Search Results - "Mackey, Z."

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain by Fujii, Naoaki, Mallari, Jeremy P., Hansell, Elizabeth J., Mackey, Z., Doyle, Patricia, Zhou, Y.M., Gut, Jiri, Rosenthal, Philip J., McKerrow, James H., Guy, R. Kiplin

“…Herein we report the synthesis and evaluation of a series of thiosemicarbazones as potential inhibitors of cysteine proteases relevant to parasitic diseases…”
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Poetic transcription and its possibilities for (re)presentation by Yi, Varaxy, Mackey, Janiece Z.

“…Two women scholars (Khmer and Black) explore how our subjectivities as researchers influence how we understand, give honor to, and (re)present our…”
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Physical and Functional Interaction between DNA Ligase IIIα and Poly(ADP-Ribose) Polymerase 1 in DNA Single-Strand Break Repair by Leppard, John B., Dong, Zhiwan, Mackey, Zachary B., Tomkinson, Alan E.

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An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination by Mackey, Zachary B., Ramos, William, Levin, David S., Walter, Christi A., McCarrey, John R., Tomkinson, Alan E.

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Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination by Chen, Jingwen, Tomkinson, Alan E., Ramos, William, Mackey, Zachary B., Danehower, Sue, Walter, Christi A., Schultz, Roger A., Besterman, Jeffrey M., Husain, Intisar

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DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III by Mackey, Z B, Niedergang, C, Murcia, J M, Leppard, J, Au, K, Chen, J, de Murcia, G, Tomkinson, A E

“…Mammalian DNA ligases are composed of a conserved catalytic domain flanked by unrelated sequences. At the C-terminal end of the catalytic domain, there is a…”
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An easily dissociated 26 S proteasome catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei by Li, Ziyin, Zou, Chun-Bin, Yao, Yi, Hoyt, Martin A, McDonough, Stephen, Mackey, Zachary B, Coffino, Philip, Wang, Ching C

“…The 26 S proteasome, a complex between the 20 S proteasome and 19 S regulatory units, catalyzes ATP-dependent degradation of unfolded and ubiquitinated…”
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Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation by Wang, Y.C., Burkhart, W.A., Mackey, Z.B., Moyer, M.B., Ramos, W, Husain, I, Chen, J, Besterman, J.M., Tomkinson, A.E.

“…Mammalian cells contain three biochemically distinct DNA ligases. In this report we describe the purification of DNA ligase II to homogeneity from bovine liver…”
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Antitrypanosomal Activity of 5‘-Deoxy-5‘-(iodomethylene)adenosine and Related 6-N-Cyclopropyladenosine Analogues by Rapp, Magdalena, Haubrich, Trisha A, Perrault, Jacques, Mackey, Zachary B, McKerrow, James H, Chiang, Peter K, Wnuk, Stanislaw F

“…Treatment of the 6-N-cyclopropyl-2‘,3‘-di-O-isopropylideneadenosine 5‘-aldehyde with sulfone-stabilized phosphonate or fluorophosphonate reagents followed by…”
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Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice by KAMEL, D, MACKEY, Z. B, SJÖBLOM, T, WALTER, C. A, MCCARREY, J. R, UITTO, L, PALOSAARI, H, LÄHDETIE, J, TOMKINSON, A. E, SYVÄOJA, J. E

“…Previous studies on DNA polymerase epsilon indicate that this enzyme is involved in replication of chromosomal DNA. In this study, we examined the expression…”
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Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi by Greenbaum, Doron C, Mackey, Zachary, Hansell, Elizabeth, Doyle, Patricia, Gut, Jiri, Caffrey, Conor R, Lehrman, Julia, Rosenthal, Philip J, McKerrow, James H, Chibale, Kelly

“…We have synthesized a library of thiosemicarbazones and screened them against three parasitic cysteine proteases, cruzain, falcipain-2, and rhodesain, and…”
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Purification and characterization of DNA ligase III from bovine testes. Homology with DNA ligase II and vaccinia DNA ligase by Husain, I, Tomkinson, A E, Burkhart, W A, Moyer, M B, Ramos, W, Mackey, Z B, Besterman, J M, Chen, J

“…Mammalian cell nuclei contain three biochemically distinct DNA ligases. In the present study we have found high levels of DNA ligase I and DNA ligase III…”
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Structure and function of mammalian DNA ligases by Tomkinson, Alan E, Mackey, Zachary B

“…DNA joining events are required for the completion of DNA replication, DNA excision repair and genetic recombination. Five DNA ligase activities, I–V, have…”
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Forsaking Neutrality in Political Science: Making the Case to Intellectually Assassinate by Mackey, Janiece Z

“…The author conducted a self-study of her "American Political Thought" political science course, utilizing anonymous midterm evaluations to unpack the ways…”
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Black Finesse Amidst the Political Science Paradigm: A Race-Grounded Phenomenology by Mackey, Janiece Z

“…In this research, I develop a methodology that I call Race-Grounded Phenomenology (RGP). The scope of this study investigates how Black undergraduate students…”
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Completion of base excision repair by mammalian DNA ligases by Tomkinson, Alan E, Chen, Ling, Dong, Zhiwan, Leppard, John B, Levin, David S, Mackey, Zachary B, Motycka, Teresa A

“…Three mammalian genes encoding DNA ligases—LIG1, LIG3, and LIG4—have been identified. Genetic, biochemical, and cell biology studies indicate that the products…”
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A Cathepsin B-like Protease Is Required for Host Protein Degradation in Trypanosoma brucei by Mackey, Zachary B, O'Brien, Theresa C, Greenbaum, Doron C, Blank, Rebecca B, McKerrow, James H

“…Identification and analysis of Clan CA (papain) cysteine proteases in primitive protozoa and metazoa have suggested that this enzyme family is more diverse and…”
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Counter-stories of my social science academic and career development from a critical "praxticioner" and "conscious-preneur": Through the lens of critical race theory and the "sociological imagination" by Mackey, Janiece Z

“…As an African American, female critical “praxticioner” and “conscious-preneur,” I have experienced racial micro-aggressions and racial battle fatigue while…”
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Utility of CD117 immunoreactivity in differentiating metastatic melanoma from clear cell sarcoma by Garcia, Joaquin J, Kramer, Miranda J, Mackey, Zachary B, O'Donnell, Richard J, Horvai, Andrew E

“…Clear cell sarcoma is a malignant soft tissue tumor with melanocytic differentiation. Molecular methods are sometimes necessary to identify the unique t(12;…”
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Counter-stories of my social science academic and career development from a critical "praxticioner" and "conscious-preneur": Through the lens of critical race theory and the "sociological imagination" by Mackey, Janiece Z

“…As an African American, female critical "praxticioner" and "conscious-preneur," I have experienced racial micro-aggressions and racial battle fatigue while…”
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