Search Results - "Maddalena Di Fiore, Maria"

Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia by Di Fiore, Maria Maddalena, Santillo, Alessandra, Falvo, Sara, Longobardi, Salvatore, Chieffi Baccari, Gabriella

“…A bulk of evidence suggests that d-aspartate (d-Asp) regulates steroidogenesis and spermatogenesis in vertebrate testes. This review article focuses on…”
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D-Aspartate Upregulates DAAM1 Protein Levels in the Rat Testis and Induces Its Localization in Spermatogonia Nucleus by Venditti, Massimo, Santillo, Alessandra, Falvo, Sara, Fiore, Maria Maddalena Di, Baccari, Gabriella Chieffi, Minucci, Sergio

“…Cell differentiation during spermatogenesis requires a proper actin dynamic, regulated by several proteins, including formins. Disheveled-Associated-Activator…”
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Evidence for the involvement of d-aspartic acid in learning and memory of rat by Topo, Enza, Soricelli, Andrea, Di Maio, Angela, D'Aniello, Enrico, Di Fiore, Maria Maddalena, D'Aniello, Antimo

“…d-Aspartic acid (d-Asp) is an endogenous amino acid present in neuroendocrine systems. Here, we report evidence that d-Asp in the rat is involved in learning…”
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Polystyrene microplastics impair the functions of cultured mouse Leydig (TM3) and Sertoli (TM4) cells by inducing mitochondrial-endoplasmic reticulum damage by Grillo, Giulia, Falvo, Sara, Latino, Debora, Chieffi Baccari, Gabriella, Venditti, Massimo, Di Fiore, Maria Maddalena, Minucci, Sergio, Santillo, Alessandra

“…Many laboratory studies demonstrated that the exposure to microplastics causes testosterone deficiency and spermatogenic impairment in mammals; however, the…”
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Seasonal changes and sexual dimorphism in gene expression of StAR protein, steroidogenic enzymes and sex hormone receptors in the frog brain by Santillo, Alessandra, Falvo, Sara, Maddalena Di Fiore, Maria, Chieffi Baccari, Gabriella

“…Graphical abstract…”
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D-Asp upregulates PREP and GluA2/3 expressions and induces p-ERK1/2 and p-Akt in rat testis by Santillo, Alessandra, Venditti, Massimo, Minucci, Sergio, Chieffi Baccari, Gabriella, Falvo, Sara, Rosati, Luigi, Di Fiore, Maria Maddalena

“…D-Aspartate (D-Asp) is an endogenous amino acid that plays a central role in the development of the central nervous system (CNS) and functioning of the…”
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Evidence of the protective role of D-Aspartate in counteracting/preventing cadmium-induced oxidative stress in the rat testis by Venditti, Massimo, Santillo, Alessandra, Latino, Debora, Ben Rhouma, Mariem, Romano, Maria Zelinda, Haddadi, Asma, Di Fiore, Maria Maddalena, Minucci, Sergio, Messaoudi, Imed, Chieffi Baccari, Gabriella

“…Cadmium (Cd), by producing oxidative stress and acting as an endocrine disruptor, is known to cause severe testicular injury, documented by histological and…”
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New Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications by Usiello, Alessandro, Di Fiore, Maria Maddalena, De Rosa, Arianna, Falvo, Sara, Errico, Francesco, Santillo, Alessandra, Nuzzo, Tommaso, Chieffi Baccari, Gabriella

“…The endogenous amino acids serine and aspartate occur at high concentrations in free D-form in mammalian organs, including the central nervous system and…”
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D-Aspartate Induces Proliferative Pathways in Spermatogonial GC-1 Cells by Santillo, Alessandra, Falvo, Sara, Chieffi, Paolo, Di Fiore, Maria Maddalena, Senese, Rosalba, Chieffi Baccari, Gabriella

“…D‐aspartate (D‐Asp) is an endogenous amino acid present in vertebrate tissues, with particularly high levels in the testis. In vivo studies indicate that D‐Asp…”
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d-aspartate affects NMDA receptor-extracellular signal–regulated kinase pathway and upregulates androgen receptor expression in the rat testis by Santillo, Alessandra, Falvo, Sara, Chieffi, Paolo, Burrone, Lavinia, Chieffi Baccari, Gabriella, Longobardi, Salvatore, Di Fiore, Maria Maddalena

“…Previous studies have demonstrated that d-aspartic acid (d-Asp) has a role in regulating the release and synthesis of testosterone in rats. In this study, we…”
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D-Aspartic Acid in Vertebrate Reproduction: Animal Models and Experimental Designs by Di Fiore, Maria Maddalena, Boni, Raffaele, Santillo, Alessandra, Falvo, Sara, Gallo, Alessandra, Esposito, Sabrina, Baccari, Gabriella Chieffi

“…This article reviews the animal models and experimental designs that have been used during the past twenty years to demonstrate the prominent role played by…”
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Sex hormone levels in the brain of d-aspartate-treated rats by Di Fiore, Maria Maddalena, Santillo, Alessandra, Falvo, Sara, Chieffi Baccari, Gabriella, Venditti, Massimo, Di Giacomo Russo, Federica, Lispi, Monica, D'Aniello, Antimo

“…d-Aspartate (d-Asp) is an endogenous amino acid present in the central nervous system and endocrine glands of various animal taxa. d-Asp is implicated in…”
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Steroidogenic gene expression following d -aspartate treatment in frog testis by Burrone, Lavinia, Raucci, Franca, Di Fiore, Maria Maddalena

“…Highlights ► In Pelophylax esculentus testis, StAR, P450 aromatase and 5α-reductase mRNA levels change during annual cycle. ► d -Asp treatment increases StAR…”
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Potential role of mitochondria and endoplasmic reticulum in the response elicited by D-aspartate in TM4 Sertoli cells by Falvo, Sara, Grillo, Giulia, Latino, Debora, Chieffi Baccari, Gabriella, Di Fiore, Maria Maddalena, Venditti, Massimo, Petito, Giuseppe, Santillo, Alessandra

“…D-Aspartic Acid (D-Asp) affects spermatogenesis by enhancing the biosynthesis of the sex steroid hormones acting either through the…”
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The Aromatase-Estrogen System in the Testes of Non-Mammalian Vertebrates by Rosati, Luigi, Falvo, Sara, Chieffi Baccari, Gabriella, Santillo, Alessandra, Di Fiore, Maria Maddalena

“…Estrogens are important physiological regulators of testicular activity in vertebrates. Estrogen levels depend on the activity of P450 aromatase, the enzyme…”
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Induced synthesis of P450 aromatase and 17β-estradiol by D-aspartate in frog brain by Burrone, Lavinia, Santillo, Alessandra, Pinelli, Claudia, Baccari, Gabriella Chieffi, Di Fiore, Maria Maddalena

“…D-Aspartic acid is an endogenous amino acid occurring in the endocrine glands as well as in the nervous system of various animal phyla. Our previous studies…”
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Steroidogenesis Upregulation through Mitochondria-Associated Endoplasmic Reticulum Membranes and Mitochondrial Dynamics in Rat Testes: The Role of D-Aspartate by Latino, Debora, Venditti, Massimo, Falvo, Sara, Grillo, Giulia, Santillo, Alessandra, Messaoudi, Imed, Ben Rhouma, Mariem, Minucci, Sergio, Chieffi Baccari, Gabriella, Di Fiore, Maria Maddalena

“…Mitochondria-Associated Endoplasmic Reticulum Membranes (MAMs) mediate the communication between the Endoplasmic Reticulum (ER) and the mitochondria, playing a…”
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Proliferative and Apoptotic Pathways in the Testis of Quail Coturnix coturnix during the Seasonal Reproductive Cycle by Falvo, Sara, Rosati, Luigi, Di Fiore, Maria Maddalena, Di Giacomo Russo, Federica, Chieffi Baccari, Gabriella, Santillo, Alessandra

“…The quail Coturnix coturnix is a seasonal breeding species, with the annual reproductive cycle of its testes comprising an activation phase and a regression…”
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The reproductive activity in the testis of Podarcis s. sicula involves d -aspartic acid: A study on c-kit receptor protein, tyrosine kinase activity and PCNA protein during annual sexual cycle by Raucci, Franca, Fiore, Maria Maddalena Di

“…Abstract The current study provides substantial evidence that the pattern of synthesis of d -aspartic acid ( d -Asp) in the testes of lizard Podarcis s. sicula…”
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d-Asp: A new player in reproductive endocrinology of the amphibian Rana esculenta by Raucci, Franca, Di Fiore, Maria Maddalena

“…We investigated the involvement of d-Aspartic acid ( d-Asp) on ovarian and testicular morphology of the green frog, Rana esculenta, and its effect on the…”
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