Search Results - "Maciel, Rui M.B."
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Liothyronine and Desiccated Thyroid Extract in the Treatment of Hypothyroidism
Published in Thyroid (New York, N.Y.) (01-10-2020)“…The basis for the treatment of hypothyroidism with levothyroxine (LT4) is that humans activate T4 to triiodothyronine (T3). Thus, while normalizing serum…”
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New cases of isolated congenital central hypothyroidism due to homozygous thyrotropin beta gene mutations: a pitfall to neonatal screening
Published in Thyroid (New York, N.Y.) (01-06-2010)“…Congenital central hypothyroidism (CCH) is a rare condition that is often diagnosed in late childhood in countries where neonatal screening programs rely…”
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3
Serum Thyrotropin and Triiodothyronine Levels in Levothyroxine-treated Patients
Published in The journal of clinical endocrinology and metabolism (01-06-2023)“…Abstract Context Small adjustments in levothyroxine (LT4) dose do not appear to provide clinical benefit despite changes in thyrotropin (TSH) levels within the…”
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4
Mutations in Potassium Channel Kir2.6 Cause Susceptibility to Thyrotoxic Hypokalemic Periodic Paralysis
Published in Cell (08-01-2010)“…Thyrotoxic hypokalemic periodic paralysis (TPP) is characterized by acute attacks of weakness, hypokalemia, and thyrotoxicosis of various etiologies. These…”
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Relationship between GH response and glycemic fluctuations in the glucagon stimulation test
Published in Growth hormone & IGF research (01-02-2009)“…Abstract Objective: Verifying the association between glycemic fluctuation and GH response in the glucagon stimulation test. Basal evaluation of growth hormone…”
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Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells
Published in The Journal of clinical investigation (01-06-2010)“…Hypothyroidism in humans is characterized by severe neurological consequences that are often irreversible, highlighting the critical role of thyroid hormone…”
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Dipeptidyl peptidase IV inhibition upregulates GLUT4 translocation and expression in heart and skeletal muscle of spontaneously hypertensive rats
Published in European journal of pharmacology (05-01-2013)“…The purpose of the current study was to test the hypothesis that the dipeptidyl peptidase IV (DPPIV) inhibitor sitagliptin, which exerts anti-hyperglycemic and…”
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One month is sufficient for urinary iodine to return to its baseline value after the use of water-soluble iodinated contrast agents in post-thyroidectomy patients requiring radioiodine therapy
Published in Thyroid (New York, N.Y.) (01-09-2012)“…There is a concern regarding the use of iodinated contrast agents (ICA) for chest and neck computed tomography (CT) to localize metastatases in patients with…”
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Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer’s Disease
Published in Metabolic brain disease (01-12-2022)“…Alzheimer disease’s (AD) is a neurodegenerative disorder characterized by cognitive and behavioral impairment. The central nervous system is an important…”
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Assessment of Depression, Anxiety, Quality of Life, and Coping in Long-Standing Multiple Endocrine Neoplasia Type 2 Patients
Published in Thyroid (New York, N.Y.) (01-05-2017)“…Data on psychological harm in multiple endocrine neoplasia type 2 (MEN2) are scarce. The aim of this study was to assess anxiety, depression, quality of life,…”
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11
Use of Statins Among Patients Taking Levothyroxine: an Observational Drug Utilization Study Across Sites
Published in Journal of the Endocrine Society (01-07-2021)“…Abstract Context Treatment with levothyroxine (LT4) that normalize serum thyrotropin (TSH) is expected to restore lipid metabolism. Objective To assess statin…”
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Fine needle aspiration and medullary thyroid carcinoma: the risk of inadequate preoperative evaluation and initial surgery when relying upon FNAB cytology alone
Published in Endocrine practice (01-11-2013)“…To evaluate the diagnostic accuracy of fine-needle aspiration biopsy (FNAB) to preoperatively diagnose medullary thyroid cancer (MTC) among multiple…”
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Novel etiopathophysiological aspects of thyrotoxic periodic paralysis
Published in Nature reviews. Endocrinology (01-11-2011)“…Thyrotoxic periodic paralysis (TPP) is an endocrine channelopathy that is often underdiagnosed. TPP results from the combination of genetic susceptibility,…”
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Parity is not related to autoimmune thyroid disease in a population-based study of Japanese-Brazilians
Published in Thyroid (New York, N.Y.) (01-10-2010)“…It has been suggested that the female preponderance for autoimmune thyroid disease might be associated with hormonal differences, abortion, and fetal…”
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The RET p.G533C mutation confers predisposition to multiple endocrine neoplasia type 2A in a Brazilian kindred and is able to induce a malignant phenotype in vitro and in vivo
Published in Thyroid (New York, N.Y.) (01-09-2011)“…We have previously described a p.G533C substitution in the rearranged during transfection (RET) oncogene in a large family with medullary thyroid carcinoma…”
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Bethesda Classification and Cytohistological Correlation of Thyroid Nodules in a Brazilian Thyroid Disease Center
Published in European thyroid journal (01-06-2018)“…Background: The Bethesda System has been used to classify thyroid cytology in 6 categories besides presenting malignancy rates and respective approaches…”
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Impaired metabolic effects of a thyroid hormone receptor beta-selective agonist in a mouse model of diet-induced obesity
Published in Thyroid (New York, N.Y.) (01-05-2010)“…The use of selective agonists of the thyroid hormone receptor isoform beta (TRbeta) has been linked to metabolic improvement in animal models of diet-induced…”
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Clinical and molecular analysis of thyroid hypoplasia: a population-based approach in southern Brazil
Published in Thyroid (New York, N.Y.) (01-01-2009)“…Congenital hypothyroidism (CH) is mainly due to developmental abnormalities leading to thyroid dysgenesis (TD). TD encompasses very distinct morphologic…”
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Diagnosis of Suspicious Thyroid Nodules Using Four Protein Biomarkers
Published in Clinical cancer research (01-06-2006)“…Purpose: Fine-needle aspiration (FNA) cytology, a standard method for thyroid nodule diagnosis, cannot distinguish between benign follicular thyroid adenoma…”
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Analysis of somatic mutations in BRAF, CDKN2A/p16 and PI3KCA in patients with medullary thyroid carcinoma
Published in Molecular medicine reports (01-02-2016)“…Medullary thyroid carcinoma (MTC), a neuroendocrine tumor originating from thyroid parafollicular cells, has been demonstrated to be associated with mutations…”
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