Search Results - "Maciejewski, Patricia M."
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Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis
Published in Nature chemical biology (01-01-2011)“…Binding of the small-molecule inhibitor CGI1746 to Bruton's tyrosine kinase (Btk), a therapeutic target for rheumatoid arthritis, induces an inactive Btk…”
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Imidazo[1,2-a]pyrazine diaryl ureas: Inhibitors of the receptor tyrosine kinase EphB4
Published in Bioorganic & medicinal chemistry letters (15-12-2009)“…The identification of imidazo[1,2-a]pyrazine diarylureas as potent inhibitors of the receptor tyrosine kinaseEphB4 is reported. Inhibition of receptor tyrosine…”
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Mutation of serine 90 to glutamic acid mimics phosphorylation of bovine prolactin
Published in The Journal of biological chemistry (17-11-1995)“…Phosphorylated prolactin has been identified and isolated from bovine pituitaries. The biological activity of this phosphoprotein is severely reduced in…”
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