI, H, DEVOUS, M. D, MARQUEZ DE LA PLATA, C. D, MOORE, C, MADDEN, C. J, DIAZ-ARRASTIA, R

“…To identify structural connectivity change occurring during the first 6 months after traumatic brain injury and to evaluate the utility of diffusion tensor…”
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Hypoxic activation of arterial chemoreceptors inhibits sympathetic outflow to brown adipose tissue in rats by Madden, C. J., Morrison, S. F.

“…In urethane–chloralose anaesthetized, neuromuscularly blocked, artificially ventilated rats, we demonstrated that activation of carotid chemoreceptors…”
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Excitatory amino acid receptors in the dorsomedial hypothalamus mediate prostaglandin-evoked thermogenesis in brown adipose tissue by Madden, C J, Morrison, S F

“…We determined whether the dorsomedial hypothalamus (DMH) plays a role in the thermogenic, metabolic, and cardiovascular effects evoked by centrally…”
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In Silico Prediction of Aqueous Solubility: The Solubility Challenge by Hewitt, M, Cronin, M. T. D, Enoch, S. J, Madden, J. C, Roberts, D. W, Dearden, J. C

“…The dissolution of a chemical into water is a process fundamental to both chemistry and biology. The persistence of a chemical within the environment and the…”
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Beyond the word and image: characteristics of a common meaning system for language and vision revealed by functional and structural imaging by Jouen, A.L., Ellmore, T.M., Madden, C.J., Pallier, C., Dominey, P.F., Ventre-Dominey, J.

“…This research tests the hypothesis that comprehension of human events will engage an extended semantic representation system, independent of the input modality…”
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Assessment of Methods To Define the Applicability Domain of Structural Alert Models by Ellison, C. M., Sherhod, R., Cronin, M. T. D., Enoch, S. J., Madden, J. C., Judson, P. N.

“…It is important that in silico models for use in chemical safety legislation, such as REACH, are compliant with the OECD Principles for the Validation of…”
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Classification of chemicals according to mechanism of aquatic toxicity: An evaluation of the implementation of the Verhaar scheme in Toxtree by Enoch, S.J., Hewitt, M., Cronin, M.T.D., Azam, S., Madden, J.C.

“…A number of mechanisms have been identified that can lead to (acute) aquatic toxicity. The assignment of compounds to a particular mechanism of action is…”
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An evaluation of global QSAR models for the prediction of the toxicity of phenols to Tetrahymena pyriformis by Enoch, S.J., Cronin, M.T.D., Schultz, T.W., Madden, J.C.

“…This study presents an analysis of the ability of a two-parameter response surface, a multiple linear regression and a neural network model to produce global…”
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Synergistic effects of high temperature and sulfide on tropical seagrass by Koch, M.S., Schopmeyer, S., Kyhn-Hansen, C., Madden, C.J.

“…To examine the synergism of high temperature and sulfide on two dominant tropical seagrass species, a large-scale mesocosm experiment was conducted in which…”
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Excitatory amino acid receptor activation in the raphe pallidus area mediates prostaglandin-evoked thermogenesis by Madden, C.J, Morrison, S.F

“…To investigate the role of excitatory amino acid neurotransmission within the rostral raphe pallidus area (RPa) in thermogenic and cardiovascular responses,…”
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Tropical seagrass species tolerance to hypersalinity stress by Koch, M.S., Schopmeyer, S.A., Kyhn-Hansen, C., Madden, C.J., Peters, J.S.

“…The long-term sustainability of seagrasses in the subtropics and tropics depends on their ability to adapt to shifts in salinity regimes, particularly in light…”
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Irradiance, Water Column O2, and Tide Drive Internal O2 Dynamics and Meristem H2S Detection in the Dominant Caribbean-Tropical Atlantic Seagrass, Thalassia testudinum by Koch, M. S., Johnson, C. R., Madden, C. J., Pedersen, O.

“…Water column hypoxia, low partial pressure of oxygen (pO 2 ), and hydrogen sulfide (H 2 S) intrusion, a phytotoxin, are factors linked to global seagrass…”
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Database of published retention factors for immobilized artificial membrane HPLC and an assessment of the effect of experimental variability by Ledbetter, M.R., Gutsell, S., Hodges, G., Madden, J.C., O'Connor, S., Cronin, M.T.D.

“…A database was collated of published experimental logarithmic values for the relative retention factors (log kIAM) measured using an immobilized artificial…”
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Molecular fingerprint-derived similarity measures for toxicological read-across: Recommendations for optimal use by Mellor, C.L., Marchese Robinson, R.L., Benigni, R., Ebbrell, D., Enoch, S.J., Firman, J.W., Madden, J.C., Pawar, G., Yang, C., Cronin, M.T.D.

“…Computational approaches are increasingly used to predict toxicity due, in part, to pressures to find alternatives to animal testing. Read-across is the “new…”
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Application of a chemical reactivity database to predict toxicity for reactive mechanisms by Schwöbel, JAH, Madden, JC, Cronin, MTD

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