Search Results - "Mackenzie, R"

Estimated Projection of US Cancer Incidence and Death to 2040 by Rahib, Lola, Wehner, Mackenzie R, Matrisian, Lynn M, Nead, Kevin T

“…Coping with the current and future burden of cancer requires an in-depth understanding of trends in cancer incidences and deaths. Estimated projections of…”
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Underestimation of Cutaneous Squamous Cell Carcinoma Incidence, Even in Cancer Registries by Wehner, Mackenzie R

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The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D by Liu, Lucy, MacKenzie, Kevin R., Putluri, Nagireddy, Maletić-Savatić, Mirjana, Bellen, Hugo J.

“…Elevated reactive oxygen species (ROS) induce the formation of lipids in neurons that are transferred to glia, where they form lipid droplets (LDs). We show…”
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Clinical Evidence on "Watchful Waiting" in Basal Cell Carcinoma by Wehner, Mackenzie R

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Use of Procalcitonin in Patients With Various Degrees of Chronic Kidney Disease Including Renal Replacement Therapy by Grace, Eddie, Turner, R. Mackenzie

“…Procalcitonin (PCT) has been shown to be a useful surrogate marker in identifying patients with various bacterial infections. PCT has been studied as a…”
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TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia by Mackenzie, Ian RA, Prof, Rademakers, Rosa, PhD, Neumann, Manuela, Dr

“…Summary Abnormal intracellular protein aggregates comprise a key characteristic in most neurodegenerative diseases, including amyotrophic lateral sclerosis…”
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Subcortical TDP-43 pathology patterns validate cortical FTLD-TDP subtypes and demonstrate unique aspects of C9orf72 mutation cases by Mackenzie, Ian R., Neumann, Manuela

“…Frontotemporal lobar degeneration with TDP-43 immunoreactive (TDP-ir) inclusions (FTLD-TDP) is sub-classified based on the pattern of neocortical pathology,…”
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Sex differences in stress-related alcohol use by Peltier, MacKenzie R., Verplaetse, Terril L., Mineur, Yann S., Petrakis, Ismene L., Cosgrove, Kelly P., Picciotto, Marina R., McKee, Sherry A.

“…Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten years relative to a 35% increase in men. This substantive increase in…”
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Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation by Lui, Hansen, Zhang, Jiasheng, Makinson, Stefanie R., Cahill, Michelle K., Kelley, Kevin W., Huang, Hsin-Yi, Shang, Yulei, Oldham, Michael C., Martens, Lauren Herl, Gao, Fuying, Coppola, Giovanni, Sloan, Steven A., Hsieh, Christine L., Kim, Charles C., Bigio, Eileen H., Weintraub, Sandra, Mesulam, Marek-Marsel, Rademakers, Rosa, Mackenzie, Ian R., Seeley, William W., Karydas, Anna, Miller, Bruce L., Borroni, Barbara, Ghidoni, Roberta, Farese, Robert V., Paz, Jeanne T., Barres, Ben A., Huang, Eric J.

“…Microglia maintain homeostasis in the brain, but whether aberrant microglial activation can cause neurodegeneration remains controversial. Here, we use…”
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A new subtype of frontotemporal lobar degeneration with FUS pathology by Neumann, Manuela, Rademakers, Rosa, Roeber, Sigrun, Baker, Matt, Kretzschmar, Hans A., Mackenzie, Ian R. A.

“…Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular basis. The neuropathology associated with most FTD is characterized by…”
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Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS by DeJesus-Hernandez, Mariely, Mackenzie, Ian R., Boeve, Bradley F., Boxer, Adam L., Baker, Matt, Rutherford, Nicola J., Nicholson, Alexandra M., Finch, NiCole A., Flynn, Heather, Adamson, Jennifer, Kouri, Naomi, Wojtas, Aleksandra, Sengdy, Pheth, Hsiung, Ging-Yuek R., Karydas, Anna, Seeley, William W., Josephs, Keith A., Coppola, Giovanni, Geschwind, Daniel H., Wszolek, Zbigniew K., Feldman, Howard, Knopman, David S., Petersen, Ronald C., Miller, Bruce L., Dickson, Dennis W., Boylan, Kevin B., Graff-Radford, Neill R., Rademakers, Rosa

“…Several families have been reported with autosomal-dominant frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), genetically linked to…”
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Epigenetic considerations in aquaculture by Gavery, Mackenzie R, Roberts, Steven B

“…Epigenetics has attracted considerable attention with respect to its potential value in many areas of agricultural production, particularly under conditions…”
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Goals of Care: Understanding the Outcomes that Matter Most by Cook, Mackenzie R

“…Advanced care planning is a critically important part of the care of seriously and critically ill patients. A responsibility of all physicians as part of…”
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Sustenance and sustainability: maximizing the impact of school gardens on health outcomes by Davis, Jaimie N, Spaniol, Mackenzie R, Somerset, Shawn

“…School garden programmes have become popular action-oriented learning environments in many countries, often driven by converging priorities of environmental…”
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The neuropathology associated with repeat expansions in the C9ORF72 gene by Mackenzie, Ian R. A., Frick, Petra, Neumann, Manuela

“…An abnormal expansion of a GGGGCC hexanucleotide repeat in a non-coding region of the chromosome 9 open reading frame 72 gene ( C9ORF72 ) is the most common…”
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Memorable Messages from Family Members About Mental Health: Young Adult Perceptions of Relational Closeness, Message Satisfaction, and Clinical Help-Seeking Attitudes by Greenwell, Mackenzie R.

“…This study investigates memorable messages about mental health that young adults (YAs) recall receiving from family members. A memorable messages conceptual…”
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Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers by Mackenzie, Ian R. A., Frick, Petra, Grässer, Friedrich A., Gendron, Tania F., Petrucelli, Leonard, Cashman, Neil R., Edbauer, Dieter, Kremmer, Elisabeth, Prudlo, Johannes, Troost, Dirk, Neumann, Manuela

“…Hexanucleotide repeat expansion in C9ORF72 is the most common genetic cause of frontotemporal dementia and motor neuron disease. One consequence of the…”
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Review: Neuropathology of non‐tau frontotemporal lobar degeneration by Neumann, M., Mackenzie, I. R. A.

“…Frontotemporal dementia (FTD) is a heterogeneous clinical syndrome associated with frontotemporal lobar degeneration (FTLD) as a relatively consistent…”
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Perceived risk and benefits of e-cigarette use among college students by Copeland, Amy L., Peltier, MacKenzie R., Waldo, Krystal

“…Recent data demonstrates that the use of e-cigarettes is growing, especially among college students and young adults. This trend is increasingly problematic,…”
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The central role of myostatin in skeletal muscle and whole body homeostasis by Elliott, B., Renshaw, D., Getting, S., Mackenzie, R.

“…Myostatin is a powerful negative regulator of skeletal muscle mass in mammalian species. It plays a key role in skeletal muscle homeostasis and has now been…”
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