Search Results - "Mackinnon, A. Craig"

Correction: Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells by Mon, Aye M, Craig MacKinnon, Jr, A, Traktman, Paula

“…[This corrects the article DOI: 10.1371/journal.pone.0203397.]…”
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Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells by Mon, Aye M, MacKinnon, Jr, A Craig, Traktman, Paula

“…Vaccinia-related kinase 1 (VRK1) is a pro-proliferative nuclear kinase. Mice engrafted with VRK1-depleted MDA-MB-231 breast cancer cells have been shown to…”
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Molecular pathology as basis for timely cancer diagnosis and therapy by Mackinnon, A. Craig, Chandrashekar, Darshan Shimoga, Suster, David I.

“…Precision and personalized therapeutics have witnessed significant advancements in technology, revolutionizing the capabilities of laboratories to generate…”
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Atypical thymomas with squamoid and spindle cell features: clinicopathologic, immunohistochemical and molecular genetic study of 120 cases with long-term follow-up by Suster, David I., Craig Mackinnon, A., DiStasio, Marcello, Basu, Malay Kumar, Pihan, German, Suster, Saul

“…Thymomas are rare tumors characterized by a broad range of morphologic appearances that can sometimes give rise to difficulties for classification. We have…”
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Myxoinflammatory fibroblastic sarcoma: an immunohistochemical and molecular genetic study of 73 cases by Suster, David, Michal, Michael, Huang, Huiya, Ronen, Shira, Springborn, Stephanie, Debiec-Rychter, Maria, Billings, Steven D., Goldblum, John R., Rubin, Brian P., Michal, Michal, Suster, Saul, Mackinnon, A. Craig

“…Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare, low-grade soft tissue neoplasm preferentially arising in the extremities of young to middle-aged adults…”
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Granulomatous and lymphocytic interstitial lung disease: a spectrum of pulmonary histopathologic lesions in common variable immunodeficiency—histologic and immunohistochemical analyses of 16 cases by Rao, Nagarjun, MD, FRCPath, Mackinnon, A. Craig, MD, PhD, Routes, John M., MD

“…Summary Common variable immunodeficiency is a primary immunodeficiency of unknown etiology characterized by low serum immunoglobulin G, a decreased ability to…”
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Expression patterns for Bcl-2, EMA, β-catenin, E-cadherin, PAX8, and MIB1 in thymomas by Suster, David, Miller, James A., Pihan, German, Mackinnon, A. Craig, Suster, Saul

“…The expression of immunohistochemical markers has been extensively investigated in thymomas to assist in the differential diagnosis. We have studied six select…”
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Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death by GANG CHENG, ZIELONKA, Jacek, DRANKA, Brian P, MCALLISTER, Donna, MACKINNON, A. Craig, JOSEPH, Joy, KALYANARAMAN, Balaraman

“…Cancer cells are long known to exhibit increased aerobic glycolysis, but glycolytic inhibition has not offered a viable chemotherapeutic strategy in part…”
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A Phase II Clinical Trial of Molecular Profiled Neoadjuvant Therapy for Localized Pancreatic Ductal Adenocarcinoma by Tsai, Susan, Christians, Kathleen K, George, Ben, Ritch, Paul S, Dua, Kulwinder, Khan, Abdul, Mackinnon, A Craig, Tolat, Parag, Ahmad, Syed A, Hall, William A, Erickson, Beth A, Evans, Douglas B

“…OBJECTIVES:One facet of precision medicine is the use of tumor molecular profiling to guide chemotherapeutic selection. We conducted the first prospective…”
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Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death by Cheng, Gang, Zielonka, Jacek, McAllister, Donna M, Mackinnon, Jr, A Craig, Joseph, Joy, Dwinell, Michael B, Kalyanaraman, Balaraman

“…Recent research has revealed that targeting mitochondrial bioenergetic metabolism is a promising chemotherapeutic strategy. Key to successful implementation of…”
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CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis by Roy, Ishan, Zimmerman, Noah P, Mackinnon, A Craig, Tsai, Susan, Evans, Douglas B, Dwinell, Michael B

“…Pancreatic ductal adenocarcinoma is an unsolved health problem with nearly 75% of patients diagnosed with advanced disease and an overall 5-year survival rate…”
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Paxillin Is a Target for Somatic Mutations in Lung Cancer : Implications for Cell Growth and Invasion by JAGADEESWARAN, Ramasamy, SURAWSKA, Hanna, SCHWARTZ, Stuart, FAORO, Leonardo, WANG, Yi-Ching, GIRARD, Luc, TRETIAKOVA, Maria S, AHMED, Salman, ZUMBA, Osvaldo, SOULII, Lioubov, BINDOKAS, Vytas P, SZETO, Livia L, KRISHNASWAMY, Soundararajan, GORDON, Gavin J, BUENO, Raphael, SUGARBAKER, David, LINGEN, Mark W, SATTLER, Martin, KRAUSZ, Thomas, VIGNESWARAN, Wickii, NATARAJAN, Viswanathan, MINNA, John, VOKES, Everett E, JANAMANCHI, Varalakshmi, FERGUSON, Mark K, HUSAIN, Aliya N, SALGIA, Ravi, MACKINNON, A. Craig, SEIWERT, Tanguy Y, LOGANATHAN, Sivakumar, KANTETI, Rajani, REICHMAN, Trevor, NALLASURA, Vidya

“…Lung cancer is characterized by abnormal cell growth and invasion, and the actin cytoskeleton plays a major role in these processes. The focal adhesion protein…”
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A Single Center's Approach to Discriminating Donor Versus Host Origin of Renal Neoplasia in the Allograft Kidney by Robin, Adam J., M.D, Cohen, Eric P., M.D, Chongkrairatanakul, Tepsiri, M.D, Saad, Ehad, M.D, Mackinnon, A. Craig, M.D., Ph.D

“…Abstract Renal cell carcinoma (RCC) in the allograft of kidney transplant recipient (KTR) patients is rare, and may represent a de-novo process arising from…”
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Non-Small Cell Lung Carcinoma With Clear Cell Features and FGFR3::TACC3 Gene Rearrangement : Clinicopathologic and Next Generation Sequencing Study of 7 Cases by Suster, David, Mackinnon, A Craig, Ronen, Natali, Mejbel, Haider A, Harada, Shuko, Suster, Saul

“…Seven cases of primary lung tumors characterized histologically by clear cell morphology and a distinctive FGFR3::TACC3 gene rearrangement are described. The…”
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Inflammatory Giant Cell Carcinoma of the Lung: Clinicopathologic, Immunohistochemical, and Next-generation Sequencing Study of 14 Cases by Suster, David I, Mackinnon, A Craig, Ronen, Natali, Mejbel, Haider A, Harada, Shuko, Michal, Michael, Suster, Saul

“…A distinctive histological variant of poorly differentiated, sarcomatoid, non-small cell lung carcinoma characterized by a discohesive population of giant…”
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Solid Thyroid Follicular Nodules With Longitudinal Nuclear Grooves by Suster, David, Mackinnon, A Craig, Nosé, Vania, Suster, Saul

“…Follicular thyroid nodules can be a source of diagnostic difficulties, particularly when they display atypical features commonly associated with malignancy,…”
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Outcomes of the treatment of head and neck sarcomas in a tertiary referral center by Lindford, Andrew, McIntyre, Benjamin, Marsh, Reginald, MacKinnon, Craig A, Davis, Charles, Tan, Swee T

“…Head and neck sarcomas are a rare and heterogeneous group of tumors that pose management challenges. We report our experience with these tumors. Forty…”
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Non-small cell lung carcinoma with clear cell features: a clinicopathologic, immunohistochemical, and molecular study of 31 cases by Suster, David I., Ronen, Natali, Mejbel, Haider A., Harada, Shuko, Mackinnon, A. Craig, Suster, Saul

“…Non-small cell lung carcinoma with predominantly clear cell features is a rare histologic presentation of lung carcinoma. We have examined 31 cases of lung…”
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Epithelioid osteoblastoma. Clinicopathologic and immunohistochemical study of 17 cases by Suster, David, Mackinnon, A. Craig, Jarzembowski, Jason A., Carrera, Guillermo, Suster, Saul, Klein, Michael J.

“…Seventeen cases of epithelioid osteoblastoma were reviewed. The tumors most commonly arose from the vertebrae (7 cases), followed by the mandible (3), sacrum…”
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Tubulopapillary adrenocortical adenoma in a patient with familial adenomatous polyposis: a morphologic, ultrastructural, and molecular study by Huang, Huiya, Chang, Jason, Rosati, Stefano, Geurts, Jennifer, Mackinnon, A. Craig

“…Patients with familial adenomatous polyposis have a higher incidence for developing adrenal neoplasms, most of which are nonfunctioning with conventional…”
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