Search Results - "Madan, Meenu"

Receptor Channel TRPC6 Is a Key Mediator of Notch-Driven Glioblastoma Growth and Invasiveness by CHIGURUPATI, Srinivasulu, VENKATARAMAN, Rajarajeswari, LATHIA, Justin D, RICH, Jeremy N, CHAN, Sic L, BARRERA, Daniel, NAGANATHAN, Anusha, MADAN, Meenu, PAUL, Leena, PATTISAPU, Jogi V, KYRIAZIS, George A, SUGAYA, Kiminobu, BUSHNEV, Sergey

“…Glioblastoma multiforme (GBM) is the most frequent and incurable type of brain tumor of adults. Hypoxia has been shown to direct GBM toward a more aggressive…”
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Expression of Aquaporin 1 and 4 in a Congenital Hydrocephalus Rat Model by Paul, Leena, Madan, Meenu, Rammling, Matthias, Chigurupati, Srinivasulu, Chan, Sic L., Pattisapu, Jogi V.

“…Abstract BACKGROUND: Hydrocephalus occurs because of an imbalance of bulk fluid flow in the brain, and aquaporins (AQPs) play pivotal roles in cerebral water…”
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Stress-induced Switch in Numb Isoforms Enhances Notch-dependent Expression of Subtype-specific Transient Receptor Potential Channel by Kyriazis, George A., Belal, Cherine, Madan, Meenu, Taylor, David G., Wang, Jang, Wei, Zelan, Pattisapu, Jogi V., Chan, Sic L.

“…The Notch signaling pathway plays an essential role in the regulation of cell specification by controlling differentiation, proliferation, and apoptosis. Numb…”
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Evidence for reduced lymphatic CSF absorption in the H-Tx rat hydrocephalus model by Rammling, Matthias, Madan, Meenu, Paul, Leena, Behnam, Babak, Pattisapu, Jogi V

“…There is mounting evidence that spinal fluid absorption takes place not only at the arachnoid villi, but also at several extracranial sites, which might serve…”
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A DESD-box helicase functions in salinity stress tolerance by improving photosynthesis and antioxidant machinery in rice (Oryza sativa L. cv. PB1) by Gill, Sarvajeet Singh, Tajrishi, Marjan, Madan, Meenu, Tuteja, Narendra

“…The exact mechanism of helicase-mediated salinity tolerance is not yet understood. We have isolated a DESD-box containing cDNA from Pisum sativum (Pea) and…”
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The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors by Dobrovolskaite, Aiste, Madan, Meenu, Pandey, Veethika, Altomare, Deborah A., Phanstiel, Otto

“…[Display omitted] •Discovery of first non-polyamine based, polyamine transport inhibitor.•Extensive head to head comparisons of published polyamine transport…”
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Polyamine Transport Inhibitors: Design, Synthesis, and Combination Therapies with Difluoromethylornithine by Muth, Aaron, Madan, Meenu, Archer, Jennifer Julian, Ocampo, Nicolette, Rodriguez, Luis, Phanstiel, Otto

“…The development of polyamine transport inhibitors (PTIs), in combination with the polyamine biosynthesis inhibitor difluoromethylornithine (DFMO), provides a…”
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Proteomics analyses of subcutaneous adipocytes reveal novel abnormalities in human insulin resistance by Xie, Xitao, Yi, Zhengping, Sinha, Sandeep, Madan, Meenu, Bowen, Benjamin P., Langlais, Paul, Ma, Danjun, Mandarino, Lawrence, Meyer, Christian

“…Objective To provide a more global view of adipocyte changes in human insulin resistance by proteomics analyses. Methods Baseline biopsies of abdominal…”
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Neuronal Aquaporin 1 Inhibits Amyloidogenesis by Suppressing the Interaction Between Beta-Secretase and Amyloid Precursor Protein by Park, Jinsu, Madan, Meenu, Chigurupati, Srinivasulu, Baek, Seung Hyun, Cho, Yoonsuk, Mughal, Mohamed R, Yu, Amin, Chan, Sic L, Pattisapu, Jogi V, Mattson, Mark P, Jo, Dong-Gyu

“…Abstract The accumulation of amyloid-β (Aβ) is a characteristic event in the pathogenesis of Alzheimer’s disease (AD). Aquaporin 1 (AQP1) is a membrane water…”
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Abstract B60: Targeting the polyamine addiction of pancreatic cancers: Combination therapies and biomarkers by Phanstiel, Otto, Madan, Meenu, Patel, Arjun, Skruber, Kristen, Altomare, Deborah A.

“…Abstract This project developed a combination therapy which inhibits both polyamine transport and biosynthesis in an effort to target the polyamine addiction…”
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Reduced skeletal muscle secreted frizzled‐related protein 3 is associated with inflammation and insulin resistance by Pachori, Alok S., Madan, Meenu, Nunez Lopez, Yury O., Yi, Fanchao, Meyer, Christian, Seyhan, Attila A.

“…Objective To investigate the role of secreted frizzled‐related protein 3 (Sfrp3) in insulin sensitivity (ISi) and β‐cell function in humans across a spectrum…”
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ATP13A3 and caveolin-1 as potential biomarkers for difluoromethylornithine-based therapies in pancreatic cancers by Madan, Meenu, Patel, Arjun, Skruber, Kristen, Geerts, Dirk, Altomare, Deborah A, Iv, Otto Phanstiel

“…The purpose of this paper was to better understand the role of polyamine transport in pancreatic cancers.This paper identifies potential biomarkers for…”
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Effect of acetazolamide on aquaporin-1 and fluid flow in cultured choroid plexus by Ameli, Pouya A, Madan, Meenu, Chigurupati, Srinivasulu, Yu, Amin, Chan, Sic L, Pattisapu, Jogi V

“…Acetazolamide (AZA), used in treatment of early or infantile hydrocephalus, is effective in some cases, while its effect on the choroid plexus (CP) remains…”
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Expression of aquaporins in a transgenic mouse model of Alzheimer's disease by Chan, Sic L, Madan, Meenu, Chigurupati, Srinu, Pattisapu, Jogi V

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Acetazolamide affects Aquaporin 1 expression of cultured choroid plexus cells by Pattisapu, Jogi V, Ameli, Pouya, Madan, Meenu, Yu, Amin, Chigurupathi, Srinu, Chan, Sic L

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The altered expression of aquaporin 1 and 4 in choroid plexus of congenital hydrocephalus by Paul, Leena, Madan, Meenu, Rammling, Matthias, Behnam, Babak, Pattisapu, Jogi V

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Evidence for altered Numb isoform levels in Alzheimer's disease patients and a triple transgenic mouse model by Chigurupati, Srinivasulu, Madan, Meenu, Okun, Eitan, Wei, Zelan, Pattisapu, Jogi V, Mughal, Mohamed R, Mattson, Mark P, Chan, Sic L

“…The cell fate determinant Numb exists in four alternatively spliced variants that differ in the length of their PTB (phosphotyrosine-binding domain, either…”
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Structural prediction and analysis of VIH-related peptides from selected crustacean species by Nagaraju, Ganji Purna Chandra, Kumari, Nunna Siva, Prasad, Ganji Lakshmi Vara, Rajitha, Balney, Meenu, Madan, Rao, Manam Sreenivasa, Naik, Bannoth Reddya

“…The tentative elucidation of the 3D-structure of vitellogenesis inhibiting hormone (VIH) peptides is conversely underprivileged by difficulties in gaining…”
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