Search Results - "Madariaga Mazón, Abraham"

α‑Glucosidase Inhibitors from Preussia minimoides by Rangel-Grimaldo, Manuel, Rivero-Cruz, Isabel, Madariaga-Mazón, Abraham, Figueroa, Mario, Mata, Rachel

“…Extensive fractionation of an extract from the grain-based culture of the endophytic fungus Preussia minimoides led to the isolation of two new polyketides…”
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DARK Classics in Chemical Neuroscience: Salvinorin A by Hernández-Alvarado, R. Bruno, Madariaga-Mazón, Abraham, Ortega, Alfredo, Martinez-Mayorga, Karina

“…Salvinorin A is the main bioactive compound in Salvia divinorum, an endemic plant with ancestral use by the inhabitants of the Mazateca mountain range (Sierra…”
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α‑Glucosidase Inhibitors from Malbranchea flavorosea by Verastegui-Omaña, Brisa, Rebollar-Ramos, Daniela, Pérez-Vásquez, Araceli, Martínez, Ana Laura, Madariaga-Mazón, Abraham, Flores-Bocanegra, Laura, Mata, Rachel

“…From an extract prepared from the grain-based culture of Malbranchea flavorosea two new polyketides, namely, 8-chloroxylarinol A (1) and flavoroseoside (2),…”
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Calmodulin Inhibitors from Natural Sources: An Update by Mata, Rachel, Figueroa, Mario, González-Andrade, Martín, Rivera-Chávez, José Alberto, Madariaga-Mazón, Abraham, Del Valle, Paulina

“…Calmodulin (CaM) plays a central role in regulating a myriad of cellular functions in physiological and pathophysiological processes, thus representing an…”
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Absolute Configuration of Acremoxanthone C, a Potent Calmodulin Inhibitor from Purpureocillium lilacinum by Madariaga-Mazón, Abraham, González-Andrade, Martín, González, María del Carmen, Glenn, Anthony E, Cerda-García-Rojas, Carlos M, Mata, Rachel

“…Bioassay-guided fractionation of an extract prepared from the culture medium and mycelium of Purpureocillium lilacinum allowed the isolation of two calmodulin…”
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Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics? by Madariaga-Mazón, Abraham, Marmolejo-Valencia, Andrés F., Li, Yangmei, Toll, Lawrence, Houghten, Richard A., Martinez-Mayorga, Karina

“…•μ-OR biased agonists represent promising analgesics with improved therapeutic profiles.•Protein-ligand interactions might account for biased ligands…”
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Antidiabetic Potential of a Trimeric Anthranilic Acid Peptide Isolated from Malbranchea flocciformis by Rebollar‐Ramos, Daniela, Ovalle‐Magallanes, Berenice, Raja, Huzefa A., Jacome‐Rebollo, Mariano, Figueroa, Mario, Tovar‐Palacio, Claudia, Noriega, Lilia G., Madariaga‐Mazón, Abraham, Mata, Rachel

“…Compound 3, a trimeric anthranilic acid peptide, and another three metabolites were isolated from an organic extract from the culture medium of Malbranchea…”
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Discovery of inhibitors of protein tyrosine phosphatase 1B contained in a natural products library from Mexican medicinal plants and fungi using a combination of enzymatic and in silico methods by Díaz-Rojas, Miriam, González-Andrade, Martin, Aguayo-Ortiz, Rodrigo, Rodríguez-Sotres, Rogelio, Pérez-Vásquez, Araceli, Madariaga-Mazón, Abraham, Mata, Rachel

“…This work aimed to discover protein tyrosine phosphatase 1B (PTP1B) inhibitors from a small molecule library of natural products (NPs) derived from selected…”
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Encoding mu-opioid receptor biased agonism with interaction fingerprints by Hernández-Alvarado, R. Bruno, Madariaga-Mazón, Abraham, Cosme-Vela, Fernando, Marmolejo-Valencia, Andrés F., Nefzi, Adel, Martinez-Mayorga, Karina

“…Opioids are potent painkillers, however, their therapeutic use requires close medical monitoring to diminish the risk of severe adverse effects. The G-protein…”
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Lipase inhibitory activity of constituents of Physalis glutinosa and Physalis latiphysa by Maldonado, Emma, Mineros, Areli, Torres, Oscar D., Ovalle-Magallanes, Berenice, Madariaga-Mazón, Abraham, Pérez-Castorena, Ana L., Martínez, Mahinda

“…The new labdane-type diterpenoid, physaglutinic acid ( 1 ), was isolated from the hexane extract of Physalis glutinosa . This compound is the first succinyl…”
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Identification of Potential Inhibitors of Mycobacterium tuberculosis Amidases: An Integrated In Silico and Experimental Study by Rosas-Cruz, Maciel, Madariaga Mazón, Abraham, García-Mejía, Carlos D., Hernández-Vázquez, Eduardo, Gómez-Velasco, Homero, Jiménez-Faraco, Eva, Farías-Gaytán, Roberto Sealtiel, Hermoso, Juan A., Martínez-Caballero, Siseth

“…Virtual screening is a crucial tool in early stage drug discovery for identifying potential hit candidates. Here, we present an integrated approach that…”
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Insights on the vasorelaxant mode of action of malbrancheamide by Madariaga-Mazón, Abraham, Hernández-Abreu, Oswaldo, Estrada-Soto, Samuel, Mata, Rachel

“…Objectives This study was conducted to evaluate the vasorelaxant effect of the fungal alkaloids malbrancheamides on pre‐contracted rat aorta rings. Also, we…”
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Subtle structural differences of nucleotide analogs may impact SARS-CoV-2 RNA-dependent RNA polymerase and exoribonuclease activity by Madariaga-Mazón, Abraham, Naveja, José J., Becerra, Arturo, Alberto Campillo-Balderas, José, Hernández-Morales, Ricardo, Jácome, Rodrigo, Lazcano, Antonio, Martinez-Mayorga, Karina

“…[Display omitted] The rapid spread and public health impact of the novel SARS-CoV-2 variants that cause COVID-19 continue to produce major global impacts and…”
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Bias-inducing allosteric binding site in mu-opioid receptor signaling by Marmolejo-Valencia, Andrés F., Madariaga-Mazón, Abraham, Martinez-Mayorga, Karina

“…G-protein-biased agonism of the mu-opioid receptor (μ-OR) is emerging as a promising strategy in analgesia. A deep understanding of how biased agonists…”
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Importance of the interaction protein-protein of the CaM-PDE1A and CaM-MLCK complexes in the development of new anti-CaM drugs by González-Andrade, Martin, Mata, Rachel, Madariaga-Mazón, Abraham, Rodríguez-Sotres, Rogelio, del Pozo-Yauner, Luis, Sosa-Peinado, Alejandro

“…Protein–protein interactions play central roles in physiological and pathological processes. The bases of the mechanisms of drug action are relevant to the…”
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DiaNat-DB: a molecular database of antidiabetic compounds from medicinal plants by Madariaga-Mazón, Abraham, Naveja, José J, Medina-Franco, José L, Noriega-Colima, Karla O, Martinez-Mayorga, Karina

“…Natural products are an invaluable source of molecules with a large variety of biological activities. Interest in natural products in drug discovery is…”
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Union is strength: antiviral and anti-inflammatory drugs for COVID-19 by Naveja, Jose J., Madariaga-Mazón, Abraham, Flores-Murrieta, Francisco, Granados-Montiel, Julio, Maradiaga-Ceceña, Marco, Alaniz, Víctor Duarte, Maldonado-Rodriguez, Maricruz, García-Morales, Jazmín, Senosiain-Peláez, Juan Pablo, Martinez-Mayorga, Karina

“…[Display omitted] •Treatment for moderately ill COVID-19 patients might arise from drug repurposing•RdRp, spike protein, and Mpro are relevant SARS-CoV-2…”
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Protein tyrosine phosphatase 1B inhibitory activity of compounds from Justicia spicigera (Acanthaceae) by Pérez-Vásquez, Araceli, Díaz-Rojas, Miriam, Castillejos-Ramírez, Erika V., Pérez-Esquivel, Alejandra, Montaño-Cruz, Yullet, Rivero-Cruz, Isabel, Torres-Colín, Rafael, González-Andrade, Martin, Rodríguez-Sotres, Rogelio, Gutiérrez-González, José Alberto, Madariaga-Mazón, Abraham, Mata, Rachel

“…An infusion from the aerial parts of Justicia spicigera Schltdl., an herb commonly used to treat diabetes, inhibited the activity of protein tyrosine…”
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Antidiabetic and Antihyperalgesic Effects of a Decoction and Compounds from Acourtia thurberi by Martínez, Ana Laura, Madariaga-Mazón, Abraham, Rivero-Cruz, Isabel, Bye, Robert, Mata, Rachel

“…The purpose of this research was to examine the preclinical efficacy of a decoction from the roots of as a hypoglycemic, antihyperglycemic, and…”
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Network Pharmacology Uncovers Anticancer Activity of Mammea-Type Coumarins from Calophyllum brasiliense by Gómez-Verjan, Juan Carlos, Rivero-Segura, Nadia Alejandra, Estrella-Parra, Edgar, Rincón-Heredia, Ruth, Madariaga-Mazón, Abraham, Flores-Soto, Edgar, González-Meljem, Mario, Cerbón, Marco, Reyes-Chilpa, Ricardo

“…Mammea-type coumarins are a particular type of secondary metabolites biosynthesized by the tropical rainforest tree , which is distributed from South America…”
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