Search Results - "Macon, Lara"
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MEK1/2 Inhibition Promotes Macrophage Reparative Properties
Published in The Journal of immunology (1950) (15-01-2017)“…Macrophages have important functional roles in regulating the timely promotion and resolution of inflammation. Although many of the intracellular signaling…”
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sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country
Published in BMC medicine (01-07-2020)“…Few studies of biomarkers as predictors of outcome in infection have been performed in tropical, low- and middle-income countries where the burden of sepsis is…”
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Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-α release in Burkholderia thailandensis infection in vitro
Published in PLoS neglected tropical diseases (01-08-2020)“…Melioidosis is an often-severe tropical infection caused by Burkholderia pseudomallei (Bp) with high associated morbidity and mortality. Burkholderia…”
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Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
Published in PLoS neglected tropical diseases (01-05-2019)“…Toll-like receptors (TLRs) are sentinel receptors of the innate immune system. TLR4 detects bacterial lipopolysaccharide (LPS) and TLR5 detects bacterial…”
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IL-1R2-based biomarker models predict melioidosis mortality independent of clinical data
Published in Frontiers in medicine (29-06-2023)“…Melioidosis is an often-fatal tropical infectious disease caused by the Gram-negative bacillus , but few studies have identified promising biomarker candidates…”
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Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis
Published in Emerging microbes & infections (01-01-2019)“…Melioidosis, an infectious disease caused by the bacterium Burkholderia pseudomallei, is a common cause of sepsis in Southeast Asia. We investigated whether…”
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PSX-8 Genetic characterization of Raramuri Criollo cattle introduced into the Southwestern United States
Published in Journal of animal science (14-09-2024)“…Abstract The Raramuri Criollo (RC) is a heritage cattle biotype preserved with minimal selection or crossbreeding for nearly five centuries by the Tarahumara…”
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PSII-20 Virtual Fencing of Rangeland Cows During Late Lactation and Following Weaning
Published in Journal of animal science (06-11-2023)“…Abstract Virtual fencing is a promising alternative to contain livestock dispersal without using physical barriers. This technology uses smart-wearable collars…”
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Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to Burkholderia pseudomallei , a lung-tropic pathogen
Published in Infection and immunity (07-05-2024)“…Melioidosis is an emerging tropical infection caused by inhalation, inoculation, or ingestion of the flagellated, facultatively intracellular pathogen . The…”
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PSXII-1 Comparative analysis of the training response of Raramuri Criollo and Angus Cattle to virtual fencing
Published in Journal of animal science (14-09-2024)“…Abstract Virtual fencing (VF) collars rely on GPS tracking and audio warning-electric cueing to exclude or contain livestock inside geofencing zones…”
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PSIV-23 Activity Classification of Grazing Cows on Desert Rangeland in the Southwestern United States
Published in Journal of animal science (06-11-2023)“…Abstract Monitoring cattle on rangelands is a daunting task that can be improved by using wearable sensors that are capable of transmitting motion and position…”
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PSIV-22 Detection of Parturition of Rangeland Beef Cattle Using Gps and Accelerometer Data
Published in Journal of animal science (06-11-2023)“…Abstract Detection of parturition of rangeland cows remotely may be possible using low cost LoRa WAN monitoring systems that are capable of logging and…”
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The LTAR Grazing Land Common Experiment at the Jornada Experimental Range: Old genetics, new precision technologies, and adaptive value chains
Published in Journal of environmental quality (01-11-2024)“…Rangelands and the supply chains connected to them are central to the agrifood systems of the Southwestern United States. Local ranchers are simultaneously…”
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A macrophage-targeted platform for extending drug dosing with polymer prodrugs for pulmonary infection prophylaxis
Published in Journal of controlled release (10-02-2021)“…Pulmonary melioidosis is a bacterial disease with high morbidity and a mortality rate that can be as high as 40% in resource-poor regions of South Asia. This…”
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A 2-Biomarker Model Augments Clinical Prediction of Mortality in Melioidosis
Published in Clinical infectious diseases (01-03-2021)“…Abstract Background Melioidosis, infection caused by Burkholderia pseudomallei, is a common cause of sepsis with high associated mortality in Southeast Asia…”
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Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-[alpha] release in Burkholderia thailandensis infection in vitro
Published in PLoS neglected tropical diseases (07-08-2020)“…Melioidosis is an often-severe tropical infection caused by Burkholderia pseudomallei (Bp) with high associated morbidity and mortality. Burkholderia…”
Get full text
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MEK1/2 Inhibition Promotes Macrophage Reparative Properties1
Published in The Journal of immunology (1950) (21-12-2016)“…Macrophages have important functional roles in regulating the timely promotion and resolution of inflammation. While many of the intracellular signaling…”
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Immunomodulatory Effects of Lactoferrin during Burkholderia thailandensis Infection
Published in Open forum infectious diseases (01-10-2017)Get full text
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Dysregulated immunologic landscape of the early host response in melioidosis
Published in JCI insight (20-08-2024)“…Melioidosis, a neglected tropical infection caused by Burkholderia pseudomallei, commonly presents as pneumonia or sepsis with mortality rates up to 50%…”
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