Search Results - "Mack, D H"

How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis by Goodnow, Christopher C, Glynne, Richard, Akkaraju, Srinivas, Healy, James I, Rayner, Jane, Mack, David H

“…Therapy for transplant rejection, autoimmune disease and allergy must target mature lymphocytes that have escaped censoring during their development. FK506 and…”
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Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells by Turner, Jr, C A, Mack, D H, Davis, M M

“…We describe a novel gene, Blimp-1 (for B lymphocyte-induced maturation protein), transcripts of which are rapidly induced during the differentiation of B…”
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Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53 by Mack, David H, Vartikar, Jai, Pipas, James M, Laimins, Laimonis A

“…The p53 protein is apparently central to the development of human cancers because both alleles are often found to be mutated in different tumour types. In…”
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A Keratinocyte-Specific Transcription Factor, KRF-1, Interacts with AP-1 to Activate Expression of Human Papillomavirus Type 18 in Squamous Epithelial Cells by Mack, David H., Laimins, Laimonis A.

“…Human papillomavirus type 18 (HPV-18) infects genital squamous epithelium and is an etiological agent of cervical cancer. Cell-type-specific expression of…”
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DNA Amplification for Direct Detection of HIV-1 in DNA of Peripheral Blood Mononuclear Cells by Ou, Chin-Yih, Kwok, Shirley, Mitchell, Sheila W., Mack, David H., Sninsky, John J., Krebs, John W., Feorino, Paul, Warfield, Donna, Schochetman, Gerald

“…By means of a selective DNA amplification technique called polymerase chain reaction, proviral sequences of the human immunodeficiency virus (HIV-1) were…”
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Identification of human immunodeficiency virus sequences by using in vitro enzymatic amplification and oligomer cleavage detection by KWOK, S, MACK, D. H, MULLIS, K. B, POIESZ, B, EHRLICH, G, BLAIR, D, FRIEDMAN-KIEN, A, SNINSKY, J. J

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Analysis of p53-regulated gene expression patterns using oligonucleotide arrays by Zhao, R, Gish, K, Murphy, M, Yin, Y, Notterman, D, Hoffman, W H, Tom, E, Mack, D H, Levine, A J

“…Oligonucleotide microarrays were employed to quantitate mRNA levels from a large number of genes regulated by the p53 transcription factor. Responses to DNA…”
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Design considerations for array CGH to oligonucleotide arrays by Baldocchi, R. A., Glynne, R. J., Chin, K., Kowbel, D., Collins, C., Mack, D. H., Gray, J. W.

“…Background Representational oligonucleotide microarray analysis has been developed for detection of single nucleotide polymorphisms and/or for genome copy…”
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B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays by Glynne, R, Ghandour, G, Rayner, J, Mack, D H, Goodnow, C C

“…Self-tolerance is achieved by deleting or regulating self-reactive lymphocytes at a series of cellular checkpoints placed at many points along the…”
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A Sensitive Method for the Identification of Uncharacterized Viruses Related to Known Virus Groups: Hepadnavirus Model System by Mack, David H., Sninsky, John J.

“…Amino acid sequence similarity of the reverse transcriptases encoded by retroviruses and hepadnaviruses was first reported by Toh, H., Hayashida, H. & Miyata,…”
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Attributes of gamma delta intraepithelial lymphocytes as suggested by their transcriptional profile by Fahrer, A M, Konigshofer, Y, Kerr, E M, Ghandour, G, Mack, D H, Davis, M M, Chien, Y

“…gamma delta T lymphocytes in the intestinal intraepithelial layer ( gamma delta IELs) are thought to contribute to immune competence, but their actual function…”
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The transcriptional program following p53 activation by Zhao, R, Gish, K, Murphy, M, Yin, Y, Notterman, D, Hoffman, W H, Tom, E, Mack, D H, Levine, A J

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Detection of hepatitis B virus sequences in serum by using in vitro enzymatic amplification by Larzul, D, Guigue, F, Sninsky, J J, Mack, D H, Bréchot, C, Guesdon, J L

“…In vitro enzymatic amplification was applied to detect hepatitis B virus (HBV) DNA sequences in serum. This technique, known as the polymerase chain reaction…”
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Increased apoptosis induction by 121F mutant p53 by Saller, Elisabeth, Tom, Edward, Brunori, Michele, Otter, Michèle, Estreicher, Anne, Mack, David H., Iggo, Richard

“…p53 mutants in tumours have a reduced affinity for DNA and a reduced ability to induce apoptosis. We describe a mutant with the opposite phenotype, an…”
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Hepatitis B virus particles contain a polypeptide encoded by the largest open reading frame: a putative reverse transcriptase by MACK, D. H, BLOCH, W, NRAPENDRA NATH, SNINSKY, J. J

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Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription by LECHNER, M. S, MACK, D. H, FINICLE, A. B, CROOK, T, VOUSDEN, K. H, LAIMINS, L. A

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Serological characterization and gene localization of an Escherichia coli-expressed 37-kilodalton Treponema pallidum antigen by RODGERS, G. C, LAIRD, W. J, COATES, S. R, MACK, D. H, HUSTON, M, SNINSKY, J. J

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Tests of small airway function in black smokers and nonsmokers by Stinson, J M, McPherson, G L, Mack, D H, McCuller, J Y, Gamshadzi, A, Semenya, K A

“…Tests of small airway function (closing volume, forced expiratory flow in the middle half of the vital capacity, specific airway conductance, and peak…”
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B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays

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Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse by HENSHALL, Susan M, AFAR, Daniel E. H, STRICKER, Phillip D, SCHER, Howard I, GRYGIEL, John J, AGUS, David B, MACK, David H, SUTHERLAND, Robert L, HILLER, Jordan, HORVATH, Lisa G, QUINN, David I, RASIAH, Krishan K, GISH, Kurt, WILLHITE, Dorian, KENCH, James G, GARDINER-GARDEN, Margaret

“…Current models of prostate cancer classification are poor at distinguishing between tumors that have similar histopathological features but vary in clinical…”
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