Search Results - "Mackinnon, S. E."

Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women by Mackinnon, E. S., Rao, A. V., Josse, R. G., Rao, L. G.

“…Summary To date, no intervention studies have been published demonstrating the effect of the antioxidant lycopene on bone. Postmenopausal women supplemented…”
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Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women by RAO, L. G, MACKINNON, E. S, JOSSE, R. G, MURRAY, T. M, STRAUSS, A, RAO, A. V

“…Oxidative stress induced by reactive oxygen species (ROS) is associated with the risk of osteoporosis, and can be reduced by certain dietary antioxidants…”
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Dietary restriction of lycopene for a period of one month resulted in significantly increased biomarkers of oxidative stress and bone resorption in postmenopausal women by Mackinnon, E. S., venket Rao, A., Rao, L. G.

“…Background and Objectives Lycopene is a carotenoid commonly found in tomatoes and tomato products which acts as an antioxidant to decrease oxidative stress and…”
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Geldanamycin accelerated peripheral nerve regeneration in comparison to FK-506 in vivo by Sun, H.H, Saheb-Al-Zamani, M, Yan, Y, Hunter, D.A, Mackinnon, S.E, Johnson, P.J

“…Highlights ► Geldanamycin accelerates peripheral nerve regeneration in vivo. ► Geldanamycin treatment is less toxic than treatment with FK-506. ► FK-506 likely…”
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Clinical Outcome following Nerve Allograft Transplantation by Mackinnon, Susan E, Doolabh, Vaishali B, Novak, Christine B, Trulock, Elbert P

“…The clinical outcome of seven patients who underwent reconstruction of long upper- and lower-extremity peripheral nerve gaps with interposition peripheral…”
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Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat by Bain, J R, Mackinnon, S E, Hunter, D A

“…Quantification of peripheral nerve regeneration in animal studies of nerve injury and repair by histologic, morphologic, and electrophysiologic parameters has…”
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FK506 promotes functional recovery in crushed rat sciatic nerve by Lee, Michelle, Doolabh, Vaishali B., Mackinnon, Susan E., Jost, Sarah

“…In this study we examine whether the systemic administration of FK506 or Cyclosporin A (CsA) expedited functional recovery following an axonotmetic nerve…”
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FK506 Accelerates Functional Recovery following Nerve Grafting in a Rat Model by Doolabh, Vaishali B, Mackinnon, Susan E

“…The sometimes dramatic and permanent functional deficits that result from severe peripheral nerve injuries provide compelling incentives to identify exogenous…”
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Cold preserved nerve allografts: Changes in basement membrane, viability, immunogenicity, and regeneration by Evans, Peter J., Mackinnon, Susan E., Levi, Allan D.O., Wade, Judith A., Hunter, Daniel A., Nakao, Yasushi, Midha, Rajiv

“…Rat sciatic nerve graft segments were harvested and pretreated by either placement in the University of Wisconsin Cold Storage Solution at 5°C and storage from…”
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End-to-Side Neurorrhaphy and Lateral Axonal Sprouting in a Long Graft Rat Model by Goheen-Robillard, B., Myckatyn, T. M., Mackinnon, S. E., Hunter, D. A.

“…Objective/Hypothesis Controversy exists regarding collateral axonal sprouting across an end‐to‐side neurorrhaphy to provide functional motor reinnervation of a…”
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Costimulation Blockade of CD40 and CD28 Pathways in Limb Transplantation by Tung, T.H.H, Mackinnon, S.E, Mohanakumar, T

“…Abstract Costimulation blockade remains a promising experimental regimen for the induction of transplantation tolerance. The simultaneous blockade of both the…”
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Nerve transfers. New options for reconstruction following nerve injury by Mackinnon, S E, Novak, C B

“…Surgical reconstruction of proximal level nerve repair or long nerve grafts have provided less than optimal results, presenting the opportunity for…”
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Secondary Carpal Tunnel Surgery by Tung, Thomas H. H, Mackinnon, Susan E

“…A small but significant group of patients with carpal tunnel syndrome “fail” primary carpal tunnel release and require secondary surgery. The persistence or…”
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The effect of duration of muscle denervation on functional recovery in the rat model by Kobayashi, Jun, Mackinnon, Susan E., Watanabe, Osamu, Ball, Douglas J., Ming Gu, Xiao, Hunter, Daniel A., Kuzon Jr, William M.

“…The effect of long‐term denervation on neuromuscular recovery was studied in a rat hind limb model. The posterior tibial nerve was transected and repaired…”
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Walking track analysis: a long-term assessment of peripheral nerve recovery by Hare, G M, Evans, P J, Mackinnon, S E, Best, T J, Bain, J R, Szalai, J P, Hunter, D A

“…Functional recovery following sciatic, tibial, and peroneal nerve injury was assessed over a 1-year period using walking track analysis in the rat. Internal…”
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Quality of life and functional outcome following brachial plexus injury by Choi, P D, Novak, C B, Mackinnon, S E, Kline, D G

“…Thirty-two patients (3 women, 29 men) participated in a mailed questionnaire survey to evaluate long-term subjective, employment, and functional outcome…”
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Flexor digitorum superficialis nerve transfer to restore pronation: Two case reports and anatomic study by Tung, Thomas H.H., Mackinnon, Susan E.

“…Loss of pronation affects most activities of daily living. We report 2 cases of traumatic loss of pronator teres function and successful reconstruction by…”
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Lack of association between outcome measures of nerve regeneration by Munro, Catherine A., Szalai, John P., Mackinnon, Susan E., Midha, Rajiv

“…Studies of nerve regeneration in rodents utilize at least one of three classes of outcome measures: electrophysiology, morphometry, and functional tests. The…”
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Clinical nerve reconstruction with a bioabsorbable polyglycolic acid tube by Mackinnon, S E, Dellon, A L

“…Microneurosurgical techniques to reconstruct nerve gaps with nerve grafts frequently fail to achieve excellent functional results and create donor-site…”
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Nerve transfers in the upper extremity by Nath, R K, Mackinnon, S E

“…Restoration of extremity function following nerve injury is often unpredictable. Nerve transfers in the upper extremity are important techniques in the…”
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