Search Results - "Mackie, Thomas R."

Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer by Bredfeldt, Jeremy S, Liu, Yuming, Pehlke, Carolyn A, Conklin, Matthew W, Szulczewski, Joseph M, Inman, David R, Keely, Patricia J, Nowak, Robert D, Mackie, Thomas R, Eliceiri, Kevin W

“…Second-harmonic generation (SHG) imaging can help reveal interactions between collagen fibers and cancer cells. Quantitative analysis of SHG images of collagen…”
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Whole Brain Radiotherapy With Hippocampal Avoidance and Simultaneously Integrated Brain Metastases Boost: A Planning Study by Gutiérrez, Alonso N., Ph.D, Westerly, David C., M.Sc, Tomé, Wolfgang A., Ph.D, Jaradat, Hazim A., Ph.D, Mackie, Thomas R., Ph.D, Bentzen, Søren M., Ph.D., D.Sc, Khuntia, Deepak, M.D, Mehta, Minesh P., M.D

“…Purpose To evaluate the feasibility of using tomotherapy to deliver whole brain radiotherapy with hippocampal avoidance, hypothesized to reduce the risk of…”
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A Comprehensive Assessment by Tumor Site of Patient Setup Using Daily MVCT Imaging From More Than 3,800 Helical Tomotherapy Treatments by Schubert, Leah K., M.S, Westerly, David C., M.S, Tomé, Wolfgang A., Ph.D, Mehta, Minesh P., M.D, Soisson, Emilie T., M.S, Mackie, Thomas R., Ph.D, Ritter, Mark A., M.D., Ph.D, Khuntia, Deepak, M.D, Harari, Paul M., M.D, Paliwal, Bhudatt R., Ph.D

“…Purpose To assess patient setup corrections based on daily megavoltage CT (MVCT) imaging for four anatomic treatment sites treated on tomotherapy. Method and…”
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Measuring Efficiency of Semi-automated Brain Tumor Segmentation by Simulating User Interaction by Gering, David, Kotrotsou, Aikaterini, Young-Moxon, Brett, Miller, Neal, Avery, Aaron, Kohli, Lisa, Knapp, Haley, Hoffman, Jeffrey, Chylla, Roger, Peitzman, Linda, Mackie, Thomas R

“…Traditionally, radiologists have crudely quantified tumor extent by measuring the longest and shortest dimension by dragging a cursor between opposite boundary…”
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Radiation characteristics of helical tomotherapy by Jeraj, Robert, Mackie, Thomas R., Balog, John, Olivera, Gustavo, Pearson, Dave, Kapatoes, Jeff, Ruchala, Ken, Reckwerdt, Paul

“…Helical tomotherapy is a dedicated intensity modulated radiation therapy (IMRT) system with on-board imaging capability (MVCT) and therefore differs from…”
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Intensity-Modulated Radiotherapy Might Increase Pneumonitis Risk Relative to Three-Dimensional Conformal Radiotherapy in Patients Receiving Combined Chemotherapy and Radiotherapy: A Modeling Study of Dose Dumping by Vogelius, Ivan S., Ph.D, Westerly, David C., Ph.D, Cannon, George M., M.D, Mackie, Thomas R., Ph.D, Mehta, Minesh P., M.D, Sugie, Chikao, M.D, Bentzen, Søren M., Ph.D., D.Sc

“…Purpose To model the possible interaction between cytotoxic chemotherapy and the radiation dose distribution with respect to the risk of radiation pneumonitis…”
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A Dosimetric Comparison of Accelerated Partial Breast Irradiation Techniques: Multicatheter Interstitial Brachytherapy, Three-Dimensional Conformal Radiotherapy, and Supine Versus Prone Helical Tomotherapy by Patel, Rakesh R., M.D, Becker, Stewart J., Ph.D, Das, Rupak K., Ph.D, Mackie, Thomas R., Ph.D

“…Purpose: To compare dosimetrically four different techniques of accelerated partial breast irradiation (APBI) in the same patient. Methods and Materials:…”
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Treatment Planning to Improve Delivery Accuracy and Patient Throughput in Helical Tomotherapy by Westerly, David C., M.Sc, Soisson, Emilie, M.Sc, Chen, Quan, Ph.D, Woch, Katherine, M.Sc, Schubert, Leah, M.Sc, Olivera, Gustavo, Ph.D, Mackie, Thomas R., Ph.D

“…Purpose To investigate delivery quality assurance (DQA) discrepancies observed for a subset of helical tomotherapy patients. Methods and Materials Six…”
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Application of the spirometer in respiratory gated radiotherapy by Zhang, Tiezhi, Keller, Harry, O’Brien, Matthew J., Mackie, Thomas R., Paliwal, Bhudatt

“…The signal from a spirometer is directly correlated with respiratory motion and is ideal for target respiratory motion tracking. However, its susceptibility to…”
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Monte Carlo-based analytical model for small and variable fields delivered by TomoTherapy by Sterpin, Edmond, Hundertmark, Brian T, Mackie, Thomas R, Lu, Weiguo, Olivera, Gustavo H, Vynckier, Stefaan

“…Abstract Background and purpose Extend to very small fields the validity of a Monte Carlo (MC) based model of TomoTherapy called TomoPen for future…”
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Accurate convolution/superposition for multi-resolution dose calculation using cumulative tabulated kernels by Lu, Weiguo, Olivera, Gustavo H, Chen, Ming-Li, Reckwerdt, Paul J, Mackie, Thomas R

“…Convolution/superposition (C/S) is regarded as the standard dose calculation method in most modern radiotherapy treatment planning systems. Different…”
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A phantom model demonstration of tomotherapy dose painting delivery, including managed respiratory motion without motion management by Kissick, Michael W, Mo, Xiaohu, McCall, Keisha C, Schubert, Leah K, Westerly, David C, Mackie, Thomas R

“…The aim of the study was to demonstrate a potential alternative scenario for accurate dose-painting (non-homogeneous planned dose) delivery at 1 cm beam width…”
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Treatment plan optimization incorporating respiratory motion by Zhang, Tiezhi, Jeraj, Robert, Keller, Harry, Lu, Weiguo, Olivera, Gustavo H., McNutt, Todd R., Mackie, Thomas R., Paliwal, Bhudatt

“…Similar to conventional conformal radiotherapy, during lung tomotherapy, a motion margin has to be set for respiratory motion. Consequently, large volume of…”
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Opportunities and challenges to utilization of quantitative imaging: Report of the AAPM practical big data workshop by Mackie, Thomas R., Jackson, Edward F., Giger, Maryellen

“…Background This article is a summary of the quantitative imaging subgroup of the 2017 AAPM Practical Big Data Workshop (PBDW‐2017) on progress and challenges…”
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Fast treatment plan modification with an over-relaxed Cimmino algorithm by Wu, Chuan, Jeraj, Robert, Lu, Weiguo, Mackie, Thomas. R.

“…A method to quickly modify a treatment plan in adaptive radiotherapy was proposed and studied. The method is based on a Cimmino-type algorithm in linear…”
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Breathing-Synchronized Delivery: A Potential Four-Dimensional Tomotherapy Treatment Technique by Zhang, Tiezhi, Ph.D, Lu, Weiguo, Ph.D, Olivera, Gustavo H., Ph.D, Keller, Harry, Ph.D, Jeraj, Robert, Ph.D, Manon, Rafael, M.D, Mehta, Minesh, M.D, Mackie, Thomas R., Ph.D, Paliwal, Bhudatt, Ph.D

“…Purpose: To introduce a four-dimensional (4D) tomotherapy treatment technique with improved motion control and patient tolerance. Methods and Materials:…”
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DOSIMETRIC IMPACT OF DAILY SETUP VARIATIONS DURING TREATMENT OF CANINE NASAL TUMORS USING INTENSITY-MODULATED RADIATION THERAPY by DEVEAU, MICHAEL A, GUTIÉRREZ, ALONSO N, MACKIE, THOMAS R, TOMÉ, WOLFGANG A, FORREST, LISA J

“…Intensity-modulated radiation therapy (IMRT) can be employed to yield precise dose distributions that tightly conform to targets and reduce high doses to…”
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Texture analysis applied to second harmonic generation image data for ovarian cancer classification by Wen, Bruce L, Brewer, Molly A, Nadiarnykh, Oleg, Hocker, James, Singh, Vikas, Mackie, Thomas R, Campagnola, Paul J

“…Remodeling of the extracellular matrix has been implicated in ovarian cancer. To quantitate the remodeling, we implement a form of texture analysis to…”
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Automated quantification of aligned collagen for human breast carcinoma prognosis by Bredfeldt, Jeremy S., Liu, Yuming, Conklin, Matthew W., Keely, Patricia J., Mackie, Thomas R., Eliceiri, Kevin W.

“…Background: Mortality in cancer patients is directly attributable to the ability of cancer cells to metastasize to distant sites from the primary tumor. This…”
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A generalized 2D pencil beam scaling algorithm for proton dose calculation in heterogeneous slab geometries by Westerly, David C., Mo, Xiaohu, Tomé, Wolfgang A., Mackie, Thomas R., DeLuca, Paul M.

“…Purpose: Pencil beam algorithms are commonly used for proton therapy dose calculations.Szymanowski and Oelfke [“Two-dimensional pencil beam scaling: An…”
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