Search Results - "Maddalena, Desmond J."

Prediction of Receptor Properties and Binding Affinity of Ligands to Benzodiazepine/GABAA Receptors Using Artificial Neural Networks by Maddalena, Desmond J, Johnston, Graham A. R

“…To date the use of artificial neural networks (ANNs) in quantitative structure-activity relationship (QSAR) studies has been primarily concerned in comparing…”
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Pharmacokinetic parameter prediction from drug structure using artificial neural networks by Turner, Joseph V, Maddalena, Desmond J, Cutler, David J

“…Simple methods for determining the human pharmacokinetics of known and unknown drug-like compounds is a much sought-after goal in the pharmaceutical industry…”
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Bioavailability prediction based on molecular structure for a diverse series of drugs by Turner, Joseph V, Maddalena, Desmond J, Agatonovic-Kustrin, Snezana

“…Radial basis function artificial neural networks and theoretical descriptors were used to develop a quantitative structure-pharmacokinetic relationship for…”
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Multiple pharmacokinetic parameter prediction for a series of cephalosporins by Turner, Joseph V, Maddalena, Desmond J, Cutler, David J, Agatonovic-Kustrin, Snezana

“…The goal of quantitative structure-pharmacokinetic relationship analyses is to develop useful models that can predict one or more pharmacokinetic properties of…”
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Selective descriptor pruning for QSAR/QSPR studies using artificial neural networks by Turner, Joseph V., Cutler, David J., Spence, Ian, Maddalena, Desmond J.

“…Selection of optimal descriptors in quantitative structure–activity–property relationship (QSAR/QSPR) studies has been a perennial problem. Artificial Neural…”
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Synthesis and characterization of potential tumor scintigraphic agents by Awaluddin, A B, Jacobs, J J, Bourne, D W, Maddalena, D J, Wilson, J G, Boyd, R E

“…Potential tumor imaging radiopharmaceutical agents have been prepared by attaching a cisplatin derivative to a ligand capable of forming a stable complex with…”
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