Search Results - "Mack, Brigitte"
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CD44s and CD44v6 expression in head and neck epithelia
Published in PloS one (09-10-2008)“…CD44 splice variants are long-known as being associated with cell transformation. Recently, the standard form of CD44 (CD44s) was shown to be part of the…”
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CXC Chemokine Receptor 4 is Essential for Maintenance of Renal cell Carcinoma‐Initiating Cells and Predicts Metastasis
Published in Stem cells (Dayton, Ohio) (01-08-2013)“…In many solid tumors, cancer stem cells (CSC) represent a population with tumor‐initiating, self‐renewal, and differentiation potential, which can be…”
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B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice
Published in Blood (17-02-2011)“…The ubiquitin-editing enzyme A20/TNFAIP3 is essential for controlling signals inducing the activation of nuclear factor-κB transcription factors. Polymorphisms…”
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EpCAM Is Involved in Maintenance of the Murine Embryonic Stem Cell Phenotype
Published in Stem cells (Dayton, Ohio) (01-08-2009)“…Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein that is expressed on subsets of normal epithelia, numerous stem‐ and progenitor‐type…”
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Heterogeneous Nuclear Ribonucleoprotein H Blocks MST2-Mediated Apoptosis in Cancer Cells by Regulating a-raf Transcription
Published in Cancer research (Chicago, Ill.) (15-02-2010)“…A-Raf belongs to the family of oncogenic Raf kinases that are involved in mitogenic signaling by activating the mitogen-activated protein (MAP)/extracellular…”
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The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation
Published in Oncogene (29-07-2004)“…Epithelial cell adhesion molecule (EpCAM) is a membrane glycoprotein expressed on adenomatous and simple epithelia, where it is involved in homophilic adhesion…”
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Initial activation of EpCAM cleavage via cell-to-cell contact
Published in BMC cancer (19-11-2009)“…Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein, which is frequently over-expressed in simple epithelia, progenitors, embryonic and…”
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CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling
Published in Blood (08-12-2011)“…B cell–specific gene ablation of Notch2 results in the loss of the marginal zone (MZ) B-cell lineage. To analyze the effects of constitutive Notch2 signaling…”
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9
Keratin 8 expression in head and neck epithelia
Published in BMC cancer (22-09-2008)“…The intermediate filament forming protein keratin 8 (K8) is a tumour-associated antigen, which was shown to be over-expressed in a variety of malignancies…”
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10
Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM
Published in PloS one (29-08-2013)“…Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein, which is highly and frequently expressed in carcinomas and (cancer-)stem cells, and…”
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Rapid and non-enzymatic in vitro retrieval of tumour cells from surgical specimens
Published in PloS one (31-01-2013)“…The study of tumourigenesis commonly involves the use of established cell lines or single cell suspensions of primary tumours. Standard methods for the…”
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12
Analysis of Plasmacytoid and Myeloid Dendritic Cells in Nasal Epithelium
Published in Clinical and Vaccine Immunology (01-11-2006)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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13
Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis
Published in BMC cancer (11-03-2010)“…Squamous cell carcinoma of the head and neck (SCCHN) are highly invasive tumours with frequent local and distant recurrence. Metastasis formation requires…”
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14
CD133 is a predictor of poor survival in head and neck squamous cell carcinomas
Published in Cancer biomarkers : section A of Disease markers (01-01-2012)“…The pentaspan protein CD133 (Prominin-1) is a predictive marker and part of the signature of tumour-initiating cells (TICs) for various cancer entities. The…”
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15
Increased densities of monocarboxylate transport protein MCT1 after chronic administration of nicotine in rat brain
Published in Neuroscience research (01-08-2009)“…Chronic administration of nicotine is followed by a general stimulation of brain metabolism that results in a distinct increase of glucose transport protein…”
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Soluble CD44v6 is Not a Sensitive Tumor Marker in Patients with Head and Neck Squamous Cell Cancer
Published in Anticancer research (01-07-2005)“…Background: In some epithelial tumors, isoforms of CD44 are overexpressed and soluble isoforms detectable in serum samples are elevated. In squamous cell…”
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Nuclear signalling by tumour-associated antigen EpCAM
Published in Nature cell biology (01-02-2009)“…The intracellular fragment of the adhesion molecule EpCAM, which is generated by the proteases TACE and presenilin-2, increases cell proliferation and acts in…”
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Biodistribution and Radioimmunotherapy of SCCHN in Xenotransplantated SCID Mice with a 131I-labelled Anti-EpCAM Monoclonal Antibody
Published in Anticancer research (01-01-2007)“…Background: The mortality from squamous cell carcinoma of the head and neck (SCCHN) remains high and almost unchanged throughout the last decades. Therefore,…”
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Antitumour Effects of a Bispecific Trivalent Antibody in Multicellular Tumour Spheroids
Published in Anticancer research (01-03-2004)“…Background: New adjuvant immunological therapies that selectively redirect effector cells towards tumour cells are currently under development. These…”
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Cleavage and Cell Adhesion Properties of Human Epithelial Cell Adhesion Molecule (HEPCAM)
Published in The Journal of biological chemistry (02-10-2015)“…Human epithelial cell adhesion molecule (HEPCAM) is a tumor-associated antigen frequently expressed in carcinomas, which promotes proliferation after regulated…”
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