Search Results - "Madanan, Madathiparambil G."

Extracellular Proteome Analysis Shows the Abundance of Histidine Kinase Sensor Protein, DNA Helicase, Putative Lipoprotein Containing Peptidase M75 Domain and Peptidase C39 Domain Protein in Leptospira interrogans Grown in EMJH Medium by Sarma, Abhijit, Gunasekaran, Dhandapani, Rex, Devasahayam Arokia Balaya, Sikha, Thoduvayil, Phukan, Homen, Kiran, Kumar Mangalaparthi, Pinto, Sneha M., Prasad, Thottethodi Subrahmanya Keshava, Madanan, Madathiparambil G.

“…Leptospirosis is a re-emerging form of zoonosis that is caused by the spirochete pathogen Leptospira. Extracellular proteins play critical roles in the…”
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Expression of Leptospira membrane proteins Signal Peptidase (SP) and Leptospira Endostatin like A (Len A) in BL-21(DE3) is toxic to the host cells by Satheeshkumar, Padikara K., Anu, Prasannan V., Junaida, Mohmed I., Madanan, Madathiparambil G., Jebasingh, Tennison, Nair, Ananthakrishnan J., Nair, Gangaprasad A., Nair, Govinda Pillai M., Sudhakaran, Perumana R.

“…Heterologous expression of Integral Membrane Proteins (IMPs) is reported to be toxic to the host system in many studies. Even though there are reports on…”
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Leptospiral cell wall hydrolase (LIC_10271) binding peptidoglycan, lipopolysaccharide, and laminin and the protein show LysM and M23 domains are co-existing in pathogenic species by Sarma, Abhijit, Dhandapani, Gunasekaran, Phukan, Homen, Bhunia, Prasun Kumar, De, Arun Kumar, Bhattacharya, Debasis, Jebasingh, T., Madanan, Madathiparambil G.

“…Leptospirosis, a global reemerging zoonosis caused by the spirochete Leptospira, has severe human and veterinary implications. Cell wall hydrolase (LIC_10271)…”
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Detection and Characterization of Bacterial Proteinases Using Zymography by Madanan, Madathiparambil G, Mechoor, Ambili

“…Proteinases play a crucial role in invasion and pathogenesis of bacteria, especially the extracellular and membrane-bound forms. Analysis of these proteinases…”
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Zymography in Multiwells for Quality Assessment of Proteinases by Mechoor, Ambili, Madanan, Madathiparambil G

“…Zymography is a well-standardized protocol for the qualitative assessment and analysis of proteinases under specified conditions. However, analysis of a large…”
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Triton X‐114 Fractionated Subcellular Proteome of Leptospira interrogans Shows Selective Enrichment of Pathogenic and Outer Membrane Proteins in the Detergent Fraction by Thoduvayil, Sikha, Dhandapani, Gunasekaran, Brahma, Rahul, Devasahayam Arokia Balaya, Rex, Mangalaparthi, Kiran K., Patel, Krishna, Kumar, Manish, Tennyson, Jebasingh, Satheeshkumar, P. K., Kulkarni, Mahesh J., Pinto, Sneha M., Prasad, T. S. Keshava, Madanan, Madathiparambil G.

“…The Triton X‐114‐based solubilization and temperature‐dependent phase separation of proteins is used for subcellular fractionation where, aqueous, detergent,…”
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Comparison of Leptospira interrogans and Leptospira biflexa genomes: analysis of potential leptospiral-host interactions by Mehrotra, Prachi, Ramakrishnan, Gayatri, Dhandapani, Gunasekaran, Srinivasan, Narayanaswamy, Madanan, Madathiparambil G

“…Leptospirosis, a potentially life-threatening disease, remains the most widespread zoonosis caused by pathogenic species of Leptospira. The pathogenic…”
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Heterologous Expression, Purification and Characterization of an Oligopeptidase A from the Pathogen Leptospira interrogans by Anu, Prasannan V., Madanan, Madathiparambil G., Nair, Ananthakrishnan J., Nair, Gangaprasad A., Nair, Govinda Pillai M., Sudhakaran, Perumana R., Satheeshkumar, Padikara K.

“…Oligopeptidases are enzymes involved in the degradation of short peptides (generally less than 30 amino acids in size) which help pathogens evade the host…”
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Molecular modeling and in-silico engineering of Cardamom mosaic virus coat protein for the presentation of immunogenic epitopes of Leptospira LipL32 by Kumar, Vikram, Damodharan, S., Pandaranayaka, Eswari P.J., Madathiparambil, Madanan G., Tennyson, Jebasingh

“…Expression of Cardamom mosaic virus (CdMV) coat protein (CP) in E. coli forms virus-like particles. In this study, the structure of CdMV CP was predicted and…”
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A diagnostically useful 200-kDa protein is secreted through the surface pores of the filarial parasite Setaria digitata by Madathiparambil, Madanan G., Kaleysa, Kavitharaj N., Raghavan, Kaleysaraj

“…The excretory/secretory (ES) materials from filarial parasites form an important tool for immunodiagnosis of filariasis. We have raised monoclonal antibodies…”
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Presence of 46 kDa Gelatinase on the Outer Membrane of Leptospira by Madathiparambil, Madanan G, Cattavarayane, Sandhanakrishnan, Perumana, Sudhakaran R, Manickam, Gayathri D, Sehgal, Subhash C

“…Leptospira infection involves the adhesion of the bacteria followed by invasion of the host crossing the extracellular matrix barrier. In an effort to…”
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Zymography Analysis of Proteinase Activity Present in Leptospira by Madathiparambil, Madanan G, Cattavarayane, Sandhanakrishnan, Manickam, Gayathri D, Singh, Kavita, Perumana, Sudhakaran R, Sehgal, Subhash C

“…Leptospirosis is a major public health problem caused by spirochete Leptospira which is an extracellular pathogen. During infection and invasion, the bacteria…”
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