Search Results - "Mack, Lydia E"
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The minichromosome maintenance complex drives esophageal basal zone hyperplasia
Published in JCI insight (08-09-2023)“…Eosinophilic esophagitis (EoE) is a chronic gastrointestinal disorder characterized by food antigen-driven eosinophilic inflammation and hyperproliferation of…”
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Environmental allergens trigger type 2 inflammation through ripoptosome activation
Published in Nature immunology (01-10-2021)“…Environmental allergens, including fungi, insects and mites, trigger type 2 immunity; however, the innate sensing mechanisms and initial signaling events…”
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Molecular analysis of duodenal eosinophilia
Published in Journal of allergy and clinical immunology (01-04-2023)“…Eosinophilic duodenitis (EoD), characterized by nonspecific gastrointestinal symptoms and increased numbers of duodenal eosinophils, may be in the eosinophilic…”
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4
An Update on the Acinetobacter baumannii Regulatory Circuitry
Published in Trends in microbiology (Regular ed.) (01-07-2018)“…Acinetobacter baumannii adapts to different environmental conditions by expressing complex regulatory circuitry. Recent studies revealed that this circuitry…”
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Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling
Published in Gut (01-05-2023)“…The contribution of vitamin D (VD) deficiency to the pathogenesis of allergic diseases remains elusive. We aimed to define the impact of VD on oesophageal…”
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Uncovering the secretes of allergic inflammation
Published in The Journal of clinical investigation (01-07-2020)“…Allergic asthma is a chronic inflammatory lung disease associated with increased cytokine secretion. Aspects of airway inflammation are also linked to a common…”
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Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell–Fibroblast Crosstalk
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2022)“…Eosinophilic esophagitis (EoE) can progress to fibrostenosis by unclear mechanisms. Herein, we investigated gene dysregulation in fibrostenotic EoE, its…”
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Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)“…Colonic eosinophilia, an enigmatic finding often referred to as eosinophilic colitis (EoC), is a poorly understood condition. Whether EoC is a distinct disease…”
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