Search Results - "Madar, Igal"

Stable delineation of the ischemic area by the PET perfusion tracer 18F-fluorobenzyl triphenyl phosphonium after transient coronary occlusion by Higuchi, Takahiro, Fukushima, Kenji, Rischpler, Christoph, Isoda, Takuro, Javadi, Mehrbod S, Ravert, Hayden, Holt, Daniel P, Dannals, Robert F, Madar, Igal, Bengel, Frank M

“…(18)F-fluorobenzyl triphenyl phosphonium (FBnTP) has recently been introduced as a myocardial perfusion PET agent. We used a rat model of transient coronary…”
Get full text

Brown Adipose Tissue Response Dynamics: In Vivo Insights with the Voltage Sensor 18F-Fluorobenzyl Triphenyl Phosphonium by Madar, Igal, Naor, Elinor, Holt, Daniel, Ravert, Hayden, Dannals, Robert, Wahl, Richard

“…Brown adipose tissue (BAT) thermogenesis is an emerging target for prevention and treatment of obesity. Mitochondria are the heat generators of BAT. Yet, there…”
Get full text

PET imaging of opioid receptors in pain: progress and new directions by Ravert, Hayden T, Bencherif, Badreddine, Madar, Igal, Frost, J James

“…The endogenous opioid system plays a central role in pain. Recent advances have permitted imaging of opioid receptors by PET in human subjects while…”
Get more information

Radiosynthesis of 3-[18F]fluoropropyl and 4-[18F]fluorobenzyl triarylphosphonium ions by Ravert, Hayden T., Madar, Igal, Dannals, Robert F.

“…3‐[18F]Fluoropropyl‐, 4‐[18F]fluorobenzyl‐triphenylphosphonium and 4‐[18F]fluorobenzyltris‐4‐dimethylaminophenylphosphonium cations were synthesized in…”
Get full text

Detection and Quantification of the Evolution Dynamics of Apoptosis Using the PET Voltage Sensor 18F-Fluorobenzyl Triphenyl Phosphonium by Madar, Igal, Huang, Yi, Ravert, Hayden, Dalrymple, Susan L, Davidson, Nancy E, Isaacs, John T, Dannals, Robert F, Frost, J. James

“…Apoptosis is a key mechanism in numerous pathologies. However, there are no effective noninvasive means available for an early detection and quantitative…”
Get full text

Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation by Madar, Igal, Ravert, Hayden, Nelkin, Barry, Abro, Masroor, Pomper, Martin, Dannals, Robert, Frost, James J

“…Mitochondrial dysfunction has been attributed a critical role in the etiology and pathogenesis of numerous diseases, and is manifested by alterations of the…”
Get full text

Brown Adipose Tissue Response Dynamics: In Vivo Insights with the Voltage Sensor .sup.18F-Fluorobenzyl Triphenyl Phosphonium by Madar, Igal, Naor, Elinor, Holt, Daniel, Ravert, Hayden, Dannals, Robert, Wahl, Richard

“…Brown adipose tissue (BAT) thermogenesis is an emerging target for prevention and treatment of obesity. Mitochondria are the heat generators of BAT. Yet, there…”
Get full text

sup 18^F-Fluorobenzyl Triphenyl Phosphonium: A Noninvasive Sensor of Brown Adipose Tissue Thermogenesis by Madar, Igal, Isoda, Takuro, Finley, Paige, Angle, James, Wahl, Richard

“…Recent studies have proposed activation of brown adipose tissue (BAT) thermogenesis as a new strategy to combat obesity. Currently, there is no effective…”
Get full text

18F-fluorobenzyl triphenyl phosphonium: a noninvasive sensor of brown adipose tissue thermogenesis by Madar, Igal, Isoda, Takuro, Finley, Paige, Angle, James, Wahl, Richard

“…Recent studies have proposed activation of brown adipose tissue (BAT) thermogenesis as a new strategy to combat obesity. Currently, there is no effective…”
Get full text

18 F-Fluorobenzyl Triphenyl Phosphonium: A Noninvasive Sensor of Brown Adipose Tissue Thermogenesis by Madar, Igal, Isoda, Takuro, Finley, Paige, Angle, James, Wahl, Richard

Get full text

Compensation for spill-in and spill-out partial volume effects in cardiac PET imaging by Du, Yong, Madar, Igal, Stumpf, Martin J., Rong, Xing, Fung, George S.K., Frey, Eric C.

“…Partial volume effects (PVEs) in PET imaging result in incorrect regional activity estimates due to both spill-out and spill-in from activity in neighboring…”
Get full text

Preferential accumulation of (3)H-tetraphenylphosphonium in non-small cell lung carcinoma in mice: comparison with (99m)Tc-MIBI by Madar, Igal, Weiss, Lola, Izbicki, Gabriel

“…We have previously shown enhanced accumulation of the delocalized lipophilic cation (11)C-triphenylmethylphosphonium in canine brain glioma, suggesting its…”
Get full text

Imaging delta- and mu-opioid receptors by PET in lung carcinoma patients by Madar, Igal, Bencherif, Badreddine, Bencherif, Badredin, Lever, John, Heitmiller, Richard F, Yang, Stephen C, Brock, Malcolm, Brahmer, Julie, Ravert, Hayden, Dannals, Robert, Frost, James J

“…In the present study, we measured the kinetics and distribution in vivo of the selective delta-opioid antagonist 11C-methylnaltrindole (11C-MeNTI) and the…”
Get full text

The Role of P-Glycoprotein in Intestinal Transport versus the BBB Transport of Tetraphenylphosphonium by Swed, Avi, Eyal, Sara, Madar, Igal, Zohar-Kontante, Hila, Weiss, Lola, Hoffman, Amnon

“…Tetraphenylphosphonium (TPP), a phosphonium cation, is a promising means for tumor imaging. A major contributor to the pharmacokinetics of phosphonium cations…”
Get full text

Imaging of ? opioid receptors in human brain by N1?- ([11C]methyl)naltrindole and PET by Madar, Igal, Lever, John R., Kinter, Chris M., Scheffel, Ursula, Ravert, Hayden T., Musachio, John L., Mathews, William B., Dannals, Robert F., Frost, J. James

Get full text

In vivo localization and quantification of mitochondrial dysfunction using PET imaging of the novel voltage sensor 18F-FBnTP by Madar, Igal, Du, Yong, Liu, Ting, Ravert, Hayden, Crow, Michael, Hare, Joshua, O'Rourak, Brian, Wahl, Richard, Dannals, Robert

Get full text

Stable Delineation of the Ischemic Area by the PET Perfusion Tracer 18 F-Fluorobenzyl Triphenyl Phosphonium After Transient Coronary Occlusion by Higuchi, Takahiro, Fukushima, Kenji, Rischpler, Christoph, Isoda, Takuro, Javadi, Mehrbod S., Ravert, Hayden, Holt, Daniel P., Dannals, Robert F., Madar, Igal, Bengel, Frank M.

Get full text

Stable Delineation of the Ischemic Area by the PET Perfusion Tracer ^sup 18^F-Fluorobenzyl Triphenyl Phosphonium After Transient Coronary Occlusion by Higuchi, Takahiro, Fukushima, Kenji, Rischpler, Christoph, Isoda, Takuro, Javadi, Mehrbod S, Ravert, Hayden, Holt, Daniel P, Dannals, Robert F, Madar, Igal, Bengel, Frank M

“…^sup 18^F-fluorobenzyl triphenyl phosphonium (FBnTP) has recently been introduced as a myocardial perfusion PET agent. We used a rat model of transient…”
Get full text

Assessment of Severity of Coronary Artery Stenosis in a Canine Model Using the PET Agent ^sup 18^F-Fluorobenzyl Triphenyl Phosphonium: Comparison with ^sup 99m^Tc-Tetrofosmin by Madar, Igal, Hayden Ravert, DiPaula, Antony, Du, Yong

“…Myocardial perfusion imaging plays an important role in clinical management of coronary artery disease, but the most commonly used radionuclides significantly…”
Get full text

Characterization of Uptake of the New PET Imaging Compound ^sup 18^F-Fluorobenzyl Triphenyl Phosphonium in Dog Myocardium by Madar, Igal, Ravert, Hayden T, Du, Yong, Hilton, John

“…^sup 18^F-Labeled p-fluorobenzyl triphenyl phosphonium cation (^sup 18^F-FBnTP) is a member of a new class of positron-emitting lipophilic cations that may act…”
Get full text