Search Results - "Macpherson, David"

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition by Augert, Arnaud, Eastwood, Emily, Ibrahim, Ali H, Wu, Nan, Grunblatt, Eli, Basom, Ryan, Liggitt, Denny, Eaton, Keith D, Martins, Renato, Poirier, John T, Rudin, Charles M, Milletti, Francesca, Cheng, Wei-Yi, Mack, Fiona, MacPherson, David

“…Small cell lung cancer (SCLC) is a recalcitrant, aggressive neuroendocrine-type cancer for which little change to first-line standard-of-care treatment has…”
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Lung Cancer Subtypes Generate Unique Immune Responses by Busch, Stephanie E, Hanke, Mark L, Kargl, Julia, Metz, Heather E, MacPherson, David, Houghton, A McGarry

“…Lung cancer, the leading cause of cancer-related deaths worldwide, is a heterogeneous disease comprising multiple histologic subtypes that harbor disparate…”
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THE AFFORDABLE CARE ACT AND THE GROWTH OF INVOLUNTARY PART-TIME EMPLOYMENT by EVEN, WILLIAM E., MACPHERSON, DAVID A.

“…This study tests whether the employer mandate under the Affordable Care Act (ACA) increased involuntary part-time (IPT) employment. Using data from the Current…”
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Five decades of CPS wages, methods, and union‐nonunion wage gaps at Unionstats.com by Macpherson, David A., Hirsch, Barry T.

“…Unionstats.com provides annual measures of union, nonunion, and overall wages, beginning in 1973, compiled from the U.S. Current Population Surveys…”
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Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance) by Augert, Arnaud, Zhang, Qing, Bates, Breanna, Cui, Min, Wang, Xiaofei, Wildey, Gary, Dowlati, Afshin, MacPherson, David

“…SCLC is a lethal neuroendocrine tumor type that is highly prone to metastasis. There is an urgency to understand the mutated genes that promote SCLC, as there…”
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PTEN is a potent suppressor of small cell lung cancer by Cui, Min, Augert, Arnaud, Rongione, Michael, Conkrite, Karina, Parazzoli, Susan, Nikitin, Alexander Yu, Ingolia, Nicholas, MacPherson, David

“…Small cell lung carcinoma (SCLC) is a highly metastatic tumor type with neuroendocrine features and a dismal prognosis. PTEN mutations and PIK3CA activating…”
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Small cell lung cancer: New insights into origins by MacPherson, David

“…Comment on: Park K, et al. Cell Cycle 2011; 10:2806-15…”
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A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA by Doebley, Anna-Lisa, Ko, Minjeong, Liao, Hanna, Cruikshank, A. Eden, Santos, Katheryn, Kikawa, Caroline, Hiatt, Joseph B., Patton, Robert D., De Sarkar, Navonil, Collier, Katharine A., Hoge, Anna C. H., Chen, Katharine, Zimmer, Anat, Weber, Zachary T., Adil, Mohamed, Reichel, Jonathan B., Polak, Paz, Adalsteinsson, Viktor A., Nelson, Peter S., MacPherson, David, Parsons, Heather A., Stover, Daniel G., Ha, Gavin

“…Cell-free DNA (cfDNA) has the potential to inform tumor subtype classification and help guide clinical precision oncology. Here we develop Griffin, a framework…”
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Insights from mouse models into human retinoblastoma by Macpherson, David

“…Novel murine models of retinoblastoma based on Rb gene deletion in concert with inactivation of Rb family members have recently been developed. These new Rb…”
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The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung by Gazdar, Adi F, Savage, Trisha K, Johnson, Jane E, Berns, Anton, Sage, Julien, Linnoila, R Ilona, MacPherson, David, McFadden, David G, Farago, Anna, Jacks, Tyler, Travis, William D, Brambilla, Elisabeth

“…Because small-cell lung carcinomas (SCLC) are seldom resected, human materials for study are limited. Thus, genetically engineered mouse models (GEMMs) for…”
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Active Care Management Supported by Home Telemonitoring in Veterans With Type 2 Diabetes: The DiaTel randomized controlled trial by Stone, Roslyn A, Rao, R Harsha, Sevick, Mary Ann, Cheng, Chunrong, Hough, Linda J, Macpherson, David S, Franko, Carol M, Anglin, Rebecca A, Obrosky, D Scott, DeRubertis, Frederick R

“…We compared the short-term efficacy of home telemonitoring coupled with active medication management by a nurse practitioner with a monthly care coordination…”
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Neuroendocrine lineage commitment of small cell lung cancers can be leveraged into p53-independent non-cytotoxic therapy by Biswas, Sudipta, Kang, Kai, Ng, Kwok Peng, Radivoyevitch, Tomas, Schalper, Kurt, Zhang, Hua, Lindner, Daniel J., Thomas, Anish, MacPherson, David, Gastman, Brian, Schrump, David S., Wong, Kwok-Kin, Velcheti, Vamsidhar, Saunthararajah, Yogen

“…Small cell lung cancers (SCLCs) rapidly resist cytotoxic chemotherapy and immune checkpoint inhibitor (ICI) treatments. New, non-cross-resistant therapies are…”
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Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness by Mathsyaraja, Haritha, Catchpole, Jonathen, Freie, Brian, Eastwood, Emily, Babaeva, Ekaterina, Geuenich, Michael, Cheng, Pei Feng, Ayers, Jessica, Yu, Ming, Wu, Nan, Moorthi, Sitapriya, Poudel, Kumud R, Koehne, Amanda, Grady, William, Houghton, A McGarry, Berger, Alice H, Shiio, Yuzuru, MacPherson, David, Eisenman, Robert N

“…MGA, a transcription factor and member of the MYC network, is mutated or deleted in a broad spectrum of malignancies. As a critical test of a tumor suppressive…”
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Where Does the Minimum Wage Bite Hardest in California? by Even, William E., Macpherson, David A.

“…This study uses employment data on California county-industry pairs (CIPs) between 1990 and 2016 to test whether minimum wage increases caused employment…”
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Author Correction: A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA by Doebley, Anna-Lisa, Ko, Minjeong, Liao, Hanna, Cruikshank, A. Eden, Santos, Katheryn, Kikawa, Caroline, Hiatt, Joseph B., Patton, Robert D., De Sarkar, Navonil, Collier, Katharine A., Hoge, Anna C. H., Chen, Katharine, Zimmer, Anat, Weber, Zachary T., Adil, Mohamed, Reichel, Jonathan B., Polak, Paz, Adalsteinsson, Viktor A., Nelson, Peter S., MacPherson, David, Parsons, Heather A., Stover, Daniel G., Ha, Gavin

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Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia by Witty, David R, Alvaro, Giuseppe, Derjean, Dominique, Giblin, Gerard M. P, Gunn, Kevin, Large, Charles, Macpherson, David T, Morisset, Valerie, Owen, Davina, Palmer, Joanne, Rugiero, Francois, Tate, Simon, Hinckley, Christopher A, Naik, Himanshu

“…Drugs that block voltage-gated sodium channels (NaVs) have utility in treating conditions including pain, epilepsy, and cardiac arrhythmias and as anesthetics…”
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Cooperation between Rb and Arf in suppressing mouse retinoblastoma by Conkrite, Karina, Sundby, Maggie, Mu, David, Mukai, Shizuo, MacPherson, David

“…Retinoblastoma is a pediatric cancer that has served as a paradigm for tumor suppressor gene function. Retinoblastoma is initiated by RB gene mutations, but…”
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The Gender Wage Gap and the Fair Calculations Act by Even, William E., Macpherson, David A.

“…If enacted into law, the Fair Calculations Act would require forensic economists to ignore an injured party's gender when forecasting the loss in future…”
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Cell type-specific effects of Rb deletion in the murine retina by MacPherson, David, Sage, Julien, Kim, Teresa, Ho, Dennis, McLaughlin, Margaret E, Jacks, Tyler

“…Certain cells of the human retina are extremely sensitive to loss of function of the retinoblastoma tumor suppressor gene RB. Retinoblastomas develop early in…”
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Deferred compensation vs. efficiency wages: An experimental test of effort provision and self-selection by Macpherson, David A., Prasad, Kislaya, Salmon, Timothy C.

“…•We compare efficiency wages with deferred compensation.•We test predictions on effort provision and preference between wage structures.•Theoretical…”
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