Search Results - "Mackay, C."

The neural basis of flashback formation: the impact of viewing trauma by Bourne, C, Mackay, C E, Holmes, E A

“…Psychological traumatic events, such as war or road traffic accidents, are widespread. A small but significant proportion of survivors develop post-traumatic…”
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The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis by Huang, Wen, Mackay, Trudy F C

“…Classical quantitative genetic analyses estimate additive and non-additive genetic and environmental components of variance from phenotypes of related…”
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On‐tissue chemical derivatization in mass spectrometry imaging by Harkin, Carla, Smith, Karl W., Cruickshank, Faye L., Logan Mackay, C., Flinders, Bryn, Heeren, Ron M. A., Moore, Tara, Brockbank, Simon, Cobice, Diego F.

“…Mass spectrometry imaging (MSI) combines molecular and spatial information in a valuable tool for a wide range of applications. Matrix‐assisted laser…”
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A systematic review of estimates of the minimal clinically important difference and patient acceptable symptom state of the Western Ontario and McMaster Universities Osteoarthritis Index in patients who underwent total hip and total knee replacement by MacKay, C., Clements, N., Wong, R., Davis, A.M.

“…To systematically review the minimal clinically important difference (MCID) and patient acceptable symptom state (PASS) estimates in pain and function measured…”
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The genetics of quantitative traits: challenges and prospects by Mackay, Trudy F. C, Stone, Eric A, Ayroles, Julien F

“…Key Points Most phenotypic variation in natural populations is attributable to multiple interacting loci, with allelic effects that are sensitive to the exact…”
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Spatial distribution of isobaric androgens in target tissues using chemical derivatization and MALDI-2 on a trapped ion mobility quadrupole time-of-flight instrument by Mackay, C. L. Logan, Soltwisch, Jens, Heijs, Bram, Smith, Karl W, Cruickshank, Faye L, Nyhuis, Annika, Dreisewerd, Klaus, Cobice, Diego

“…Prostate cancer is initially treated via androgen deprivation therapy (ADT), a highly successful treatment in the initial pursuit of tumour regression, but…”
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Utilising Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) to track the oxidation of lignin by an alkaliphilic laccase by Towle, Zak, Cruickshank, Faye, Mackay, C Logan, Clarke, David J, Horsfall, Louise E

“…Lignin is a complex heteroaromatic polymer which is one of the most abundant and diverse biopolymers on the planet. It comprises approximately one third of all…”
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Identification and proteomic profiling of exosomes in human cerebrospinal fluid by Street, Jonathan M, Barran, Perdita E, Mackay, C Logan, Weidt, Stefan, Balmforth, Craig, Walsh, Tim S, Chalmers, Rod T A, Webb, David J, Dear, James W

“…Exosomes are released from multiple cell types, contain protein and RNA species, and have been exploited as a novel reservoir for disease biomarker discovery…”
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Fruit softening: evidence for rhamnogalacturonan lyase action in vivo in ripe fruit cell walls by Al-Hinai, Thurayya Z S, Mackay, C Logan, Fry, Stephen C

“…The softening of ripening fruit involves partial depolymerization of cell-wall pectin by three types of reaction: enzymic hydrolysis, enzymic elimination…”
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Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis by Filippini, N, Douaud, G, Mackay, C E, Knight, S, Talbot, K, Turner, M R

“…While the hallmark of amyotrophic lateral sclerosis (ALS) is corticospinal tract in combination with lower motor neuron degeneration, the clinical involvement…”
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Mass Spectrometry Imaging for Dissecting Steroid Intracrinology within Target Tissues by Cobice, Diego F, Mackay, C. Logan, Goodwin, Richard J. A, McBride, Andrew, Langridge-Smith, Patrick R, Webster, Scott P, Walker, Brian R, Andrew, Ruth

“…Steroid concentrations within tissues are modulated by intracellular enzymes. Such “steroid intracrinology” influences hormone-dependent cancers and obesity…”
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Gregor Mendel's legacy in quantitative genetics by Mackay, Trudy F C, Anholt, Robert R H

“…Gregor Mendel's discovery of the laws of segregation and independent assortment and his inference of the existence of non-mendelian interactions between loci…”
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Quantitative Genetics of Food Intake in Drosophila melanogaster by Garlapow, Megan E, Huang, Wen, Yarboro, Michael T, Peterson, Kara R, Mackay, Trudy F C

“…Food intake is an essential animal activity, regulated by neural circuits that motivate food localization, evaluate nutritional content and acceptance or…”
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High resolution fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) for the characterisation of enzymatic processing of commercial lignin by Echavarri-Bravo, Virginia, Tinzl, Matthias, Kew, Will, Cruickshank, Faye, Logan Mackay, C., Clarke, David J., Horsfall, Louise E.

“…•FT-ICR MS allows changes in the chemical diversity of lignin to be monitored.•A laccase from T.versicolor targeted sulfur-containing polymeric lignin…”
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The APOE [varepsilon]4 allele modulates brain white matter integrity in healthy adults by Heise, V, Filippini, N, Ebmeier, K P, Mackay, C E

“…The Apolipoprotein E (APOE) 4 allele is the best-established genetic risk factor for sporadic Alzheimer's disease, and is also associated with structural gray…”
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The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster by Hunter, Chad M, Huang, Wen, Mackay, Trudy F C, Singh, Nadia D

“…Meiotic recombination ensures proper chromosome segregation in many sexually reproducing organisms. Despite this crucial function, rates of recombination are…”
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Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster by Ober, Ulrike, Ayroles, Julien F, Stone, Eric A, Richards, Stephen, Zhu, Dianhui, Gibbs, Richard A, Stricker, Christian, Gianola, Daniel, Schlather, Martin, Mackay, Trudy F C, Simianer, Henner

“…Predicting organismal phenotypes from genotype data is important for plant and animal breeding, medicine, and evolutionary biology. Genomic-based phenotype…”
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Implementation of virtual pulmonary rehabilitation during the COVID-19 pandemic: Experiences and perceptions of patients and healthcare providers by Verweel, L., Packham, T., Goldstein, R., Brooks, D., MacKay, C.

“…Pulmonary rehabilitation (PR) plays an important role in the management of symptomatic patients with chronic respiratory diseases (CRD). While studies have…”
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Development and Application of Desorption Electrospray Ionization Mass Spectrometry for Historical Dye Analysis by Sandström, Edith, Vettorazzo, Chiara, Mackay, C. Logan, Troalen, Lore G., Hulme, Alison N.

“…A desorption electrospray ionization (DESI) source was built and attached to a Bruker 7T SolariX FT-ICR-MS for the in situ analysis of 14 early synthetic…”
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Conservation of the structural and functional architecture of encapsulated ferritins in bacteria and archaea by He, Didi, Piergentili, Cecilia, Ross, Jennifer, Tarrant, Emma, Tuck, Laura R, Mackay, C Logan, McIver, Zak, Waldron, Kevin J, Clarke, David J, Marles-Wright, Jon

“…Ferritins are a large family of intracellular proteins that protect the cell from oxidative stress by catalytically converting Fe(II) into less toxic Fe(III)…”
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