Search Results - "Madathil, Manikandadas M."

The Dynamic Character of the BCL2 Promoter i‑Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure by Kendrick, Samantha, Kang, Hyun-Jin, Alam, Mohammad P, Madathil, Manikandadas M, Agrawal, Prashansa, Gokhale, Vijay, Yang, Danzhou, Hecht, Sidney M, Hurley, Laurence H

“…It is generally accepted that DNA predominantly exists in duplex form in cells. However, under torsional stress imposed by active transcription, DNA can assume…”
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Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro by Maini, Rumit, Dedkova, Larisa M, Paul, Rakesh, Madathil, Manikandadas M, Chowdhury, Sandipan Roy, Chen, Shengxi, Hecht, Sidney M

“…Plasmids containing 23S rRNA randomized at positions 2057–2063 and 2502–2507 were introduced into Escherichia coli, affording a library of clones which…”
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Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA–Protein Interaction by Talukder, Poulami, Chen, Shengxi, Roy, Basab, Yakovchuk, Petro, Spiering, Michelle M, Alam, Mohammad P, Madathil, Manikandadas M, Bhattacharya, Chandrabali, Benkovic, Stephen J, Hecht, Sidney M

“…Described herein are the syntheses and photophysical characterization of three novel cyanotryptophans, and their efficient incorporation into proteins as…”
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Modified Bleomycin Disaccharides Exhibiting Improved Tumor Cell Targeting by Madathil, Manikandadas M, Bhattacharya, Chandrabali, Yu, Zhiqiang, Paul, Rakesh, Rishel, Michael J, Hecht, Sidney M

“…The bleomycins (BLMs) are a family of antitumor antibiotics used clinically for anticancer chemotherapy. Their antitumor selectivity derives at least in part…”
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Correction to “The Dynamic Character of the BCL2 Promoter i‑Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure” by Kendrick, Samantha, Kang, Hyun-Jin, Alam, Mohammad P, Madathil, Manikandadas M, Agrawal, Prashansa, Gokhale, Vijay, Yang, Danzhou, Hecht, Sidney M, Hurley, Laurence H

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Synthesis and Biological Activities of N‑(3-Carboxylpropyl)-5-amino-2-hydroxy-3-tridecyl-1,4-benzoquinone and Analogues by Madathil, Manikandadas M, Khdour, Omar M, Jaruvangsanti, Jennifer, Hecht, Sidney M

“…The synthesis of benzoquinone natural product 2 and three analogues is described. The synthesized compounds were tested for their ability to protect…”
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Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection by Arce, Pablo M., Goldschmidt, Ruth, Khdour, Omar M., Madathil, Manikandadas M., Jaruvangsanti, Jennifer, Dey, Sriloy, Fash, David M., Armstrong, Jeffrey S., Hecht, Sidney M.

“…Selected pyridinol analogues of the experimental neuroprotective drug idebenone have been synthesized and evaluated as antioxidants capable of preserving…”
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A Structurally Simplified Analogue of Geldanamycin Exhibits Neuroprotective Activity by Madathil, Manikandadas M, Khdour, Omar M, Jaruvangsanti, Jennifer, Hecht, Sidney M

“…The syntheses of a structurally simplified geldanamycin analogue 2 and two related compounds are described. Compound 2 conferred cytoprotection and quenched…”
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