Search Results - "Mack, Volker"

CKAMP44: A Brain-Specific Protein Attenuating Short-Term Synaptic Plasticity in the Dentate Gyrus by von Engelhardt, Jakob, Mack, Volker, Sprengel, Rolf, Kavenstock, Netta, Li, Ka Wan, Stern-Bach, Yael, Smit, August B, Seeburg, Peter H, Monyer, Hannah

“…CKAMP44, identified here by a proteomic approach, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines…”
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Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study by Carty, Nikisha, Berson, Nadège, Tillack, Karsten, Thiede, Christina, Scholz, Diana, Kottig, Karsten, Sedaghat, Yalda, Gabrysiak, Christina, Yohrling, George, von der Kammer, Heinz, Ebneth, Andreas, Mack, Volker, Munoz-Sanjuan, Ignacio, Kwak, Seung

“…Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the huntingtin gene. Major…”
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State-dependent Ras signaling and AMPA receptor trafficking by Qin, Yi, Zhu, Yinghua, Baumgart, Joel P, Stornetta, Ruth L, Seidenman, Kenneth, Mack, Volker, van Aelst, Linda, Zhu, J Julius

“…Synaptic trafficking of AMPA-Rs, controlled by small GTPase Ras signaling, plays a key role in synaptic plasticity. However, how Ras signals synaptic AMPA-R…”
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GluA1 and its PDZ-interaction: A role in experience-dependent behavioral plasticity in the forced swim test by Freudenberg, Florian, Marx, Verena, Mack, Volker, Layer, Liliana E, Klugmann, Matthias, Seeburg, Peter H, Sprengel, Rolf, Celikel, Tansu

“…Abstract Glutamate receptor dependent synaptic plasticity plays an important role in the pathophysiology of depression. Hippocampal samples from clinically…”
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Glutamatergic Plasticity by Synaptic Delivery of GluR-Blong-Containing AMPA Receptors by Kolleker, Alexander, Zhu, J.Julius, Schupp, Bettina J, Qin, Yi, Mack, Volker, Borchardt, Thilo, Köhr, Georg, Malinow, Roberto, Seeburg, Peter H, Osten, Pavel

“…Activity-driven delivery of AMPA receptors is proposed to mediate glutamatergic synaptic plasticity, both during development and learning. In hippocampal CA1…”
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Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors by Shimshek, Derya R, Bus, Thorsten, Kim, Jinhyun, Mihaljevic, Andre, Mack, Volker, Seeburg, Peter H, Sprengel, Rolf, Schaefer, Andreas T

“…Genetic perturbations of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are widely used to dissect molecular mechanisms of sensory…”
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Conditional Restoration of Hippocampal Synaptic Potentiation in GluR-A-Deficient Mice by Mack, Volker, Burnashev, Nail, Katharina M. M. Kaiser, Rozov, Andrei, Jensen, Vidar, Hvalby, Øvind, Seeburg, Peter H., Sakmann, Bert, Sprengel, Rolf

“…Plasticity of mature hippocampal CA1 synapses is dependent on L-α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate…”
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SA97. Elevated GPR85 Expression in Rat Hippocampus Impairs Spatial Short-Term Memory by an Unknown Molecular Mechanism by Mack, Volker, Koros, Eliza

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1528-P: Investigate Functional Dynamics of Neuropeptides in Acute Brain Slices to Predict Anorexigenic Efficacy by Pekcec, Anton, Altas, Bekir, Bruschetta, Giuseppe, Buzzanca, Anna, Doerr, Jonas, Lam, Daniel, Lincoln, Kathleen A, Mack, Volker

“…Obesity represents the largest and rapidly escalating global health crisis in the world, predominantly attributed to a disequilibrium between caloric intake…”
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Increasing the Excitatory Drive Rescues Excitatory/Inhibitory Imbalance and Mismatch Negativity Deficit Caused by Parvalbumin Specific GluA1 Deletion by Chen-Engerer, Hsing-Jung, Jaeger, Stefan, Bondarenko, Rimma, Sprengel, Rolf, Hengerer, Bastian, Rosenbrock, Holger, Mack, Volker, Schuelert, Niklas

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M181. DEVELOPMENTAL PROGRESSION OF INTERNEURON NETWORK DEFICITS IN A 15Q13.3 MICRODELETION MOUSE MODEL – A GLIMPSE ON ADOLESCENT PRIMING FOR SCHIZOPHRENIA? by Funk, Marzieh, Jaeger, Stefan, Schülert, Niklas, Dorner-Ciossek, Cornelia, Rosenbrock, Holger, Mack, Volker

“…Abstract Background Schizophrenia is a complex neurodevelopmental disorder. Patients typically start exhibiting symptoms during adolescence, coinciding with a…”
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Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule by Tautermann, Christofer S, Binder, Florian, Büttner, Frank H, Eickmeier, Christian, Fiegen, Dennis, Gross, Ulrike, Grundl, Marc A, Heilker, Ralf, Hobson, Scott, Hoerer, Stefan, Luippold, Andreas, Mack, Volker, Montel, Florian, Peters, Stefan, Bhattacharya, Supriyo, Vaidehi, Nagarajan, Schnapp, Gisela, Thamm, Sven, Zeeb, Markus

“…Protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) is a brain specific phosphatase that regulates synaptic function and plasticity by modulation of…”
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F196. Transgenic Overexpression of the Type III Isoform of Neuregulin 1 in Mice Induces Abnormalities on Auditory Event Related EEG Biomarkers Related to Schizophrenia Accompanied by Reduction of Parvalbumin Positive Interneurons in the Prefrontal Cortex by Schuelert, Niklas, Nissen, Wiebke, Mack, Volker, Jaeger, Stefan, Arban, Roberto, Schwab, Markus, Rossner, Moritz, Dorner-Ciossek, Cornelia, Rosenbrock, Holger

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Structure of Mammalian Serine Racemase: EVIDENCE FOR CONFORMATIONAL CHANGES UPON INHIBITOR BINDING by Smith, Myron A, Mack, Volker, Ebneth, Andreas, Moraes, Isabel, Felicetti, Brunella, Wood, Michael, Schonfeld, Dorian, Mather, Owen, Cesura, Andrea, Barker, John

“…Serine racemase is responsible for the synthesis of D-serine, an endogenous co-agonist for N-methyl-D-aspartate receptor-type glutamate receptors (NMDARs)…”
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D06 Quantitative assays to monitor huntingtin changes in pre-clinical and clinical hd samples by Kuhlbrodt, Kirsten, Baldo, Barbara, Reindl, Wolfgang, Carty, Nikisha, Tillack, Karsten, Berson, Nadege, Mack, Volker, Bazenet, Chantal, Herrmann, Frank, vanderKam, Elizabeth, Bard, Jonathan, Munoz-Sanjuan, Ignacio, Macdonald, Douglas

“…BackgroundHuntington’s disease (HD) is a progressive neurodegenerative disease caused by a polyglutamine repeat expansion in the huntingtin (HTT) protein with…”
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Noelin1 Affects Lateral Mobility of Synaptic AMPA Receptors by Pandya, Nikhil J., Seeger, Christian, Babai, Norbert, Gonzalez-Lozano, Miguel A., Mack, Volker, Lodder, Johannes C., Gouwenberg, Yvonne, Mansvelder, Huibert D., Danielson, U. Helena, Li, Ka Wan, Heine, Martin, Spijker, Sabine, Frischknecht, Renato, Smit, August B.

“…Lateral diffusion on the neuronal plasma membrane of the AMPA-type glutamate receptor (AMPAR) serves an important role in synaptic plasticity. We investigated…”
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Neural adaption in midbrain GABAergic cells contributes to high-fat diet–induced obesity by Wang, Xiaomeng, Wu, Xiaotong, Wu, Hao, Xiao, Hanyang, Hao, Sijia, Wang, Bingwei, Li, Chen, Bleymehl, Katherin, Kauschke, Stefan G., Mack, Volker, Ferger, Boris, Klein, Holger, Zheng, Ruimao, Duan, Shumin, Wang, Hao

“…Overeating disorders largely contribute to worldwide incidences of obesity. Available treatments are limited. Here, we discovered that long-term chemogenetic…”
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Characterization of HTT Inclusion Size, Location, and Timing in the zQ175 Mouse Model of Huntington´s Disease: An In Vivo High-Content Imaging Study by Carty, Nikisha, Berson, Nadège, Tillack, Karsten, Thiede, Christina, Scholz, Diana, Kottig, Karsten, Sedaghat, Yalda, Gabrysiak, Christina, Yohrling, George, von der Kammer, Heinz, Ebneth, Andreas, Mack, Volker, Munoz-Sanjuan, Ignacio, Kwak, Seung

“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the huntingtin gene. Major…”
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Forebrain-Specific Glutamate Receptor B Deletion Impairs Spatial Memory But Not Hippocampal Field Long-Term Potentiation by Shimshek, Derya R, Jensen, Vidar, Celikel, Tansu, Geng, Yu, Schupp, Bettina, Bus, Thorsten, Mack, Volker, Marx, Verena, Hvalby, Oivind, Seeburg, Peter H, Sprengel, Rolf

“…We demonstrate the fundamental importance of glutamate receptor B (GluR-B) containing AMPA receptors in hippocampal function by analyzing mice with conditional…”
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The Structure of Mammalian Serine Racemase by Smith, Myron A., Mack, Volker, Ebneth, Andreas, Moraes, Isabel, Felicetti, Brunella, Wood, Michael, Schonfeld, Dorian, Mather, Owen, Cesura, Andrea, Barker, John

“…Serine racemase is responsible for the synthesis of d-serine, an endogenous co-agonist for N-methyl-d-aspartate receptor-type glutamate receptors (NMDARs)…”
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