Search Results - "Macpherson, Neil"
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Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes
Published in Genome research (01-02-2017)“…Transcriptional enhancers are critical for maintaining cell-type-specific gene expression and driving cell fate changes during development. Highly transcribed…”
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A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential
Published in Genes & development (15-12-2014)“…The Sox2 transcription factor must be robustly transcribed in embryonic stem (ES) cells to maintain pluripotency. Two gene-proximal enhancers, Sox2 regulatory…”
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3
Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus
Published in Genes & development (01-06-2022)“…How distal regulatory elements control gene transcription and chromatin topology is not clearly defined, yet these processes are closely linked in lineage…”
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4
Arabidopsis Annexin1 Mediates the Radical-Activated Plasma Membrane Ca²⁺- and K⁺-Permeable Conductance in Root Cells
Published in The Plant cell (01-04-2012)“…Plant cell growth and stress signaling require Ca²⁺ influx through plasma membrane transport proteins that are regulated by reactive oxygen species. In root…”
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5
Annexins: multifunctional components of growth and adaptation
Published in Journal of Experimental Botany (01-02-2008)“…Plant annexins are ubiquitous, soluble proteins capable of Ca²⁺-dependent and Ca²⁺-independent binding to endomembranes and the plasma membrane. Some members…”
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Journal Article Book Review -
6
Correction: The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium
Published in eLife (19-05-2022)Get full text
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The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium
Published in eLife (23-03-2021)“…In emerging epithelial tissues, cells undergo dramatic rearrangements to promote tissue shape changes. Dividing cells remain interconnected via transient…”
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8
Chromatin Dynamics in Lineage Commitment and Cellular Reprogramming
Published in Genes (17-07-2015)“…Dynamic structural properties of chromatin play an essential role in defining cell identity and function. Transcription factors and chromatin modifiers…”
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Journal Article Book Review -
9
Randomised controlled trial of ultrasonography in diagnosis of acute appendicitis, incorporating the Alvarado score
Published in BMJ (14-10-2000)“…Abstract Objectives: To determine whether diagnosis by graded compression ultrasonography improves clinical outcomes for patients with suspected appendicitis…”
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10
Copper toxicity in a New Zealand dairy herd
Published in Irish Veterinary Journal (23-09-2014)“…Chronic copper toxicity was diagnosed in a Jersey herd in the Waikato region of New Zealand following an investigation into the deaths of six cattle from a…”
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11
Effect of different suture techniques on tension dispersion in cutaneous wounds: A pilot study
Published in Australasian journal of dermatology (01-11-2010)“…ABSTRACT Background/Objectives: Wound tension plays an integral role in both wound healing and cosmesis. The use of W‐plasty has been shown to evenly…”
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12
Zea mays Annexins Modulate Cytosolic Free Ca²⁺ and Generate a Ca²⁺-Permeable Conductance
Published in The Plant cell (01-02-2009)“…Regulation of reactive oxygen species and cytosolic free calcium ([Ca²⁺]cyt) is central to plant function. Annexins are small proteins capable of…”
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13
Nuclear organization of RNA polymerase II transcription
Published in Biochemistry and cell biology (01-02-2013)“…Transcription occurs at distinct nuclear compartments termed transcription factories that are specialized for transcription by 1 of the 3 polymerase complexes…”
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14
Effect of inflammation on positive margins of basal cell carcinomas
Published in Australasian journal of dermatology (01-05-2010)“…ABSTRACT Background/Objectives: The use of preparations such as imiquimod in the treatment of basal cell carcinoma is well accepted. Imiquimod induces…”
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15
Randomised controlled trial of ultrasonography in diagnosis of acute appendicitis, incorporating the Alvarado score
Published in BMJ. British medical journal (International ed.) (14-10-2000)“…OBJECTIVES: To determine whether diagnosis by graded compression ultrasonography improves clinical outcomes for patients with suspected appendicitis. DESIGN: A…”
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16
NADPH oxidase involvement in cellular integrity
Published in Planta (01-05-2008)“…NADPH oxidase activity is involved in plant adaptation and development. The reactive oxygen species sourced by NADPH oxidase activity may contribute to wall…”
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Arabidopsis Annexin1 Mediates the Radical-Activated Plasma Membrane Ca 2+ - and K + -Permeable Conductance in Root Cells
Published in The Plant cell (01-04-2012)Get full text
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Arabidopsis Annexin1 Mediates the Radical-Activated Plasma Membrane Ca^sup 2+^- and K^sup +^-Permeable Conductance in Root Cells(W)
Published in The Plant cell (01-04-2012)“…Plant cell growth and stress signaling require Ca² influx through plasma membrane transport proteins that are regulated by reactive oxygen species. In root…”
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19
Potassium transport at the plasma membrane of the food spoilage yeastZygosaccharomyces bailii
Published in Yeast (Chichester, England) (15-01-2005)Get full text
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Plasma membrane H+ and K+ transporters are involved in the weak-acid preservative response of disparate food spoilage yeasts
Published in Microbiology (Society for General Microbiology) (01-06-2005)“…1 Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EA, UK 2 Department of Agricultural Sciences, University of Tasmania,…”
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