Search Results - "Macklis, Roger"

Radium-223 in the Treatment of Osteoblastic Metastases: A Critical Clinical Review by Humm, John L., PhD, Sartor, Oliver, MD, Parker, Chris, MD, Bruland, Oyvind S., MD, PhD, Macklis, Roger, MD

“…The element radium (Ra) was discovered by the Curies in 1898 and within a decade was in broad scientific testing for the management of several forms of cancer…”
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Surface levels of CD20 determine anti-CD20 antibodies mediated cell death in vitro by Singh, Vijay, Gupta, Damodar, Arora, Rajesh, Tripathi, Rajendra Prashad, Almasan, Alexandru, Macklis, Roger M

“…The sensitivity of human Burkitt's lymphoma cells to rituximab (Rtx) and tositumomab (Tst) was assessed on cells expressing different levels of CD20 on…”
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Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation by Komarova, Elena A, Gudkov, Andrei V, Strom, Evguenia, Sathe, Swati, Komarov, Pavel G, Chernova, Olga B, Pavlovska, Ivanda, Shyshynova, Inna, Bosykh, Dmitry A, Burdelya, Lyudmila G, Macklis, Roger M, Skaliter, Rami

“…p53-dependent apoptosis contributes to the side effects of cancer treatment, and genetic or pharmacological inhibition of p53 function can increase normal…”
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The Evolving Role of Radiation Therapy in the Management of Malignant Melanoma by Khan, Niloufer, B.A, Khan, Mohammad K., M.D., Ph.D, Almasan, Alex, Ph.D, Singh, Arun D., M.D, Macklis, Roger, M.D

“…The incidence of melanoma is rising in the United States, leading to an estimated 68,720 new diagnoses and 8,650 deaths annually. The natural history involves…”
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Treatment of Anaplastic Histology Wilms' Tumor: Results From the Fifth National Wilms' Tumor Study by DOME, Jeffrey S, COTTON, Cecilia A, HAASE, Gerald M, COPPES, Max J, COCCIA, Peter, KLETZEL, Morris, WEETMAN, Robert M, DONALDSON, Milton, MACKLIS, Roger M, GREEN, Daniel M, PERLMAN, Elizabeth J, BRESLOW, Norman E, KALAPURAKAL, John A, RITCHEY, Michael L, GRUNDY, Paul E, MALOGOLOWKIN, Marcio, BECKWITH, J. Bruce, SHAMBERGER, Robert C

“…An objective of the fifth National Wilms' Tumor Study (NWTS-5) was to evaluate the efficacy of treatment regimens for anaplastic histology Wilms' tumor (AH)…”
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Impact of Postmastectomy Radiation on Locoregional Recurrence in Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated With Modern Systemic Therapy by Tendulkar, Rahul D., MD, Rehman, Sana, BS, Shukla, Monica E., MD, Reddy, Chandana A., MS, Moore, Halle, MD, Budd, G. Thomas, MD, Dietz, Jill, MD, Crowe, Joseph P., MD, Macklis, Roger, MD

“…Purpose Postmastectomy radiation therapy (PMRT) remains controversial for patients with 1-3 positive lymph nodes (LN+). Methods and Materials We conducted a…”
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Loss of Heterozygosity for Chromosomes 1p and 16q Is an Adverse Prognostic Factor in Favorable-Histology Wilms Tumor: A Report From the National Wilms Tumor Study Group by Grundy, Paul E, Breslow, Norman E, Li, Sierra, Perlman, Elizabeth, Beckwith, J Bruce, Ritchey, Michael L, Shamberger, Robert C, Haase, Gerald M, D'Angio, Giulio J, Donaldson, Milton, Coppes, Max J, Malogolowkin, Marcio, Shearer, Patricia, Thomas, Patrick R M, Macklis, Roger, Tomlinson, Gail, Huff, Vicki, Green, Daniel M

“…To determine if tumor-specific loss of heterozygosity (LOH) for chromosomes 1p or 16q is associated with a poorer prognosis for children with…”
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Review of image-guided radiation therapy by Jaffray, David, Kupelian, Patrick, Djemil, Toufik, Macklis, Roger M

“…Image-guided radiation therapy represents a new paradigm in the field of high-precision radiation medicine. A synthesis of recent technological advances in…”
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Regulation of CD20 expression by radiation-induced changes in intracellular redox status by Gupta, Damodar, Crosby, Meredith E., Almasan, Alexandru, Macklis, Roger M.

“…Increasing the levels of CD20 expression in cells that harbor low CD20 levels may enhance their responsiveness to CD20-specific antibody therapies. Here, we…”
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The History of Oncology by Macklis, Roger M., M.D

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Radioimmunotherapy for non-Hodgkin's lymphoma: a review for radiation oncologists by Macklis, Roger M, Pohlman, Brad

“…The aim of this study was to review advances in radioimmunotherapy (RIT) for non-Hodgkin's lymphoma (NHL) and to discuss the role of the radiation oncologist…”
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Radioimmunotherapy as a Therapeutic Option for Non-Hodgkin’s Lymphoma by Macklis, Roger M., MD

“…Radioimmunotherapy (RIT) represents a relatively new antibody-based radiopharmaceutical treatment for patients with various kinds of tumors. Although the field…”
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Plaque Brachytherapy for Uveal Melanoma: A Vision Prognostication Model by Khan, Niloufer, BA, Khan, Mohammad K., MD, PhD, Bena, James, MS, Macklis, Roger, MD, Singh, Arun D., MD

“…Purpose To generate a vision prognostication model after plaque brachytherapy for uveal melanoma. Methods and Materials All patients with primary single…”
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Review of clinical radioimmunotherapy by Pohlman, Brad, Sweetenham, John, Macklis, Roger M

“…Radioimmunotherapy involves a form of biologically targeted radiopharmaceutical treatment in which a radioactive isotope (typically a short-range, high-energy…”
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'Vitamin R' and its younger siblings by Macklis, Roger M

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Iodine-131 tositumomab (Bexxar) in a radiation oncology environment by Macklis, Roger M

“…Iodine-131 (I-131) tositumomab (Bexxar; GlaxoSmithKline, Research Triangle Park, NC) is one of two recently approved radiolabeled antibodies directed against…”
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Convergence technology in cancer medicine by Macklis, Roger M, Sharma, Nidhi

“…The field of convergence technology may be defined as an area of technologic innovation in which multiple devices or functionalities are combined within a…”
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Dosimetric Benefit of a New Ophthalmic Radiation Plaque by Marwaha, Gaurav, MD, Wilkinson, Allan, PhD, Bena, James, MS, Macklis, Roger, MD, Singh, Arun D., MD

“…Purpose To determine whether the computed dosimetry of a new ophthalmic plaque, EP917, when compared with the standard Collaborative Ocular Melanoma Study…”
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Synergistic cytotoxic effects of zoledronic acid and radiation in human prostate cancer and myeloma cell lines by Algur, Ece, Macklis, Roger M, Häfeli, Urs O

“…The clinical use of the potent bisphosphonate zoledronic acid has increased recently, especially for the treatment of bone metastases. Synergistic effects with…”
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How and why does radioimmunotherapy work? by Macklis, Roger M

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